Comparative study of the repair kinetics of chromosomal aberrations and DNA strand breaks in proliferating and quiescent CHO cells

International Journal of Radiation Biology

Volumn 70, Issue 1, 1996, Pages 33-43

  Greinert, R ^a   Volkmer, B ^a   Virsik Peuckert, R P ^a   Harder, D ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CHO CELL; CHROMOSOME ABERRATION; CONTROLLED STUDY; DNA STRAND BREAKAGE; GAMMA RADIATION; PRIORITY JOURNAL; RADIATION INJURY REPAIR;

ANIMALS; CHO CELLS; CHROMOSOME ABERRATIONS; CRICETINAE; DNA DAMAGE; DNA REPAIR; KINETICS;

ANIMALIA;

EID: 0029902195     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/095530096145300     Document Type: Article

References (51)

1. AHNSTRÖM, G., and EDVARDSSON, K.-A., 1974, Radiation-induced single-strand breaks in DNA determined by rate of alkaline strand separation and hydroxylapatite chromatography: an alternative to velocity sedimentation. International Journal of Radiation Biology, 26, 493-497.
2. ALPER, T., 1977, Elkind recovery and 'sub-lethal' damage: a misleading association? British Journal of Radiology, 50, 459-467.
3. BAISCH, H., LINDEN, W.H., and WEIGERT, H. D., 1977, Effects of Daunomycin and radiation on cell-survival and repair of DNA single-strand breaks. International Journal of Radiation Biology, 32, 209-218.
4. BEN-HUR, E., and ELKIND, M. M., 1974, Thermally enhanced radioresponse of cultured Chinese hamster cells: damage and repair of single-stranded DNA and a DNA complex. Radiation Research, 59, 484-495.
5. BILL, C. A., GORCHAN, B. M., VRDOLJAK, E., MENDOZA, E. A., and TOFILON, P. J., 1992, Decreased repair of radiation-induced DNA double-strand breaks with cellular differentiation. Radiation Research, 132, 254-258.
6. BOERRIGTER, M. E. T. I., and VIJG, J., 1992, Single-strand break disappearance in quiescent and phytohaemagglutinine-stimulated human peripheral blood lymphocytes exposed to a single low dose γ-irradiation. International Journal of Radiation Biology, 61, 95-101.
7. BRYANT, P. E., 1988, Use of restriction endonucleases to study relationships between DNA double strand breaks, chromosomal aberrations and other end points in mammalian cells. International Journal of Radiation Biology, 54, 869-890.
8. BRYANT, P. E., and BLÖCHER, P. E., 1980, Measurement of the kinetics of DNA double strand break repair in Ehrlich ascites tumour cells using the unwinding method. International Journal of Radiation Biology, 38, 335-347.
9. CALDECOTT, K., BANKS, G., and JEGGO, P., 1991), DNA double-strand break repair pathways and cellular tolerance to inhibitors of Topoisomerase II. Cancer Research, 50, 5778-5783.
10. DAHM-DAPHI., J., DIKOMEY, E., PYTTLIK, C., and JEGGO, P. A., 1993, Repairable and nonrepairable DNA strand breaks induced by X-irradiation in CHO K1 cells and the radiosensitive mutants xrs1 and xrs5. International Journal of Radiation Biology, 64, 19-26.
11. DIKOMEY, E., and FRANZKE, J., 1986a, Three classes of DNA strand breaks induced by X-irradiation and internal β-rays. International Journal of Radiation Biology, 50, 893-908.
12. DIKOMEY, E., and FRANZKE, J., 1986b, DNA repair kinetics after exposure to X-irradiation and Io internal β-rays in CHO cells. Radiation and Environmental Biophysics, 25, 189-194.
13. DIKOMEY, K., FLENTJE, M., and DAHM-DAPHI, J., 1995, Comparison between the alkali unwinding technique and neutral filter elution using CHO, V79 and EAT cells. International Journal of Radiation Biology, 67, 269-275.
14. ELLA, M. C., DE LUCA, J. G., and BRADLEY, M. O., 1991, Significance and measurement of DNA double strand breaks in mammalian cells. Pharmacological Therapy, 51, 291-327.
15. EVANS, H. J., 1977, Molecular mechanism in the induction of chromosome aberrations. In Progress in Genetic Toxicology, edited by D. Scott, B. A. Bridges and F. M. Sobels (Elsevier/North-Holland Biomedical Press: Amsterdam), pp. 57-71.
16. FRANKENBERG-SCHWAGER, M., 1989, Review of repair kinetics for DNA damage induced in eukaryotic cells in vitro by ionizing radiation. Radiotherapy and Oncology, 14, 307-320.
17. GOODHEAD, D. T., 1994, Initial events in the cellular effects of ionizing radiations: clustered damage in DNA. International Journal of Radiation Biology, 65, 7-17.
18. GREINERT, R., DETZLER, E., VOLKMER, B., and HARDER, D., 1995, Kinetics of chromosome aberration formation in X-irradiated human lymphocytes: analysis by delay-time PCC experiments. Radiation Research, 144, 190-197.
19. GREINERT, R., BOGUHN, O., VOLKMER, B., and HARDER, D., 1996, UV-sensitivity of CHO xrs5 cells is due to a deficiency in nucleotide excision repair. A flow cytometric study (in preparation).
20. HAGENAH, B., 1995, Anwendung der digitalen Bildverarbeitung zur Auswertung von Ergebnissen der Pulsfeld-Gelelektrophorese bei der Untersuchung strahleninduzierter DNA-Schäden. Diploma thesis, University of Göttingen.
21. HARDER, D., and VIRSIK-PEUCKERT, P., 1984, Kinetics of cell survival as predicted by the repair/interaction model. British Journal of Cancer, 49 (suppl. VI), 243-247.
22. HARDER, D., VIRSIK-PEUCKERT, P., and BARTELS, E., 1992, Theory of pairwise lesion interactions. In Biophysical Modelling of Radiation Effects, edited by K. H. Chadwick, G. Moschini and M. N. Varma (Bristol: A. Hilger), pp. 179-184.
23. HOLLEY, W. R., and CHATTERJEE, A., 1996, Clusters of DNA damage induced by ionizing radiation: Formation of short DNA fragments. I. Theoretical modeling. Radiation Research, 145, 188-199.
24. 1-phase CHO cells. International Journal of Radiation Biology, 52, 705-722.
25. ILIAKIS, G., PANTELIAS, G., and SEANER, R., 1988, Effect of arabinofuranosyladenine on radiation-induced chromosome damage in plateau phase CHO cells measured by premature chromosome condensation: implications for repair and fixation of α-PLD. Radiation Research, 114, 361-378.
26. ILIAKIS, G., BLÖCHER, D., METZGER, L., and PANTELIAS, G., 1991, Comparison of DNA double-strand break rejoining as measured by pulsed field gel electrophoresis, neutral sucrose gradient centrifugation and non-unwinding filter elution in irradiated plateau-phase CHO cells. International Journal of Radiation Biology, 59, 927-939.
27. ILIAKIS, G., MEHTA, R., and JACKSON, M., 1992, Level of DNA double-strand break rejoining in Chinese hamster xrs-5 cells is dose-dependent: implications for the mechanism of radiosensitivity. International Journal of Radiation Biology, 91, 315-321.
28. ILIAKIS, G., OKAYASU, R., VARLOTTO, J., SHERNOFF, C., and WANG, Y., 1993, Hypertonic treatment during premature chromosome condensation allows visualization of interphase chromosome breaks repaired with fast kinetics in irradiated CHO cells. Radiation Research, 135, 160-170.
29. JHA, B., and POHLIT, W., 1993, Reversibility of inhibition of DNA double-strand break repair by 2-deoxy-D-glucose in Ehrlich ascites tumour cells. International Journal of Radiation Biology, 63, 459-467.
30. KUBOTA, N., and HILL, C. K., 1988, Repair of potentially mutagenic damage, sensitive to anisotonic treatment, in active growing Chinese hamster cells. International Journal of Radiation Biology, 54, 221-228.
31. KYSELA, B. P., MICHAEL, B. O., and ARRAND, J. E., 1993, Relative contributions of levels of initial DNA damage and repair of double strand breaks to the ionizing radiation-sensitive phenotype of the Chinese hamster cell mutant XR-V15 B. Part I. X-rays. International Journal of Radiation Biology, 63, 609-616.
32. METZGER, I., and ILIAKIS, G., 1991, Kinetics of DNA double-strand break repair throughout the cell cycle as assayed by pulsed field gel electrophoresis in CHO cells. International Journal of Radiation Biology, 59, 1325-1339.
33. NATARAJAN, A. T., and OBE, G., 1984, Molecular mechanisms involved in the production of chromosomal aberrations III. Restriction endonucleases. Chromosoma, 90, 120-127.
34. NATARAJAN, A. T., DARROUDI, F., JHA, A. N., MEIJERS, M., and ZDZIENICKA, M. Z., 1993, Ionizing radiation induced DNA lesions which lead to chromosomal aberrations. Mutation Research, 299, 297-303.
35. OLIVE, P. L., WLODEK, D., and BANATH, J., 1991, DNA double strand breaks measured in individual cells subjected to gel electrophoresis. Cancer Research, 51, 4671-4676.
36. RESNICK, M. A., and MOORE, P. D., 1979, Molecular recombination and the repair of DNA double strand breaks in CHO cells. Nucleic Acids Research, 6, 3145-3160.
37. REVELL, S. H., 1966, Evidence for a dose-squared term in the dose-response curve for real chromatid discontinuities induced by X-rays, and some theoretical consequences thereof. Mutation Research, 3, 34-53.
38. ROTH, B. D., PORTER, Th. N., and WILSON, J. H., 1985, Mechanisms of nonhomologous recombination in mammalian cells. Molecular and Cellular Biology, 5, 2599-2607.
39. RYDBERG, B., 1975, The rate of strand separation in alkali of DNA of irradiated mammalian cells. Radiation Research, 61, 274-287,
40. RYDBERG, B., HOLLEY, W. R., and CHATTERJEE, A., 1995, Regionally multiply damaged sites: theoretical and experimental evidence. In Radiation Damage in DNA. Structure/Function Relationships at Early Times, edited by A. F. Fuciarelli and J. D. Zimbrick (Batelle: Columbus), pp. 55-63.
41. RYDBERG, B., 1996, Clusters of DNA damage induced by ionizing radiation: Formation of short I)NA fragments. II. Experimental Detection. Radiation Research, 145, 200-209.
42. SCOTT, D., and ZAMPETTI-BOSSELER, F., 1980, The relationship between cell killing, chromosome aberrations, spindle defects and mitotic delay in mouse lymphoma cells of differential sensitivity to X-rays. International Journal of Radiation Biology, 37, 33-47.
43. UTSUMI, H., and ELKIND, M. M., 1979, Potentially lethal damage versus sublethal damage: independent repair processes in actively growing Chinese hamster cells. Radiation Research, 77, 346-360.
44. VAN DER SCHAANS, G. P., VAN LOON, A. A. W. M., GROENENDIJK, R. H., and BAAN, R. A., 1989, Detection of DNA damage in cells exposed to ionizing radiation by use of anti-single-stranded DNA monoclonal antibody. International Journal of Radiation Biology, 55, 747-750.
45. 0 lymphocytes. Radiation and Environmental Biophysics, 18, 221-238.
46. VIRSIK-PEUCKERT, R. P., VOLKMER, B., and MEHMEL, D., 1995, Influence of ara A on the radiation-induced repair process in Chinese hamster cells studied at the level of chromosome aberrations. International Journal of Radiation Biology, 68, 235-244.
47. VOLKMER, B., and VIRSIK-PEUCKERT, R. P., 1990. Kinetics of chromosome lesion repair in synchronized quiescent and proliferating CHO cells. International Journal of Radiation Biology, 58, 1009-1023.
48. WEIBEZAHN, K. F., and COQUERELLE, T., 1981, Radiation induced DXA double strand breaks are rejoined by ligation and recombination processes. Nucleic Acids Research, 9, 3139-3150.
49. 2 block in Chinese hamster ovary cells and their radiosensitive mutants. Mutation Research, 145, 177-183.
50. WINEGAR, R. A., and PRESTON, R. Y., 1988, The induction of chromosome aberrations by restriction endonucleases that produce blunt-end or cohesive-end double-strand breaks. Mutation Research, 197, 141-149.
51. ZHANG, S., and DONG, W., 1987, Chromosomal aberrations induced by restriction endonucleases EcoRI, PstI, SalI and BamHI in CHO-cells. Mutation Research, 180, 109-114.