Transgenic mice expressing human interleukin-10 in the antigen-presenting cell compartment show increased susceptibility to infection with Mycobacterium avium associated with decreased macrophage effector function and apoptosis

Infection and Immunity

Volumn 70, Issue 12, 2002, Pages 6672-6679

  Feng, Carl G ^a   Kullberg, Marika C ^a   Jankovic, Dragana ^a   Cheever, Allen W ^b   Caspar, Patricia ^a   Coffman, Robert L ^c   Sher, Alan ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b BIOMEDICAL RESEARCH INSTITUTE   (United States)

^c Dynavax Technologies Corporation   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; NITRIC OXIDE; TUMOR NECROSIS FACTOR;

ACID FAST BACTERIUM; ANIMAL CELL; ANTIGEN PRESENTING CELL; APOPTOSIS; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; HOST RESISTANCE; IMMUNE RESPONSE; INFECTION SENSITIVITY; LIVER FIBROSIS; MACROPHAGE; MAJOR HISTOCOMPATIBILITY COMPLEX; MICROBIAL IMMUNITY; MOUSE; MYCOBACTERIOSIS; MYCOBACTERIUM AVIUM; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; TH1 CELL; TRANSGENIC MOUSE;

ANIMALS; ANTIGEN-PRESENTING CELLS; DISEASE SUSCEPTIBILITY; FEMALE; GRANULOMA; HUMANS; INTERLEUKIN-10; LIVER CIRRHOSIS; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; MYCOBACTERIUM AVIUM; TUBERCULOSIS;

EID: 0036892282     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.70.12.6672-6679.2002     Document Type: Article

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