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Volumn 100, Issue 12, 2002, Pages 4019-4025

Differential regulation of the von Willebrand factor and Flt-1 promoters in the endothelium of hypoxanthine phosphoribosyltransferase-targeted mice

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MESSENGER RNA; PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 1; VON WILLEBRAND FACTOR;

EID: 0036892730     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2002-03-0955     Document Type: Article
Times cited : (34)

References (44)
  • 1
    • 0032525207 scopus 로고    scopus 로고
    • Endothelial cells in physiology and in the pathophysiology of vascular disorders
    • Cines DB, Pollak ES, Buck CA, et al. Endothelial cells in physiology and in the pathophysiology of vascular disorders. Blood. 1998;91:3527-3561.
    • (1998) Blood , vol.91 , pp. 3527-3561
    • Cines, D.B.1    Pollak, E.S.2    Buck, C.A.3
  • 2
    • 0033586986 scopus 로고    scopus 로고
    • Vascular-bed-specific hemostasis and hypercoagulable states
    • Rosenberg RD, Aird WC. Vascular-bed-specific hemostasis and hypercoagulable states. N Engl J Med. 1999;340:4556-1664.
    • (1999) N Engl J Med , vol.340 , pp. 1556-1664
    • Rosenberg, R.D.1    Aird, W.C.2
  • 3
    • 0028990234 scopus 로고
    • Human von Willebrand factor gene sequences target expression to a subpopulation of endothelial cells in transgenic mice, Proc Natl Acad Sci U S A
    • Aird WC, Jahroudi N, Weiler-Guettler H, Rayburn HB, Rosenberg RD. Human von Willebrand factor gene sequences target expression to a subpopulation of endothelial cells in transgenic mice, Proc Natl Acad Sci U S A. 1995;92:4567-4571.
    • (1995) , vol.92 , pp. 4567-4571
    • Aird, W.C.1    Jahroudi, N.2    Weiler-Guettler, H.3    Rayburn, H.B.4    Rosenberg, R.D.5
  • 4
    • 0030885145 scopus 로고    scopus 로고
    • Vascular bed-specific expression of an endothetial cell gene is programmed by the tissue microenvironment
    • Aird WC, Edelberg JM, Weiler-Guettler H, et al. Vascular bed-specific expression of an endothetial cell gene is programmed by the tissue microenvironment. J Cell Biol. 1997;138:1117-1124.
    • (1997) J Cell Biol , vol.138 , pp. 1117-1124
    • Aird, W.C.1    Edelberg, J.M.2    Weiler-Guettler, H.3
  • 5
    • 0033560056 scopus 로고    scopus 로고
    • A vascular bed-specific pathway
    • Guiliot PV, Guan J, Liu L, et al. A vascular bed-specific pathway. J Clin Invest. 1999;103:799-805.
    • (1999) J Clin Invest , vol.103 , pp. 799-805
    • Guiliot, P.V.1    Guan, J.2    Liu, L.3
  • 6
    • 0033810440 scopus 로고    scopus 로고
    • The Egr-1 promoter contains information for constitutive and inducible expression in transgenic mice
    • Tsai JC, Liu L, Cooley BC, et al. The Egr-1 promoter contains information for constitutive and inducible expression in transgenic mice. FASEB J. 2000;14:1870-1872.
    • (2000) FASEB J , vol.14 , pp. 1870-1872
    • Tsai, J.C.1    Liu, L.2    Cooley, B.C.3
  • 7
    • 0029132968 scopus 로고
    • Endothelial-specific gene expression directed by the tie gene promoter in vivo
    • Korhonen J, Lahtinen I, Halmekyto M, et al. Endothelial-specific gene expression directed by the tie gene promoter in vivo. Blood. 1995;86:1828-1835.
    • (1995) Blood , vol.86 , pp. 1828-1835
    • Korhonen, J.1    Lahtinen, I.2    Halmekyto, M.3
  • 8
    • 0028943808 scopus 로고
    • Vascular endothelial cell lineage-specific promoter in transgenic mice
    • Schlaeger TM, Qin Y, Fujiwara Y, Magram J, Sato TN. Vascular endothelial cell lineage-specific promoter in transgenic mice. Development. 1995; 121:1089-1098.
    • (1995) Development , vol.121 , pp. 1089-1098
    • Schlaeger, T.M.1    Qin, Y.2    Fujiwara, Y.3    Magram, J.4    Sato, T.N.5
  • 9
    • 0032961884 scopus 로고    scopus 로고
    • The vascular endothelial-cadherin promoter directs endothelial-specific expression in transgenic mice
    • Gory S, Vernet M, Laurent M, et al. The vascular endothelial-cadherin promoter directs endothelial-specific expression in transgenic mice. Blood. 1999;93:184-192.
    • (1999) Blood , vol.93 , pp. 184-192
    • Gory, S.1    Vernet, M.2    Laurent, M.3
  • 10
    • 0028918281 scopus 로고
    • Targeting gene expression to the vascular wall in transgenic mice using the murine preproendothelin-1 promoter
    • Harats D, Kurihara H, Belloni P, et al. Targeting gene expression to the vascular wall in transgenic mice using the murine preproendothelin-1 promoter. J Clin Invest. 1995;95:1335-1344.
    • (1995) J Clin Invest , vol.95 , pp. 1335-1344
    • Harats, D.1    Kurihara, H.2    Belloni, P.3
  • 11
    • 0034642777 scopus 로고    scopus 로고
    • Targeting of human eNOS promoter to the Hprt locus of mice leads to tissue-restricted transgene expression
    • Guillot PV, Liu L, Kuivenhoven JA, et al. Targeting of human eNOS promoter to the Hprt locus of mice leads to tissue-restricted transgene expression. Physiol Genomics. 2000;2:77-83.
    • (2000) Physiol Genomics , vol.2 , pp. 77-83
    • Guillot, P.V.1    Liu, L.2    Kuivenhoven, J.A.3
  • 12
    • 0034642768 scopus 로고    scopus 로고
    • Targeting the Hprt locus in mice reveals differential regulation of Tie2 gene expression in the endothelium
    • Evans V, Hatzopoulos A, Aird WC, et al. Targeting the Hprt locus in mice reveals differential regulation of Tie2 gene expression in the endothelium. Physiol Genomics. 2000;2:67-75.
    • (2000) Physiol Genomics , vol.2 , pp. 67-75
    • Evans, V.1    Hatzopoulos, A.2    Aird, W.C.3
  • 13
    • 0035861596 scopus 로고    scopus 로고
    • Thrombin stimulation of the vascular cell adhesion molecule-1 promoter in endothelial cells is mediated by tandem nuclear factor-kappa B and GATA motifs
    • Minami T, Aird WC. Thrombin stimulation of the vascular cell adhesion molecule-1 promoter in endothelial cells is mediated by tandem nuclear factor-kappa B and GATA motifs. J Biol Chem. 2001;276:47632-47641.
    • (2001) J Biol Chem , vol.276 , pp. 47632-47641
    • Minami, T.1    Aird, W.C.2
  • 15
    • 0028880451 scopus 로고
    • A novel promoter for vascular endothelial growth factor receptor (flt-1) that confers endothelial-specific gene expression
    • Morishita K, Johnson DE, Williams LT. A novel promoter for vascular endothelial growth factor receptor (flt-1) that confers endothelial-specific gene expression. J Biol Chem. 1995;270:27948-27953.
    • (1995) J Biol Chem , vol.270 , pp. 27948-27953
    • Morishita, K.1    Johnson, D.E.2    Williams, L.T.3
  • 16
    • 0025933332 scopus 로고
    • Angioblast differentiation and morphogenesis of the vascular endothelium in the mouse embryo
    • Coffin JD, Harrison J, Schwartz S, Heimark R. Angioblast differentiation and morphogenesis of the vascular endothelium in the mouse embryo. Dev Biol. 1991;148:51-62.
    • (1991) Dev Biol , vol.148 , pp. 51-62
    • Coffin, J.D.1    Harrison, J.2    Schwartz, S.3    Heimark, R.4
  • 17
    • 0032529104 scopus 로고    scopus 로고
    • PDGF mediates cardiac microvascular communication
    • Edelberg JM, Aird WC, Wu W, et al. PDGF mediates cardiac microvascular communication. J Clin Invest. 1998;102:837-843.
    • (1998) J Clin Invest , vol.102 , pp. 837-843
    • Edelberg, J.M.1    Aird, W.C.2    Wu, W.3
  • 18
    • 0027432324 scopus 로고
    • Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumor angiogenesis
    • Plate KH, Breier G, Millauer B, Ullrich A, Risau W. Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumor angiogenesis. Cancer Res. 1993; 53:5822-5827.
    • (1993) Cancer Res , vol.53 , pp. 5822-5827
    • Plate, K.H.1    Breier, G.2    Millauer, B.3    Ullrich, A.4    Risau, W.5
  • 19
    • 0034913357 scopus 로고    scopus 로고
    • Vascular bed-specific hemostasis: Role of endothelium in sepsis pathogenesis
    • Aird WC. Vascular bed-specific hemostasis: Role of endothelium in sepsis pathogenesis. Crit Care Med. 2001;29:S28-S35.
    • (2001) Crit Care Med , vol.29
    • Aird, W.C.1
  • 20
    • 0033571291 scopus 로고    scopus 로고
    • Characterization of the mouse von Willebrand factor promoter
    • Guan J, Guillot PV, Aird WC. Characterization of the mouse von Willebrand factor promoter. Blood. 1999;94:3405-3412.
    • (1999) Blood , vol.94 , pp. 3405-3412
    • Guan, J.1    Guillot, P.V.2    Aird, W.C.3
  • 21
    • 0026572345 scopus 로고
    • The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor
    • de Vries C, Escobedo JA, Ueno H, et al. The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science. 1992;255:989-991.
    • (1992) Science , vol.255 , pp. 989-991
    • De Vries, C.1    Escobedo, J.A.2    Ueno, H.3
  • 22
    • 0026702970 scopus 로고
    • Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor
    • Terman BI, Dougher-Vermazen M, Carrion ME, et at. Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor. Biochem Biophys Res Commun. 4992;187: 1579-1586.
    • (1992) Biochem Biophys Res Commun , vol.187 , pp. 1579-1586
    • Terman, B.I.1    Dougher-Vermazen, M.2    Carrion, M.E.3
  • 23
    • 0029021660 scopus 로고
    • Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
    • Fong GH, Rossant J, Gertsenstein M, Breitman ML. Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature. 1995;376:66-70.
    • (1995) Nature , vol.376 , pp. 66-70
    • Fong, G.H.1    Rossant, J.2    Gertsenstein, M.3    Breitman, M.L.4
  • 24
    • 0032482978 scopus 로고    scopus 로고
    • Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice
    • Hiratsuka S, Minowa O, Kuno J, Noda T, Shibuya M. Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice. Proc Natl Acad Sci U S A. 1998;95:9349-9354.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 9349-9354
    • Hiratsuka, S.1    Minowa, O.2    Kuno, J.3    Noda, T.4    Shibuya, M.5
  • 25
    • 0034610077 scopus 로고    scopus 로고
    • Mouse flt-1 promoter directs endothelial-specific expression in the embyroid body model of embryogenesis
    • Quinn G, Ochiya T, Terada M, Yoshida T. Mouse flt-1 promoter directs endothelial-specific expression in the embyroid body model of embryogenesis. Biochem Biophys Res Commun. 2000;276: 1089-1099.
    • (2000) Biochem Biophys Res Commun , vol.276 , pp. 1089-1099
    • Quinn, G.1    Ochiya, T.2    Terada, M.3    Yoshida, T.4
  • 26
    • 0029862405 scopus 로고    scopus 로고
    • Characterization of the promoter region for flt-1 tyrosine kinase gene, a receptor for vascular endothelial growth factor
    • Ikeda T, Wakiya K, Shibuya M. Characterization of the promoter region for flt-1 tyrosine kinase gene, a receptor for vascular endothelial growth factor. Growth Factors. 1996;13:151-162.
    • (1996) Growth Factors , vol.13 , pp. 151-162
    • Ikeda, T.1    Wakiya, K.2    Shibuya, M.3
  • 27
    • 0029807470 scopus 로고    scopus 로고
    • A cAMP response element and an Ets motif are involved in the transcriptional regulation of flt-1 tyrosine kinase (vascular endothelial growth factor receptor 1) gene
    • Wakiya K, Begue A, Stehelin D, Shibuya M. A cAMP response element and an Ets motif are involved in the transcriptional regulation of flt-1 tyrosine kinase (vascular endothelial growth factor receptor 1) gene. J Biol Chem. 1996;271:30823-30828.
    • (1996) J Biol Chem , vol.271 , pp. 30823-30828
    • Wakiya, K.1    Begue, A.2    Stehelin, D.3    Shibuya, M.4
  • 28
    • 0034210253 scopus 로고    scopus 로고
    • Up-regulation of vascular endothelial growth factor receptor Flt-1 after endothelial denudation: Role of transcription factor Egr-1
    • Vidal, F, Aragones J, Alfranca A, de Landazuri MO. Up-regulation of vascular endothelial growth factor receptor Flt-1 after endothelial denudation: Role of transcription factor Egr-1. Blood. 2000;95: 3387-3395.
    • (2000) Blood , vol.95 , pp. 3387-3395
    • Vidal, F.1    Aragones, J.2    Alfranca, A.3    De Landazuri, M.O.4
  • 29
    • 0035190838 scopus 로고    scopus 로고
    • Spatiotemporal expression of angiogenesis growth factor receptors during the revascularization of regenerating rat liver
    • Ross MA, Sander CM, Kleeb TB, Watkins SC, Stolz DB. Spatiotemporal expression of angiogenesis growth factor receptors during the revascularization of regenerating rat liver. Hepatology. 2001;34:1135-1148.
    • (2001) Hepatology , vol.34 , pp. 1135-1148
    • Ross, M.A.1    Sander, C.M.2    Kleeb, T.B.3    Watkins, S.C.4    Stolz, D.B.5
  • 30
    • 0030568858 scopus 로고    scopus 로고
    • Increased expressions of vascular endothelial growth factor and its receptors, flt-1 and KDR/flk-1, in regenerating rat liver
    • Mochida S, Ishikawa K, Inao M, Shibuya M, Fujiwara K. Increased expressions of vascular endothelial growth factor and its receptors, flt-1 and KDR/flk-1, in regenerating rat liver. Biochem Biophys Res Commun. 1996;226:176-179.
    • (1996) Biochem Biophys Res Commun , vol.226 , pp. 176-179
    • Mochida, S.1    Ishikawa, K.2    Inao, M.3    Shibuya, M.4    Fujiwara, K.5
  • 31
    • 0037065850 scopus 로고    scopus 로고
    • Systemic production of vascular endothelial growth factor and fms-like tyrosine kinase-1 receptor in acute Kawasaki disease
    • Yasukawa K, Terai M, Shulman ST, et al. Systemic production of vascular endothelial growth factor and fms-like tyrosine kinase-1 receptor in acute Kawasaki disease. Circulation. 2002;105: 766-769.
    • (2002) Circulation , vol.105 , pp. 766-769
    • Yasukawa, K.1    Terai, M.2    Shulman, S.T.3
  • 32
    • 0344705115 scopus 로고    scopus 로고
    • VEGF, flk-1, and flt-1 expression in a rat myocardial infarction model of angiogenesis
    • Li J, Brown LF, Hibberd MG, et al. VEGF, flk-1, and flt-1 expression in a rat myocardial infarction model of angiogenesis. Am J Physiol. 1996;270: H1803-H1811.
    • (1996) Am J Physiol , vol.270
    • Li, J.1    Brown, L.F.2    Hibberd, M.G.3
  • 33
    • 0028090642 scopus 로고
    • Vascular endothelial growth factor and glioma angiogenesis: Coordinate induction of VEGF receptors, distribution of VEGF protein and possible in vivo regulatory mechanisms
    • Plate KH, Breier G, Weich HA, Mennel HD, Risau W. Vascular endothelial growth factor and glioma angiogenesis: Coordinate induction of VEGF receptors, distribution of VEGF protein and possible in vivo regulatory mechanisms. Int J Cancer. 1994;59:520-529.
    • (1994) Int J Cancer , vol.59 , pp. 520-529
    • Plate, K.H.1    Breier, G.2    Weich, H.A.3    Mennel, H.D.4    Risau, W.5
  • 34
    • 0030806074 scopus 로고    scopus 로고
    • Up-regulation of vascular endothelial growth factor expression in a rat glioma is conferred by two distinct hypoxia-driven mechanisms
    • Damert A, Machein M, Breier G, et al. Up-regulation of vascular endothelial growth factor expression in a rat glioma is conferred by two distinct hypoxia-driven mechanisms. Cancer Res. 1997; 57:3860-3864.
    • (1997) Cancer Res , vol.57 , pp. 3860-3864
    • Damert, A.1    Machein, M.2    Breier, G.3
  • 35
    • 0027768808 scopus 로고
    • Increased expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in kidney and bladder carcinomas
    • Brown LF, Berse B, Jackman RW, et al. Increased expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in kidney and bladder carcinomas. Am J Pathol. 1993;143:1255-1262.
    • (1993) Am J Pathol , vol.143 , pp. 1255-1262
    • Brown, L.F.1    Berse, B.2    Jackman, R.W.3
  • 36
    • 0028935608 scopus 로고
    • Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis
    • Warren RS, Yuan H, Matli MR, Gillett NA, Ferrara N. Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis. J Clin Invest. 1995;95:1789-1797.
    • (1995) J Clin Invest , vol.95 , pp. 1789-1797
    • Warren, R.S.1    Yuan, H.2    Matli, M.R.3    Gillett, N.A.4    Ferrara, N.5
  • 37
    • 0034326809 scopus 로고    scopus 로고
    • Tumor endothelium-specific transgene expression directed by vascular endothelial growth factor receptor-2 (Flk-1) promoter/enhancer sequences
    • Heidenreich R, Kappel A, Breier G. Tumor endothelium-specific transgene expression directed by vascular endothelial growth factor receptor-2 (Flk-1) promoter/enhancer sequences. Cancer Res. 2000;60:6142-6147.
    • (2000) Cancer Res , vol.60 , pp. 6142-6147
    • Heidenreich, R.1    Kappel, A.2    Breier, G.3
  • 38
    • 0029147486 scopus 로고
    • Cloning and functional analysis of the promoter for KDR/flk-1, a receptor for vascular endothelial growth factor
    • Patterson C, Perrella MA, Hsieh CM, et al. Cloning and functional analysis of the promoter for KDR/flk-1, a receptor for vascular endothelial growth factor. J Biol Chem. 1995;270:23111-23118.
    • (1995) J Biol Chem , vol.270 , pp. 23111-23118
    • Patterson, C.1    Perrella, M.A.2    Hsieh, C.M.3
  • 39
    • 0030058001 scopus 로고    scopus 로고
    • Characterization of the endothelium-specific murine vascular endothelial growth factor receptor-2 (Flk-1) promoter
    • Ronicke V, Risau W, Breier G. Characterization of the endothelium-specific murine vascular endothelial growth factor receptor-2 (Flk-1) promoter. Circ Res. 1996;79:277-285.
    • (1996) Circ Res , vol.79 , pp. 277-285
    • Ronicke, V.1    Risau, W.2    Breier, G.3
  • 40
    • 0034717182 scopus 로고    scopus 로고
    • Homeostatic modulation of cell surface KDR and Flt1 expression and expression of the vascular endothelial cell growth factor (VEGF) receptor mRNAs by VEGF
    • Wang D, Donner DB, Warren RS. Homeostatic modulation of cell surface KDR and Flt1 expression and expression of the vascular endothelial cell growth factor (VEGF) receptor mRNAs by VEGF. J Biol Chem. 2000;275:15905-15911.
    • (2000) J Biol Chem , vol.275 , pp. 15905-15911
    • Wang, D.1    Donner, D.B.2    Warren, R.S.3
  • 41
    • 0030609013 scopus 로고    scopus 로고
    • Vascular endothelial growth factor up-regulates its receptor fms-like tyrosine kinase 1 (FLT-1) and a soluble variant of FLT-1 in human vascular endothelial cells
    • Barleon B, Siemeister G, Martiny-Baron G, et al. Vascular endothelial growth factor up-regulates its receptor fms-like tyrosine kinase 1 (FLT-1) and a soluble variant of FLT-1 in human vascular endothelial cells. Cancer Res. 1997;57:5421-5425.
    • (1997) Cancer Res , vol.57 , pp. 5421-5425
    • Barleon, B.1    Siemeister, G.2    Martiny-Baron, G.3
  • 42
    • 0030751493 scopus 로고    scopus 로고
    • Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes, Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia
    • Gerber HP, Condorelli F, Park J, Ferrara N. Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia. J Biol Chem. 1997;272:23659-23667.
    • (1997) J Biol Chem , vol.272 , pp. 23659-23667
    • Gerber, H.P.1    Condorelli, F.2    Park, J.3    Ferrara, N.4
  • 43
    • 0035053713 scopus 로고    scopus 로고
    • The Ets family contains transcriptional activators and repressors involved in angiogenesis
    • Lelievre E, Lionneton F, Soncin F, Vandenbunder B. The Ets family contains transcriptional activators and repressors involved in angiogenesis. Int J Biochem Cell Biol. 2001;33:391-407.
    • (2001) Int J Biochem Cell Biol , vol.33 , pp. 391-407
    • Lelievre, E.1    Lionneton, F.2    Soncin, F.3    Vandenbunder, B.4
  • 44
    • 0344578062 scopus 로고    scopus 로고
    • Expression of the Ets-1 transcription factor in human astrocytomas is associated with Fms-like tyrosine kinase-1 (Flt-1)/vascular endothelial growth factor receptor-1 synthesis and neoangiogenesis
    • Valter MM, Hugel A, Huang HJ, et al. Expression of the Ets-1 transcription factor in human astrocytomas is associated with Fms-like tyrosine kinase-1 (Flt-1)/vascular endothelial growth factor receptor-1 synthesis and neoangiogenesis. Cancer Res. 1999;59:5608-5614.
    • (1999) Cancer Res , vol.59 , pp. 5608-5614
    • Valter, M.M.1    Hugel, A.2    Huang, H.J.3


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