Differential induction of midazolam metabolism in the small intestine and liver by oral and intravenous dexamethasone pretreatment in rat

Xenobiotica

Volumn 32, Issue 11, 2002, Pages 975-984

  Eeckhoudt, S L ^a   Horsmans, Y ^a   Verbeeck, R K ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYMIDAZOLAM; ALPHA HYDROXYMIDAZOLAM; CYTOCHROME P450 3A1; CYTOCHROME P450 3A2; CYTOCHROME P450 3A4; DEXAMETHASONE; DRUG METABOLITE; MIDAZOLAM; UNCLASSIFIED DRUG; ANTIINFLAMMATORY AGENT; BENZODIAZEPINE RECEPTOR AFFECTING AGENT; CYP3A1 PROTEIN, RAT; CYP3A2 PROTEIN, RAT; MEMBRANE PROTEIN; UNSPECIFIC MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME INDUCTION; GEL ELECTROPHORESIS; IMMUNOBLOTTING; IMMUNOREACTIVITY; LIVER MICROSOME; MALE; NONHUMAN; RAT; SMALL INTESTINE; ANIMAL; BIOSYNTHESIS; DOSE RESPONSE; DRUG EFFECT; ENZYMOLOGY; INTESTINE; INTRAVENOUS DRUG ADMINISTRATION; KINETICS; LIVER; ORAL DRUG ADMINISTRATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; WISTAR RAT;

ANIMALIA; RATTUS NORVEGICUS;

ADMINISTRATION, ORAL; ANIMALS; ANTI-INFLAMMATORY AGENTS; ARYL HYDROCARBON HYDROXYLASES; DEXAMETHASONE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GABA MODULATORS; IMMUNOBLOTTING; INFUSIONS, INTRAVENOUS; INTESTINE, SMALL; INTESTINES; KINETICS; LIVER; MALE; MEMBRANE PROTEINS; MICROSOMES, LIVER; MIDAZOLAM; RATS; RATS, WISTAR;

EID: 0036850880     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.1080/0049825021000012655     Document Type: Article

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