메뉴 건너뛰기




Volumn 137, Issue 7, 2002, Pages 1031-1038

Effects of non-steroidal anti-inflammatory drugs on cyclo-oxygenase and lipoxygenase activity in whole blood from aspirin-sensitive asthmatics vs healthy donors

Author keywords

Aspirin; Asthma; COX 1; COX 2; Cyclo oxygenase; Leukotrienes; Lipoxygenase; NSAID; Prostaglandins; Whole blood

Indexed keywords

5,5 DIMETHYL 3 (2 ISOPRPPOXY) 4 (METHANESULFONYLPHENYL) 2(5H) FURANONE; ACETYLSALICYLIC ACID; CALCIMYCIN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; INDOMETACIN; LEUKOTRIENE; LIPOPOLYSACCHARIDE; LIPOXYGENASE; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; SALICYLATE SODIUM; THROMBOXANE B2; UNCLASSIFIED DRUG; 3 2( PROPYLOXY) (4 METHYLSULFONYLPHENYL) (5,5 DIMETHYL)FURANONE; 3-2(-PROPYLOXY)-(4-METHYLSULFONYLPHENYL)-(5,5-DIMETHYL)FURANONE; BENZENE DERIVATIVE; FURAN DERIVATIVE; IONOPHORE; ISOENZYME; MEMBRANE PROTEIN; NIMESULIDE; PROSTAGLANDIN SYNTHASE INHIBITOR; PTGS1 PROTEIN, HUMAN; PTGS2 PROTEIN, HUMAN; SULFONAMIDE;

EID: 0036897789     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704927     Document Type: Article
Times cited : (48)

References (31)
  • 1
    • 0033729001 scopus 로고    scopus 로고
    • Aspirin and asthma
    • Babu, K.S. & Salvi, S.S. (2000). Aspirin and asthma. Chest, 118, 1470-1476.
    • (2000) Chest , vol.118 , pp. 1470-1476
    • Babu, K.S.1    Salvi, S.S.2
  • 2
    • 0031730079 scopus 로고    scopus 로고
    • Expression of cyclo-oxygenase-2 in human airway smooth muscle is associated with profound reductions in cell growth
    • Belvisi, M.G., Saunders, M., Yacoub, M. & Mitchell, J.A. (1998). Expression of cyclo-oxygenase-2 in human airway smooth muscle is associated with profound reductions in cell growth. Br. J. Pharmacol., 125, 1102-1108.
    • (1998) Br. J. Pharmacol. , vol.125 , pp. 1102-1108
    • Belvisi, M.G.1    Saunders, M.2    Yacoub, M.3    Mitchell, J.A.4
  • 3
    • 0031000946 scopus 로고    scopus 로고
    • Induction of cyclo-oxygenase-2 by cytokines in human cultured airway smooth muscle cells: Novel inflammatory role of this cell type
    • Belvisi, M.G., Saunders, M.A., Haddad EL, B., Hirst, S.J., Yacoub, M.H., Barnes, P.J. & Mitchell, J.A. (1997). Induction of cyclo-oxygenase-2 by cytokines in human cultured airway smooth muscle cells: Novel inflammatory role of this cell type. Br. J. Pharmacol., 120, 910-916.
    • (1997) Br. J. Pharmacol. , vol.120 , pp. 910-916
    • Belvisi, M.G.1    Saunders, M.A.2    Haddad, E.L.3    Hirst, S.J.4    Yacoub, M.H.5    Barnes, P.J.6    Mitchell, J.A.7
  • 4
    • 0030962937 scopus 로고    scopus 로고
    • Endogenous nitric oxide inhibits leukotriene B4 release from rat alveolar macrophages
    • Brunn, G., Hey, C., Wessler, I. & Racke, K. (1997). Endogenous nitric oxide inhibits leukotriene B4 release from rat alveolar macrophages. Eur. J. Pharmacol., 326, 53-60.
    • (1997) Eur. J. Pharmacol. , vol.326 , pp. 53-60
    • Brunn, G.1    Hey, C.2    Wessler, I.3    Racke, K.4
  • 5
    • 0034886127 scopus 로고    scopus 로고
    • Nitrosylhemoglobin, an unequivocal index of nitric oxide release from nitroaspirin; in vitro and in vivo studies in the rat by ESR spectroscopy
    • Carini, M., Aldini, G., Stefani, R., Orioli, M. & Facino, R.M. (2001). Nitrosylhemoglobin, an unequivocal index of nitric oxide release from nitroaspirin; in vitro and in vivo studies in the rat by ESR spectroscopy. J. Pharm. Biomed. Anal., 26, 509-518.
    • (2001) J. Pharm. Biomed. Anal. , vol.26 , pp. 509-518
    • Carini, M.1    Aldini, G.2    Stefani, R.3    Orioli, M.4    Facino, R.M.5
  • 6
    • 0026051529 scopus 로고
    • The effect of inhalation of the leukotriene receptor antagonist, SK&F 104353, on leukotriene C4- and leukotriene E4-induced bronchoconstriction in subjects with asthma
    • Christie, P.E., Spur, B.W. & Lee, T.H. (1991). The effect of inhalation of the leukotriene receptor antagonist, SK&F 104353, on leukotriene C4- and leukotriene E4-induced bronchoconstriction in subjects with asthma. J. Allergy Clin. Immunol., 88, 193-198.
    • (1991) J. Allergy Clin. Immunol. , vol.88 , pp. 193-198
    • Christie, P.E.1    Spur, B.W.2    Lee, T.H.3
  • 7
    • 0028818271 scopus 로고
    • Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions
    • Claria, J. & Serhan, C.N. (1995). Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions. Proc. Natl. Acad. Sci. U.S.A., 92, 9475-9479.
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 9475-9479
    • Claria, J.1    Serhan, C.N.2
  • 8
    • 0034287419 scopus 로고    scopus 로고
    • Prolonged exposure to lipopolysaccharide inhibits macrophage 5-lipoxygenase metabolism via induction of nitric oxide synthesis
    • Coffey, M.J., Phare, S.M. & Peters-Golden, M. (2000). Prolonged exposure to lipopolysaccharide inhibits macrophage 5-lipoxygenase metabolism via induction of nitric oxide synthesis. J. Immunol., 165, 3592-3598.
    • (2000) J. Immunol. , vol.165 , pp. 3592-3598
    • Coffey, M.J.1    Phare, S.M.2    Peters-Golden, M.3
  • 9
    • 0023243031 scopus 로고
    • Indomethacin increases the formation of lipoxygenase products in calcium ionophore stimulated human neutrophils
    • Docherty, J.C. & Wilson, T.W. (1987). Indomethacin increases the formation of lipoxygenase products in calcium ionophore stimulated human neutrophils. Biochem. Biophys. Res. Commun., 148, 534-538.
    • (1987) Biochem. Biophys. Res. Commun. , vol.148 , pp. 534-538
    • Docherty, J.C.1    Wilson, T.W.2
  • 10
    • 85054117017 scopus 로고    scopus 로고
    • Leukotriene production in human blood is reduced by NO-aspirin but not aspirin: Comparisons between responses in healthy volunteers and aspirin-sensitive asthma
    • Gray, P.A., Warner, T.D., Vojnovic, I., Parikh, A., Scadding, G., del Sodalto, P. & Mitchell, J.A. (2000). Leukotriene production in human blood is reduced by NO-aspirin but not aspirin: Comparisons between responses in healthy volunteers and aspirin-sensitive asthma. Br. J. Pharmacol., 129 (Proceedings Suppl.): P1-P296.
    • (2000) Br. J. Pharmacol. , vol.129 , Issue.PROCEEDINGS SUPPL.
    • Gray, P.A.1    Warner, T.D.2    Vojnovic, I.3    Parikh, A.4    Scadding, G.5    Del Sodalto, P.6    Mitchell, J.A.7
  • 11
    • 2542425151 scopus 로고
    • Pharmacokinetics of aspirin and salicylate in relation to inhibition of arachidonate cyclooxygenase and antiinflammatory activity
    • Higgs, G.A., Salmon, J.A., Henderson, B. & Vane, J.R. (1987). Pharmacokinetics of aspirin and salicylate in relation to inhibition of arachidonate cyclooxygenase and antiinflammatory activity. Proc. Natl. Acad. Sci. U.S.A., 84, 1417-1420.
    • (1987) Proc. Natl. Acad. Sci. U.S.A. , vol.84 , pp. 1417-1420
    • Higgs, G.A.1    Salmon, J.A.2    Henderson, B.3    Vane, J.R.4
  • 12
    • 0026801167 scopus 로고
    • Identification of a pharmacologically distinct prostaglandin H synthase in cultured epithelial cells
    • Holtzman, M.J., Turk, J. & Shornick, L.P. (1992). Identification of a pharmacologically distinct prostaglandin H synthase in cultured epithelial cells. J. Biol. Chem., 267, 21438-21445.
    • (1992) J. Biol. Chem. , vol.267 , pp. 21438-21445
    • Holtzman, M.J.1    Turk, J.2    Shornick, L.P.3
  • 13
    • 0026584898 scopus 로고
    • Nitric oxide, an inhibitor of lipid oxidation by lipoxygenase, cyclooxygenase and hemoglobin
    • Kanner, J., Harel, S. & Granit, R. (1992). Nitric oxide, an inhibitor of lipid oxidation by lipoxygenase, cyclooxygenase and hemoglobin. Lipids, 27, 46-49.
    • (1992) Lipids , vol.27 , pp. 46-49
    • Kanner, J.1    Harel, S.2    Granit, R.3
  • 14
    • 0026526828 scopus 로고
    • Increased excretion of leukotriene E4 during aspirin-induced asthma
    • Knapp, H.R., Sladek, K. & Fitzgerald, G.A. (1992). Increased excretion of leukotriene E4 during aspirin-induced asthma. J. Lab. Clin. Med., 119, 48-51.
    • (1992) J. Lab. Clin. Med. , vol.119 , pp. 48-51
    • Knapp, H.R.1    Sladek, K.2    Fitzgerald, G.A.3
  • 17
    • 0034746479 scopus 로고    scopus 로고
    • Effects of prostaglandin E2 and cAMP elevating drugs on GM-CSF release by cultured human airway smooth muscle cells. Relevance to asthma therapy
    • Lazzeri, N., Belvisi, M.G., Patel, H.J., Yacoub, M.H., Fan Chung, K. & Mitchell, J.A. (2001). Effects of prostaglandin E2 and cAMP elevating drugs on GM-CSF release by cultured human airway smooth muscle cells. Relevance to asthma therapy. Am. J. Respir. Cell. Mol. Biol., 24, 44-48.
    • (2001) Am. J. Respir. Cell. Mol. Biol. , vol.24 , pp. 44-48
    • Lazzeri, N.1    Belvisi, M.G.2    Patel, H.J.3    Yacoub, M.H.4    Fan Chung, K.5    Mitchell, J.A.6
  • 18
    • 0032860590 scopus 로고    scopus 로고
    • Means of increasing sensitivity of an in vitro diagnostic test for aspirin intolerance
    • May, A., Weber, A., Gall, H., Kaufmann, R. & Zollner, T.M. (1999). Means of increasing sensitivity of an in vitro diagnostic test for aspirin intolerance. Clin. Exp. Allergy, 29, 1402-1411.
    • (1999) Clin. Exp. Allergy , vol.29 , pp. 1402-1411
    • May, A.1    Weber, A.2    Gall, H.3    Kaufmann, R.4    Zollner, T.M.5
  • 19
    • 0030733844 scopus 로고    scopus 로고
    • Too many COX (cyclooxygenase) spoil the broth: Aspirin-sensitive asthma and 5-lypoxygenase
    • Mitchell, J.A. & Belvisi, M.G. (1997). Too many COX (cyclooxygenase) spoil the broth: Aspirin-sensitive asthma and 5-lypoxygenase. Thorax, 52, 933-935.
    • (1997) Thorax , vol.52 , pp. 933-935
    • Mitchell, J.A.1    Belvisi, M.G.2
  • 21
    • 0030976878 scopus 로고    scopus 로고
    • Sodium salicylate inhibits cyclo-oxygenase-2 activity independently of transcription factor (nuclear factor kappaB) activation: Role of arachidonic acid
    • Mitchell, J.A., Saunders, M., Barnes, P.J., Newton, R. & Belvisi, M.G. (1997). Sodium salicylate inhibits cyclo-oxygenase-2 activity independently of transcription factor (nuclear factor kappaB) activation: Role of arachidonic acid. Mol. Pharmacol., 51, 907-912.
    • (1997) Mol. Pharmacol. , vol.51 , pp. 907-912
    • Mitchell, J.A.1    Saunders, M.2    Barnes, P.J.3    Newton, R.4    Belvisi, M.G.5
  • 22
    • 0032737556 scopus 로고    scopus 로고
    • Cyclo-oxygenase-2: Pharmacology, physiology, biochemistry and relevance to NSAID therapy
    • Mitchell, J.A. & Warner, T.D. (1999). Cyclo-oxygenase-2: Pharmacology, physiology, biochemistry and relevance to NSAID therapy. Br. J. Pharmacol., 128, 1121-1132.
    • (1999) Br. J. Pharmacol. , vol.128 , pp. 1121-1132
    • Mitchell, J.A.1    Warner, T.D.2
  • 24
    • 0034530383 scopus 로고    scopus 로고
    • A moderate and unspecific release of cysteinyl leukotrienes by aspirin from peripheral blood leukocytes precludes its value for aspirin sensitivity testing in asthma
    • Pierzchalska, M., Mastalerz, L., Sanak, M., Zazula, M. & Szczeklik, A. (2000). A moderate and unspecific release of cysteinyl leukotrienes by aspirin from peripheral blood leukocytes precludes its value for aspirin sensitivity testing in asthma. Clin. Exp. Allergy, 30, 1785-1791.
    • (2000) Clin. Exp. Allergy , vol.30 , pp. 1785-1791
    • Pierzchalska, M.1    Mastalerz, L.2    Sanak, M.3    Zazula, M.4    Szczeklik, A.5
  • 25
  • 26
    • 0030781483 scopus 로고    scopus 로고
    • Enhanced expression of cyclo-oxygenase isoenzyme 2 (COX-2) in asthmatic airways and its cellular distribution in aspirin-sensitive asthma
    • Sousa, A., Pfister, R., Christie, P.E., Lane, S.J., Nasser, S.M., Schmitz-Schumann, M. & Lee, T.H. (1997). Enhanced expression of cyclo-oxygenase isoenzyme 2 (COX-2) in asthmatic airways and its cellular distribution in aspirin-sensitive asthma. Thorax, 52, 940-945.
    • (1997) Thorax , vol.52 , pp. 940-945
    • Sousa, A.1    Pfister, R.2    Christie, P.E.3    Lane, S.J.4    Nasser, S.M.5    Schmitz-Schumann, M.6    Lee, T.H.7
  • 28
    • 0031819750 scopus 로고    scopus 로고
    • Effect of nitric oxide-releasing aspirin derivative on gastric functional and ulcerogenic responses in rats: Comparison with plain aspirin
    • Takeuchi, K., Ukawa, H., Konaka, A. Kitamura, M. & Sugawa, Y. (1998). Effect of nitric oxide-releasing aspirin derivative on gastric functional and ulcerogenic responses in rats: Comparison with plain aspirin. J. Pharmacol. Exp. Ther., 286, 115-121.
    • (1998) J. Pharmacol. Exp. Ther. , vol.286 , pp. 115-121
    • Takeuchi, K.1    Ukawa, H.2    Konaka, A.3    Kitamura, M.4    Sugawa, Y.5
  • 29
    • 0029900395 scopus 로고    scopus 로고
    • Effects of theophylline and rolipram on leukotriene C4 (LTC4) synthesis and chemotaxis of human eosinophils from normal and atopic subjects
    • Tenor, H., Hatzelmann, A., Church, M.K., Schudt, C. & Shute, J.K. (1996). Effects of theophylline and rolipram on leukotriene C4 (LTC4) synthesis and chemotaxis of human eosinophils from normal and atopic subjects. Br. J. Pharmacol., 118, 1727-1735.
    • (1996) Br. J. Pharmacol. , vol.118 , pp. 1727-1735
    • Tenor, H.1    Hatzelmann, A.2    Church, M.K.3    Schudt, C.4    Shute, J.K.5
  • 30
    • 0034699923 scopus 로고    scopus 로고
    • Nomenclature for COX-2 inhibitors
    • Vane, J.R. & Warner, T.D. (2000). Nomenclature for COX-2 inhibitors. Lancet, 356, 1373-1374.
    • (2000) Lancet , vol.356 , pp. 1373-1374
    • Vane, J.R.1    Warner, T.D.2
  • 31
    • 0033594911 scopus 로고    scopus 로고
    • Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: A full in vitro analysis
    • Warner, T.D., Giuliano, F., Vojnovic, I., Bukasa, A., Mitchell, J.A. & Vane, J.R. (1999). Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: A full in vitro analysis. Proc. Natl. Acad. Sci. U.S.A., 96, 7563-7568.
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 7563-7568
    • Warner, T.D.1    Giuliano, F.2    Vojnovic, I.3    Bukasa, A.4    Mitchell, J.A.5    Vane, J.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.