메뉴 건너뛰기




Volumn 35, Issue 9, 2002, Pages 859-869

Rivastigmine: A review of its clinical effectiveness;Rivastigmina: Una revisión de su eficacia clínica

Author keywords

Activities of daily living; Alzheimer's disease; Cholinesterase inhibitors; Rivastigmine

Indexed keywords

ACETYLCHOLINE; CHOLINESTERASE INHIBITOR; DONEPEZIL; GALANTAMINE; PSYCHOTROPIC AGENT; RIVASTIGMINE;

EID: 0036860256     PISSN: 02100010     EISSN: None     Source Type: Journal    
DOI: 10.33588/rn.3509.2002002     Document Type: Conference Paper
Times cited : (6)

References (78)
  • 1
    • 0001791259 scopus 로고
    • Dementia of the Alzheimer type: Defining a disease
    • Bick KL, Katzman R, Terry RD, eds. New York: Raven Press
    • Terry R, Katzman R. Dementia of the Alzheimer type: Defining a disease. In Bick KL, Katzman R, Terry RD, eds. Alzheimer's Disease. New York: Raven Press; 1994. p. 51-84.
    • (1994) Alzheimer's Disease , pp. 51-84
    • Terry, R.1    Katzman, R.2
  • 2
    • 0030801772 scopus 로고    scopus 로고
    • Diagnosis and treatment of Alzheimer's disease and related disorders
    • Small GW, Rabins PV, Barry PP, et al. Diagnosis and treatment of Alzheimer's disease and related disorders. JAMA 1997; 278: 1363-71.
    • (1997) JAMA , vol.278 , pp. 1363-1371
    • Small, G.W.1    Rabins, P.V.2    Barry, P.P.3
  • 3
    • 0025911018 scopus 로고
    • Advances in Alzheimer's disease
    • Katzman R, Saitoh T. Advances in Alzheimer's disease. FASEB J 1991; 5: 278-86.
    • (1991) FASEB J , vol.5 , pp. 278-286
    • Katzman, R.1    Saitoh, T.2
  • 4
    • 0033604631 scopus 로고    scopus 로고
    • Treatment of Alzheimer's disease
    • Mayeux R, Sano M. Treatment of Alzheimer's disease. N Engl J Med 1999; 341: 1670-9.
    • (1999) N Engl J Med , vol.341 , pp. 1670-1679
    • Mayeux, R.1    Sano, M.2
  • 5
    • 0030954784 scopus 로고    scopus 로고
    • Alzheimer's disease: Cognitive and behavioral pharmacotherapy
    • Cummings JL, Mendez MF. Alzheimer's disease: Cognitive and behavioral pharmacotherapy. Conn Med 1997; 61: 543-2.
    • (1997) Conn Med , vol.61 , pp. 543-552
    • Cummings, J.L.1    Mendez, M.F.2
  • 6
    • 0024317904 scopus 로고
    • Prevalence of Alzheimer's disease in a community population of older persons. Higher than previously reported
    • Evans DA, Funkenstein HH, Albert MS, et al. Prevalence of Alzheimer's disease in a community population of older persons. Higher than previously reported. JAMA 1989; 262: 2551-6.
    • (1989) JAMA , vol.262 , pp. 2551-2556
    • Evans, D.A.1    Funkenstein, H.H.2    Albert, M.S.3
  • 8
    • 0034720816 scopus 로고    scopus 로고
    • Galantamine in AD: A 6-month randomized, placebo-controlled trial with a 6-month extension
    • The Galantamine USA-1 Study Group
    • Raskind MA, Peskind ER, Wessel T, Yuan W. Galantamine in AD: A 6-month randomized, placebo-controlled trial with a 6-month extension. The Galantamine USA-1 Study Group. Neurology 2000; 54: 2261-8.
    • (2000) Neurology , vol.54 , pp. 2261-2268
    • Raskind, M.A.1    Peskind, E.R.2    Wessel, T.3    Yuan, W.4
  • 9
    • 0034720864 scopus 로고    scopus 로고
    • A 5-month, randomized, placebo-controlled trial of galantamine in AD
    • Tariot PN, Solomon PR, Morris JC, et al, and The Galantamine USA-10 Study Group. A 5-month, randomized, placebo-controlled trial of galantamine in AD. Neurology 2000; 54: 2269-76.
    • (2000) Neurology , vol.54 , pp. 2269-2276
    • Tariot, P.N.1    Solomon, P.R.2    Morris, J.C.3
  • 10
    • 0032926540 scopus 로고    scopus 로고
    • The effects of donepezil in Alzheimer's disease: Results from a multinational trial
    • Burns A, Rossor M, Hecker J, et al. The effects of donepezil in Alzheimer's disease: Results from a multinational trial. Dement Geriatr Cogn Disord 1999; 10: 237-44.
    • (1999) Dement Geriatr Cogn Disord , vol.10 , pp. 237-244
    • Burns, A.1    Rossor, M.2    Hecker, J.3
  • 11
    • 0031883716 scopus 로고    scopus 로고
    • A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease
    • Donepezil Study Group
    • Rogers SL, Farlow MR, Doody RS, Mohs R, Friedhoff LT. A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease. Donepezil Study Group. Neurology 1998; 50: 136-45.
    • (1998) Neurology , vol.50 , pp. 136-145
    • Rogers, S.L.1    Farlow, M.R.2    Doody, R.S.3    Mohs, R.4    Friedhoff, L.T.5
  • 12
    • 0027178189 scopus 로고
    • Functional decline in Alzheimer's disease. A longitudinal study
    • Green C, Mohs RC, Schmeidler J. Functional decline in Alzheimer's disease. A longitudinal study. J Am Geriatr Soc 1993; 41: 654-61.
    • (1993) J Am Geriatr Soc , vol.41 , pp. 654-661
    • Green, C.1    Mohs, R.C.2    Schmeidler, J.3
  • 13
    • 0027441436 scopus 로고
    • Functional status, education and the diagnosis of dementia in the Shanghai survey
    • Hill LR, Klauber MR, Salmon DP. Functional status, education and the diagnosis of dementia in the Shanghai survey. Neurology 1993; 43: 138-45.
    • (1993) Neurology , vol.43 , pp. 138-145
    • Hill, L.R.1    Klauber, M.R.2    Salmon, D.P.3
  • 14
    • 0026595362 scopus 로고
    • Instrumental activities of daily living as a screening tool for cognitive impairment and dementia in elderly community dwellers
    • Barberger-Gateau P, Commenges D, Gagnon M. Instrumental activities of daily living as a screening tool for cognitive impairment and dementia in elderly community dwellers. J Am Geriatr Soc 1992; 40: 1129-34.
    • (1992) J Am Geriatr Soc , vol.40 , pp. 1129-1134
    • Barberger-Gateau, P.1    Commenges, D.2    Gagnon, M.3
  • 15
    • 0029815299 scopus 로고    scopus 로고
    • The evolution of psychiatric symptoms in Alzheimer's disease: A natural history study
    • Jost BC, Grossberg GT. The evolution of psychiatric symptoms in Alzheimer's disease: A natural history study. J Am Geriatr Soc 1996; 44: 1078-81.
    • (1996) J Am Geriatr Soc , vol.44 , pp. 1078-1081
    • Jost, B.C.1    Grossberg, G.T.2
  • 16
    • 0029887389 scopus 로고    scopus 로고
    • The spectrum of behavioral changes in Alzheimer's disease
    • Mega MS, Cummings JL, Fiorello T, Gornbein J. The spectrum of behavioral changes in Alzheimer's disease. Neurology 1996; 46: 130-5.
    • (1996) Neurology , vol.46 , pp. 130-135
    • Mega, M.S.1    Cummings, J.L.2    Fiorello, T.3    Gornbein, J.4
  • 17
    • 0033669090 scopus 로고    scopus 로고
    • Increased neocortical neurofibrillary tangle density in subjects with Alzheimer disease and psychosis
    • Farber NB, Rubin EH, Newcomer JW, Por favor, completar hasta un máximo de 6 autores, et al. Increased neocortical neurofibrillary tangle density in subjects with Alzheimer disease and psychosis. Arch Gen Psychiatry 2000; 57: 1165-73.
    • (2000) Arch Gen Psychiatry , vol.57 , pp. 1165-1173
    • Farber, N.B.1    Rubin, E.H.2    Newcomer, J.W.3
  • 18
    • 0029858216 scopus 로고    scopus 로고
    • Longitudinal assessment of symptoms of depression, agitation, and psychosis in 181 patients with Alzheimer's disease
    • Levy ML, Cummings JL, Fairbanks LA, et al. Longitudinal assessment of symptoms of depression, agitation, and psychosis in 181 patients with Alzheimer's disease. Am J Psychiatry 1996; 153: 1438-43.
    • (1996) Am J Psychiatry , vol.153 , pp. 1438-1443
    • Levy, M.L.1    Cummings, J.L.2    Fairbanks, L.A.3
  • 19
    • 0025861614 scopus 로고
    • Alzheimer's disease. Recognizing and treating a frustrating condition
    • Skelton WP, Skelton NK. Alzheimer's disease. Recognizing and treating a frustrating condition. Postgrad Med 1991; 90: 33-4, 37-41.
    • (1991) Postgrad Med , vol.90 , pp. 33-34
    • Skelton, W.P.1    Skelton, N.K.2
  • 20
    • 0002037940 scopus 로고
    • Cholinergic systems and related neuropathological predilection patterns in Alzheimer disease
    • Bick KL, Katzman R, Terry RD, eds. New York: Raven Press
    • Geula C, Mesulam MM. Cholinergic systems and related neuropathological predilection patterns in Alzheimer disease. In Bick KL, Katzman R, Terry RD, eds. Alzheimer's Disease. New York: Raven Press; 1994. p. 263-91.
    • (1994) Alzheimer's Disease , pp. 263-291
    • Geula, C.1    Mesulam, M.M.2
  • 21
    • 0019410162 scopus 로고
    • Alzheimer disease: Evidence for selective loss of cholinergic neurons in the nucleus basalis
    • Whitehouse PJ, Price DL, Clark AW, Coyle JT, DeLong MR. Alzheimer disease: Evidence for selective loss of cholinergic neurons in the nucleus basalis. Ann Neurol 1981; 10: 122-6.
    • (1981) Ann Neurol , vol.10 , pp. 122-126
    • Whitehouse, P.J.1    Price, D.L.2    Clark, A.W.3    Coyle, J.T.4    DeLong, M.R.5
  • 22
    • 0035091670 scopus 로고    scopus 로고
    • Orbitofrontal and anterior cingulate cortex neurofibrillary tangle burden is associated with agitation in Alzheimer disease
    • Tekin S, Mega MS, Masterman DM, et al. Orbitofrontal and anterior cingulate cortex neurofibrillary tangle burden is associated with agitation in Alzheimer disease. Ann Neurol 2001; 49: 355-61.
    • (2001) Ann Neurol , vol.49 , pp. 355-361
    • Tekin, S.1    Mega, M.S.2    Masterman, D.M.3
  • 23
    • 0034016372 scopus 로고    scopus 로고
    • Mental and behavioral disturbances in dementia: Findings from the cache county study on memory in aging
    • Lyketsos CG, Steinberg M, Tschanz JT, et al. Mental and behavioral disturbances in dementia: Findings from the cache county study on memory in aging. Am J Psychiatry 2000; 157: 708-14.
    • (2000) Am J Psychiatry , vol.157 , pp. 708-714
    • Lyketsos, C.G.1    Steinberg, M.2    Tschanz, J.T.3
  • 24
    • 0141799784 scopus 로고    scopus 로고
    • Effects of two-year treatment with cholinesterase inhibitor rivastigmine on behavioural symptoms in Alzheimer's disease
    • Rösler M, Retz W, Retz-Junginger P, Dennler HJ. Effects of two-year treatment with cholinesterase inhibitor rivastigmine on behavioural symptoms in Alzheimer's disease. Behav Neurol 2000; 11: 211-6.
    • (2000) Behav Neurol , vol.11 , pp. 211-216
    • Rösler, M.1    Retz, W.2    Retz-Junginger, P.3    Dennler, H.J.4
  • 25
    • 0033983966 scopus 로고    scopus 로고
    • Decreased protein levels of nicotinic receptor subunits in the hippocampus and temporal cortex of patients with Alzheimer's disease
    • Guan ZZ, Zhang X, Ravid R, Nordberg A. Decreased protein levels of nicotinic receptor subunits in the hippocampus and temporal cortex of patients with Alzheimer's disease. J Neurochem 2000; 74: 237-43.
    • (2000) J Neurochem , vol.74 , pp. 237-243
    • Guan, Z.Z.1    Zhang, X.2    Ravid, R.3    Nordberg, A.4
  • 26
    • 0028924664 scopus 로고
    • Differential regulation of molecular subtypes of muscarinic receptors in Alzheimer's disease
    • Flynn DD, Ferrari-DiLeo G, Mash DC, Levey AI. Differential regulation of molecular subtypes of muscarinic receptors in Alzheimer's disease. J Neurochem 1995; 64: 1888-91.
    • (1995) J Neurochem , vol.64 , pp. 1888-1891
    • Flynn, D.D.1    Ferrari-DiLeo, G.2    Mash, D.C.3    Levey, A.I.4
  • 28
    • 0027973241 scopus 로고
    • Butyryleholinesterase reactivity differentiates the amyloid plaques of aging from those of dementia
    • Mesulam M, Geula C. Butyryleholinesterase reactivity differentiates the amyloid plaques of aging from those of dementia. Ann Neurol 1994; 36: 722-7.
    • (1994) Ann Neurol , vol.36 , pp. 722-727
    • Mesulam, M.1    Geula, C.2
  • 29
    • 0027337833 scopus 로고
    • Neurological cholinesterases in the normal brain and in Alzheimer's disease: Relationship to plaques, tangles, and patterns of selective vulnerability
    • Wright CI, Geula C, Mesulam MM. Neurological cholinesterases in the normal brain and in Alzheimer's disease: Relationship to plaques, tangles, and patterns of selective vulnerability. Ann Neurol 1993; 34: 373-84.
    • (1993) Ann Neurol , vol.34 , pp. 373-384
    • Wright, C.I.1    Geula, C.2    Mesulam, M.M.3
  • 30
    • 0001983594 scopus 로고
    • Cholinesterase content of certain regions of the spinal cord as judged by histochemical and cartesian diver techniques
    • Giacobini E, Holmstedt B. Cholinesterase content of certain regions of the spinal cord as judged by histochemical and cartesian diver techniques. Acta Physiol Scand 1958; 42; 12-27.
    • (1958) Acta Physiol Scand , vol.42 , pp. 12-27
    • Giacobini, E.1    Holmstedt, B.2
  • 31
    • 0034535351 scopus 로고    scopus 로고
    • Cholinesterase inhibitors stabilize Alzheimer's disease
    • Giacobini E. Cholinesterase inhibitors stabilize Alzheimer's disease. Ann N Y Acad Sci 2000; 920: 321-7.
    • (2000) Ann N Y Acad Sci , vol.920 , pp. 321-327
    • Giacobini, E.1
  • 32
    • 0030763602 scopus 로고    scopus 로고
    • From molecular structure to Alzheimer therapy
    • Giacobini E. From molecular structure to Alzheimer therapy. Jpn J Pharmacol 1997; 74: 225-41.
    • (1997) Jpn J Pharmacol , vol.74 , pp. 225-241
    • Giacobini, E.1
  • 33
    • 0032513557 scopus 로고    scopus 로고
    • Distribution of butyrylcholinesterase in human amygdala and hippocampal formation
    • Darvesh S, Grantham DL, Hopkins DA. Distribution of butyrylcholinesterase in human amygdala and hippocampal formation. J Comp Neurol 1998; 393: 374-90.
    • (1998) J Comp Neurol , vol.393 , pp. 374-390
    • Darvesh, S.1    Grantham, D.L.2    Hopkins, D.A.3
  • 34
    • 0003229465 scopus 로고    scopus 로고
    • Correlation between cognitive effects and level of acetylcholinesterase inhibition in a trial of rivastigmine in Alzheimer's patients
    • abstract NR: 561
    • Costa JF, Anand R, Cutler NR, et al. Correlation between cognitive effects and level of acetylcholinesterase inhibition in a trial of rivastigmine in Alzheimer's patients. Proc Am Psych Assoc 1999 [abstract NR: 561].
    • (1999) Proc Am Psych Assoc
    • Costa, J.F.1    Anand, R.2    Cutler, N.R.3
  • 35
    • 0000174434 scopus 로고    scopus 로고
    • AChE and BuChE activities in CSF of mild AD patients following 12 months of rivastigmine treatment
    • Nordberg A, Darreh-Shori T, Svenson A, Guan Z. AChE and BuChE activities in CSF of mild AD patients following 12 months of rivastigmine treatment. J Neurol Sci 2001; 187: P0144.
    • (2001) J Neurol Sci , vol.187
    • Nordberg, A.1    Darreh-Shori, T.2    Svenson, A.3    Guan, Z.4
  • 36
    • 0002883415 scopus 로고    scopus 로고
    • Improved cognition and plasma ChE inhibition in AD patients receiving rivastigmine for one year: Differential effects across time
    • Nordberg A, Almkvist O, Darreh-Shori T, Spiegel R. Improved cognition and plasma ChE inhibition in AD patients receiving rivastigmine for one year: Differential effects across time. J Neurol Sci 2001a; 187: P0143.
    • (2001) J Neurol Sci , vol.187
    • Nordberg, A.1    Almkvist, O.2    Darreh-Shori, T.3    Spiegel, R.4
  • 37
    • 0000098105 scopus 로고    scopus 로고
    • Improved cortical glucose metabolism in AD patients treated with rivastigmine for one year
    • Nordberg A, Almkvist O, Nilsson A, Wall A, Langstrom B. Improved cortical glucose metabolism in AD patients treated with rivastigmine for one year. J Neurol Sci 2001b; 187: P0409.
    • (2001) J Neurol Sci , vol.187
    • Nordberg, A.1    Almkvist, O.2    Nilsson, A.3    Wall, A.4    Langstrom, B.5
  • 39
    • 0030441663 scopus 로고    scopus 로고
    • Caregivers and behavioral disturbances: Effects and interventions
    • Brodaty H. Caregivers and behavioral disturbances: Effects and interventions. Intern Psychogeriatrics 1996; 8 (Suppl 3): 455-8.
    • (1996) Intern Psychogeriatrics , vol.8 , Issue.SUPPL. 3 , pp. 455-458
    • Brodaty, H.1
  • 41
    • 0019967975 scopus 로고
    • The Global Deterioration Scale for assessment of primary degenerative dementia
    • Reisberg B, Ferris SH, de León MJ, Crook T. The Global Deterioration Scale for assessment of primary degenerative dementia. Am J Psychiatry 1982; 139: 1136-9.
    • (1982) Am J Psychiatry , vol.139 , pp. 1136-1139
    • Reisberg, B.1    Ferris, S.H.2    De León, M.J.3    Crook, T.4
  • 43
    • 0030000603 scopus 로고    scopus 로고
    • The consortium to establish a registry for Alzheimer's disease (CERAD). Part XIV: Demographic and clinical predictions of survival in patients with Alzheimer's disease
    • Heyman A, Peterson B, Fillenbaum G, et al. The consortium to establish a registry for Alzheimer's disease (CERAD). Part XIV: Demographic and clinical predictions of survival in patients with Alzheimer's disease. Neurology 1996; 46: 656-60.
    • (1996) Neurology , vol.46 , pp. 656-660
    • Heyman, A.1    Peterson, B.2    Fillenbaum, G.3
  • 44
    • 0025108077 scopus 로고
    • Assessment of functional changes in Alzheimer's disease
    • Gauthier L, Gauthier S. Assessment of functional changes in Alzheimer's disease. Neuroepidemiology 1990; 9: 183-8.
    • (1990) Neuroepidemiology , vol.9 , pp. 183-188
    • Gauthier, L.1    Gauthier, S.2
  • 45
  • 46
    • 0031941259 scopus 로고    scopus 로고
    • Assessing the impact of neuropsychiatric symptoms in Alzheimer's disease: The Neuropsychiatric Inventory Caregiver Distress Scale
    • Kaufer DI, Cummings JL, Christine D, et al. Assessing the impact of neuropsychiatric symptoms in Alzheimer's disease: The Neuropsychiatric Inventory Caregiver Distress Scale. J Am Geriatr Soc 1998; 46: 210-15.
    • (1998) J Am Geriatr Soc , vol.46 , pp. 210-215
    • Kaufer, D.I.1    Cummings, J.L.2    Christine, D.3
  • 47
    • 0026230201 scopus 로고
    • Anxiety and depressive disorders in adult children caring for demented parents
    • Dura JR, Stukenberg KW, Kiecolt-Glaser JK. Anxiety and depressive disorders in adult children caring for demented parents. Psychol Aging 1991; 6: 467-73.
    • (1991) Psychol Aging , vol.6 , pp. 467-473
    • Dura, J.R.1    Stukenberg, K.W.2    Kiecolt-Glaser, J.K.3
  • 49
    • 0028567287 scopus 로고
    • Net economic costs of dementia in Canada
    • Ostbye T, Crosse E. Net economic costs of dementia in Canada. Can Med Assoc J 1994; 151: 1457-64.
    • (1994) Can Med Assoc J , vol.151 , pp. 1457-1464
    • Ostbye, T.1    Crosse, E.2
  • 50
    • 0032497237 scopus 로고    scopus 로고
    • Relation between severity of Alzheimer's disease and costs of caring
    • Hux MJ, O'Brien BJ, Iskedjian M, et al. Relation between severity of Alzheimer's disease and costs of caring. CMAJ 1998; 159: 457-65.
    • (1998) CMAJ , vol.159 , pp. 457-465
    • Hux, M.J.1    O'Brien, B.J.2    Iskedjian, M.3
  • 51
    • 0030426769 scopus 로고    scopus 로고
    • Theories behind existing scales for rating behavior in dementia
    • Cummings JL. Theories behind existing scales for rating behavior in dementia. Intern Psychogeriatr 1996; 8: 293-300.
    • (1996) Intern Psychogeriatr , vol.8 , pp. 293-300
    • Cummings, J.L.1
  • 52
    • 0026587340 scopus 로고
    • Incontinence and troublesome behaviors predict institutionalization in dementia
    • O'Donnell BF, Drachman DA, Barnes HJ, et al. Incontinence and troublesome behaviors predict institutionalization in dementia. J Geriatr Psychiatry Neurol 1992; 5: 45-52.
    • (1992) J Geriatr Psychiatry Neurol , vol.5 , pp. 45-52
    • O'Donnell, B.F.1    Drachman, D.A.2    Barnes, H.J.3
  • 53
    • 0025142124 scopus 로고
    • Psychiatric symptoms and nursing home placement of patients with Alzheimer's disease
    • Steele C, Rovner B, Chase GA, Folstein M. Psychiatric symptoms and nursing home placement of patients with Alzheimer's disease. Am J Psychol 1990; 147: 1049-51.
    • (1990) Am J Psychol , vol.147 , pp. 1049-1051
    • Steele, C.1    Rovner, B.2    Chase, G.A.3    Folstein, M.4
  • 55
    • 0003799178 scopus 로고    scopus 로고
    • The European Agency for the Evaluation of Medicinal Products. Committee for Proprietary Medicinal Products (CPMP). September, CPMP/EWP/553/95
    • EMEA. The European Agency for the Evaluation of Medicinal Products. Committee for Proprietary Medicinal Products (CPMP). Note for Guidance on Medicinal Products in the Treatment of Alzheimer's Disease. September 1997, CPMP/EWP/553/95.
    • (1997) Note for Guidance on Medicinal Products in the Treatment of Alzheimer's Disease
  • 56
    • 0028897914 scopus 로고
    • Canadian guidelines for the development of antidementia therapies: A conceptual summary
    • Mohr E, Feldman H, Gauthier S. Canadian guidelines for the development of antidementia therapies: A conceptual summary. Can J Neurol Sci 1995; 22: 62-71.
    • (1995) Can J Neurol Sci , vol.22 , pp. 62-71
    • Mohr, E.1    Feldman, H.2    Gauthier, S.3
  • 57
    • 0028863947 scopus 로고
    • Methodologic issues regarding outcome measures for clinical drug trials of psychiatric complications in dementia
    • Teri LL, Logsdon RG. Methodologic issues regarding outcome measures for clinical drug trials of psychiatric complications in dementia. J Geriatr Psych Neurol 1995; 8: S8-S17.
    • (1995) J Geriatr Psych Neurol , vol.8
    • Teri, L.L.1    Logsdon, R.G.2
  • 58
    • 0027429837 scopus 로고
    • Brain selective inhibition of acetylcholinesterase: A novel approach to therapy for Alzheimer's disease
    • Cuello AC, ed. Elsevier Science Publishers
    • Enz A, Amstutz R, Boddeke H, et al. Brain selective inhibition of acetylcholinesterase: a novel approach to therapy for Alzheimer's disease. In Cuello AC, ed. Prog Brain Res 98. Elsevier Science Publishers; 1993. p. 431-8.
    • (1993) Prog Brain Res 98 , pp. 431-438
    • Enz, A.1    Amstutz, R.2    Boddeke, H.3
  • 59
    • 0031902795 scopus 로고    scopus 로고
    • A randomized trail evaluating the efficacy and safety of ENA 713 (rivastigmine tartrate), a new acetylchol/nesterase inhibitor, in patients with mild to moderately severe Alzheimer's disease
    • Corey-Bloom JF, Anand R, Veach J. A randomized trail evaluating the efficacy and safety of ENA 713 (rivastigmine tartrate), a new acetylchol/nesterase inhibitor, in patients with mild to moderately severe Alzheimer's disease. Int J Geriatr Psychopharmacol 1998; 1: 55-65.
    • (1998) Int J Geriatr Psychopharmacol , vol.1 , pp. 55-65
    • Corey-Bloom, J.F.1    Anand, R.2    Veach, J.3
  • 60
    • 0033528436 scopus 로고    scopus 로고
    • Efficacy and safety of rivastigmine in patients with Alzheimer's disease: International randomised controlled trial
    • Rösler M, Anand R, Cicin-Sian A, et al. Efficacy and safety of rivastigmine in patients with Alzheimer's disease: International randomised controlled trial. Br Med J 1999; 318: 633-40.
    • (1999) Br Med J , vol.318 , pp. 633-640
    • Rösler, M.1    Anand, R.2    Cicin-Sian, A.3
  • 61
    • 0011923024 scopus 로고    scopus 로고
    • Impact of Alzheimer's disease and rivastigmine treatment on activities of daily living over the course of mild to moderately severe disease
    • In press
    • Potkin SG, Anand R, Hartman R, Veach J, Grossberg G. Impact of Alzheimer's disease and rivastigmine treatment on activities of daily living over the course of mild to moderately severe disease. Int J Neuropsychopharmacol. [In press].
    • Int J Neuropsychopharmacol
    • Potkin, S.G.1    Anand, R.2    Hartman, R.3    Veach, J.4    Grossberg, G.5
  • 62
    • 0001343442 scopus 로고    scopus 로고
    • Rivastigmine provides behavioral benefits to Alzheimer's disease patients residing in a nursing home: Findings from a 26-week trial
    • Cummings J, Anand R, Koumaras B, Hartman R. Rivastigmine provides behavioral benefits to Alzheimer's disease patients residing in a nursing home: Findings from a 26-week trial [abstract]. Neurology 2000; 54: A468.
    • (2000) Neurology , vol.54
    • Cummings, J.1    Anand, R.2    Koumaras, B.3    Hartman, R.4
  • 65
    • 0011927443 scopus 로고    scopus 로고
    • Treatment with rivastigmine reduces the need for psychotropic medications in patients with Alzheimer's disease residing in long-term care facilities. Poster presented.y Crete, 9-11 March
    • Messina J, Koumaras B, Hartman R. Treatment with rivastigmine reduces the need for psychotropic medications in patients with Alzheimer's disease residing in long-term care facilities. Poster presented at Crete 2000 'Maximising the ABC of Dementia'. Crete, 9-11 March 2000.
    • (2000) Crete 2000 'Maximising the ABC of Dementia'
    • Messina, J.1    Koumaras, B.2    Hartman, R.3
  • 66
    • 0034676757 scopus 로고    scopus 로고
    • Efficacy of rivastigmine in dementia with Lewy bodies: A randomised double-blind, placebo-controlled international study
    • McKeith I, del Ser T, Spano PF, et al. Efficacy of rivastigmine in dementia with Lewy bodies: A randomised double-blind, placebo-controlled international study. Lancet 2000; 356: 2031-6.
    • (2000) Lancet , vol.356 , pp. 2031-2036
    • McKeith, I.1    Del Ser, T.2    Spano, P.F.3
  • 67
    • 0011979626 scopus 로고    scopus 로고
    • A randomised, open-label study on the safety and tolerability of the co-administration of Exelon (rivastigmine) with Risperidal (risperidone) in dementia patients with behavioural disturbances. Poster presented. Crete, 9-11 March
    • Weiser M, Davidson M, Hartman R, et al. A randomised, open-label study on the safety and tolerability of the co-administration of Exelon (rivastigmine) with Risperidal (risperidone) in dementia patients with behavioural disturbances. Poster presented at Crete 2000 'Maximising the ABC of Dementia'. Crete, 9-11 March 2000.
    • (2000) Crete 2000 'Maximising the ABC of Dementia'
    • Weiser, M.1    Davidson, M.2    Hartman, R.3
  • 68
    • 0031784275 scopus 로고    scopus 로고
    • Combination of risperidone and donepezil in Lewy body dementia
    • Geizer M, Ancill RJ. Combination of risperidone and donepezil in Lewy body dementia. Can J Psychiatr 1998; 43: 421-2.
    • (1998) Can J Psychiatr , vol.43 , pp. 421-422
    • Geizer, M.1    Ancill, R.J.2
  • 69
    • 0028270519 scopus 로고
    • A 30-week randomized controlled trial of high-dose tacrine in patients with Alzheimer's disease
    • The Tacrine Study Group
    • Knapp MJ, Knopman DS, Solomon PR, et al. A 30-week randomized controlled trial of high-dose tacrine in patients with Alzheimer's disease. The Tacrine Study Group. JAMA 1994; 271: 985-91.
    • (1994) JAMA , vol.271 , pp. 985-991
    • Knapp, M.J.1    Knopman, D.S.2    Solomon, P.R.3
  • 70
    • 0011923332 scopus 로고    scopus 로고
    • Cognitive effect of rivastigmine, a new generation cholinesterase inhibitor in moderately severe to advanced Alzheimer's disease. Poster presented. Miami, Florida, USA
    • Doraiswamy M, Anand R, Hartman R, et al. Cognitive effect of rivastigmine, a new generation cholinesterase inhibitor in moderately severe to advanced Alzheimer's disease. Poster presented at 13th AAGP 2000. Miami, Florida, USA.
    • (2000) 13th AAGP 2000
    • Doraiswamy, M.1    Anand, R.2    Hartman, R.3
  • 71
    • 0033679259 scopus 로고    scopus 로고
    • A 52-week study of the efficacy of rivastigmine in patients with mild to moderately severe Alzheimer's disease
    • Farlow M, Anand R, Messina J, Hartman R, Veach J. A 52-week study of the efficacy of rivastigmine in patients with mild to moderately severe Alzheimer's disease. Eur J Neurol 2000; 44: 236-41.
    • (2000) Eur J Neurol , vol.44 , pp. 236-241
    • Farlow, M.1    Anand, R.2    Messina, J.3    Hartman, R.4    Veach, J.5
  • 72
    • 0024273881 scopus 로고
    • Clinical predictors of course for Alzheimer patients in a longitudinal study: A preliminary report
    • Kramer-Ginsberg E, Mohs RC, Aryan M, et al. Clinical predictors of course for Alzheimer patients in a longitudinal study: A preliminary report. Psychopharmacol Bull 1988; 24: 458-62.
    • (1988) Psychopharmacol Bull , vol.24 , pp. 458-462
    • Kramer-Ginsberg, E.1    Mohs, R.C.2    Aryan, M.3
  • 75
    • 0034113018 scopus 로고    scopus 로고
    • Lack of drug-drug interactions with rivastigmine for AD
    • Grossberg G, et al. Lack of drug-drug interactions with rivastigmine for AD. Int J Geriatr Psychiatry 2000; 15: 242-7.
    • (2000) Int J Geriatr Psychiatry , vol.15 , pp. 242-247
    • Grossberg, G.1
  • 76
    • 0029778789 scopus 로고    scopus 로고
    • Clinical development of Exelon™ (ENA-713): The ADENA programme
    • Anand R, Gharabawi G. Clinical development of Exelon™ (ENA-713): The ADENA programme. J Drug Dev Clin Pract 1996; 8: 9-14.
    • (1996) J Drug Dev Clin Pract , vol.8 , pp. 9-14
    • Anand, R.1    Gharabawi, G.2
  • 77
    • 0031718551 scopus 로고    scopus 로고
    • Clinical pharmacology of rivastigmine: A new-generation acetylcholinesterase inhibitor for the treatment of Alzheimer's disease
    • Polinsky R. Clinical pharmacology of rivastigmine: A new-generation acetylcholinesterase inhibitor for the treatment of Alzheimer's disease. Clin Ther 1998; 20: 634-47.
    • (1998) Clin Ther , vol.20 , pp. 634-647
    • Polinsky, R.1
  • 78
    • 0034046848 scopus 로고    scopus 로고
    • Dose-response effect of rivastigmine in the treatment of Alzheimer's disease
    • Anand R, Messina J, Hartman R. Dose-response effect of rivastigmine in the treatment of Alzheimer's disease. Int J Geriatr Psychopharmacol 2000b; 2: 68-72.
    • (2000) Int J Geriatr Psychopharmacol , vol.2 , pp. 68-72
    • Anand, R.1    Messina, J.2    Hartman, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.