Inhibitory mechanism of vascular endothelial growth factor (VEGF) by bucillamine

British Journal of Pharmacology

Volumn 137, Issue 6, 2002, Pages 901-909

  Koyama, Shinji ^a   Takagi, Hitoshi ^a   Otani, Atsushi ^a   Oh, Hideyasu ^a   Nishimura, Kazuo ^b   Honda, Yoshihito ^a  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b SANTEN PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Angiogenesis; Bucillamine; Retinal ischaemia; Vascular endothelial growth factor

Indexed keywords

ACETYLCYSTEINE; BUCILLAMINE; PENICILLAMINE; THIOL DERIVATIVE; TRANSCRIPTION FACTOR SP1; VASCULOTROPIN;

ANIMAL CELL; ARTICLE; DIABETIC RETINOPATHY; DRUG EFFECT; DRUG HALF LIFE; DRUG MECHANISM; HYPOXIA; HYPOXIA RESPONSIVE ELEMENT; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN SYNTHESIS; REPORTER GENE; RETINA ISCHEMIA; SERUM RESPONSIVE ELEMENT; TRANSCRIPTION REGULATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CATTLE; CELL HYPOXIA; CELL LINE; CELLS, CULTURED; CYSTEINE; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL GROWTH FACTORS; ENDOTHELIUM, VASCULAR; GENE EXPRESSION REGULATION; HYPOXIA-INDUCIBLE FACTOR 1; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LUCIFERASES; LYMPHOKINES; NUCLEAR PROTEINS; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; RNA STABILITY; RNA, MESSENGER; SP1 TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTOR AP-2; TRANSCRIPTION FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0036856420     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704929     Document Type: Article

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