Differential effects of dietary flaxseed protein and soy protein on plasma triglyceride and uric acid levels in animal models

Journal of Nutritional Biochemistry

Volumn 13, Issue 11, 2002, Pages 684-689

  Bhathena, Sam J ^a   Ali, Ali A ^b   Mohamed, Ali I ^c   Hansen, Carl T ^d   Velasquez, Manuel T ^e  

^a BELTSVILLE HUMAN NUTRITION RESEARCH CENTER   (United States)

^b AIN SHAMS UNIVERSITY   (Egypt)

^c VIRGINIA STATE UNIVERSITY   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

^e GEORGE WASHINGTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Cholesterol; Flaxseed; Hypertriglyceridemia; Hyperuricemia; Plasma lipids; Soy protein

Indexed keywords

CHOLESTEROL; CREATININE; LINSEED OIL; NITROGEN; PROTEIN; SOYBEAN PROTEIN; TRIACYLGLYCEROL; UREA; URIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOVASCULAR DISEASE; CHOLESTEROL BLOOD LEVEL; COMPARATIVE STUDY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIETARY INTAKE; MALE; METABOLIC PARAMETERS; NONHUMAN; OBESITY; PROTEIN BLOOD LEVEL; PROTEIN DIET; RAT; RAT STRAIN; RISK FACTOR; TRIACYLGLYCEROL BLOOD LEVEL; UREA NITROGEN BLOOD LEVEL; URIC ACID BLOOD LEVEL;

ANIMALIA; GLYCINE MAX;

EID: 0036848454     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0955-2863(02)00227-9     Document Type: Article

References (44)

1. FDA, Food labeling health claims soy protein and coronary heart disease. Food and Drug Administration. Final rule . Fed Regist. 64:1999;57700-57733.
2. Carroll K.K. Review of clinical studies on cholesterol-lowering response to soy protein. J Am Diet Assoc. 91:1991;820-827.
3. Anderson J.W., Johnstone B.M., Cook-Newell M.E. Meta-analysis of effects of soy protein intake on serum lipids in humans. N Engl J Med. 333:1995;276-282.
4. Sugano M., Yamada Y., Yoshida K., Hashimoto Y., Matsuo T., Kimoto M. The hypocholesterolemic action of the undigested fraction of soy bean protein in rats. Atherosclerosis. 72:1988;115-122.
5. Anthony M.S., Clarkson T.B., Weddle D.L., Wolfe M.S. Effects of soy protein phytoestrogens on cardiovascular risk factors in rhesus monkeys. J Nutr. 125:(suppl):1995;803S-804S.
6. Gatchalian-Yee M., Arimura Y., Ochiai E., Yamada K., Sugano M. Soybean protein lowers serum cholesterol levels in hamsters effect of debittered undigested fraction . Nutrition. 13:1997;633-639.
7. Morita T., Oh-hashi A., Takei K., lkai M., Kasaoka S., Kiriyama S. Cholesterol-lowering effects of soybean, potato and rice proteins depend on their low methionine contents in rats fed a cholesterol-free purified diet. J Nutr. 127:1997;470-477.
8. Wagner J.D., Cefalu W.T., Anthony M.S., Litwak K.N., Zhang L., Clarkson T.B. Dietary soy protein and estrogen replacement improve cardiovascular risk factors and decrease aortic cholesteryl ester content in ovariectomized cynomolgous monkeys. Metabolism. 46:1997;698-705.
9. Potter S.M., Baum J.A., Teng H., Stillman R.J., Shay N.F., Erdman J.W. Jr. Soy protein and isoflavones their effects on blood lipids and bone density in postmenopausal women . Am J Clin Nutr. 68:1998;1375S-1379S.
10. Crouse J.R. III, Morgan T., Terry J.G., Ellis J., Vitolins M., Burke G.L. A randomized trial comparing the effect of casein with that of soy protein containing varying amounts of isoflavones on plasma concentrations of lipids and lipoproteins. Arch Intern Med. 159:1999;2070-2076.
11. Washburn S., Burke G.L., Morgan T., Anthony M. Effect of soy protein supplementation on serum lipoproteins, blood pressure, and menopausal symptoms in perimenopausal women. Menopause. 6:1999;7-13.
12. Teixeira S.R., Potter S.M., Weigel R., Hannum S., Erdman J.W. Jr, Hasler C.M. Effects of feeding 4 levels of soy protein for 3 and 6 wk on blood lipids and apolipoproteins in moderately hypercholesterolemic men. Am J Clin Nutr. 71:2000;1077-1084.
13. Vuorinen-Markkola H., Yki-Jarvinen H. Hyperuricemia and insulin resistance. J Clin Endocrinol Metab. 78:1994;25-29.
14. Schmidt M.I., Watson R.L., Duncan B.B., Metcalf P., Brancati F.L., Sharrett A.R., Davis C.E., Heiss G. Clustering of dyslipidemia, hyperuricemia, diabetes, and hypertension and its association with fasting insulin and central and overall obesity in a general population, Atherosclerosis Risk in Community Study Investigators. Metabolism. 45:1996;699-706.
15. Bonora E., Targher G., Zenere M.B., Saggiani F., Caciatori V., Tosi F., Travia D., Zenti M.G., Branzi P., Muggeo M. Relationship of uric acid concentration to cardiovascular risk factors in young men. Role of obesity and central fat distribution. The Verona Young Men Atherosclerosis Risk Factors Study. Int J Obes Relat Metab Disord. 20:1996;975-980.
16. Rathman W., Funkhouser E., Dyer A.R., Roseman J.M. Relations of hyperuricemia with various components of the insulin resistance syndrome in young black and white adults the CARDIA study. Coronary artery risk development in young adults . Ann Epidemiol. 8:1998;250-261.
17. Castelli W.P. Epidemiology of triglycerides a view from Framingham . Am J Cardiol. 70:1993;3H-9H.
18. Gotto A.M. Triglyceride as a risk factor for coronary artery disease. Am J Cardiol. 82:(9a):1998;22Q-25Q.
19. Cunnane S.C., Ganguli S., Menard C., Liede A.C., Hamadeh M.J., Chen Z.Y., Wolever T.M., Jenkins D.J. High alpha-linolenic acid flaxseed (Linum usitatissimum) some nutritional properties in humans . Br J Nutr. 69:1993;443-453.
20. Bierenbaum M.L., Reichstein R., Watkins T.R. Reducing atherogenic risk in hyperlipemic humans with flaxseed supplementation a preliminary report . J Am Coll Nutr. 12:1993;501-504.
21. Prasad K. Dietary flaxseed in prevention of hypercholesterolemic atherosclerosis. Atherosclerosis. 132:1997;69-76.
22. Jenkins D.J., Kendall C.W., Vidgen E., Agarwal S., Rao A.V., Rosenberg R.S., Diamandis E.P., Novokmet R., Mehling C.C., Perera T., Griffin L.C., Cunnane S.C. Health aspects of partially defatted flaxseed, including effects on serum lipids, oxidative measures, and ex vivo androgen and progestin activity a controlled crossover trial . Am J Clin Nutr. 69:1999;395-402.
23. Friedman M., Brandon D.L., Bates A.H., Hymowitz T. Comparison of a commercial soybean cultivar and an isoline lacking the Kunitz trypsin inhibitor composition, nutritional value, and effects of heating . J Agric Food Chem. 39:1991;327-335.
24. Oomah B.D., Mazza G. Flaxseed proteins - a review. Food Chem. 48:1993;109-114.
25. Bhatty R.S. Nutrient composition of whole flaxseed and flaxseed meal. Cunnane S.C., Thompson L.U., Flaxseed in Human Nutrition. 1995;22-42 AOCS Press, Champaign, IL.
26. Shimokawa I., Higami Y., Hubbard G.B., McMahan C.A., Masoro E.J., Yu B.P. Diet and the suitability of the male Fisher 344 rat as a model for aging research. J Gerontol. 48:1993;B27-B32.
27. Turturro A., Witt W.W., Lewis S., Hass B.S., Lipman R.D., Hart R.W. Growth curves and survival characteristics of the animals used in the biomarkers of the aging program. J Gerontol Biol Sci Med Sci. 54:1999;B492-B501.
28. Michaelis O.E. IV, Ellwood K.C., Judge J.M., Schoene N.W., Hansen C.T. Effect of dietary sucrose on the SHR/N-corpulent rat a new model for insulin-independent diabetes . Am J Clin Nutr. 39:1984;612-618.
29. Michaelis O.E. IV, Patrick D.H., Hansen C.T., Canary J.J., Werner R.M., Carswell N. Spontaneous hypertensive/NIH-corpulent rat. Animal model for insulin-independent diabetes mellitus (Type II). Am J Pathol. 123:1986;398-400.
30. Voyles N.R., Powell A.M., Timmers K.I., Wilkins S.D., Bhathena S.J., Hansen C., Michaelis O.E. IV, Recant L. Reversible impairment of glucose-induced insulin secretion in SHR/N-cp rats. Genetic model of type II diabetes. Diabetes. 37:1988;398-404.
31. Michaelis O.E. IV, Carswell N., Velasquez M.T., Hansen C.T. The role of obesity, hypertension, and diet in diabetes and its complication in the spontaneous hypertensive/NIH-corpulent rat. Nutrition. 5:1989;56-59.
32. Reeves P.G., Nielsen F.H., Fahey G.C. Jr. AIN-93 purified diets for laboratory rodents final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diets . J Nutr. 123:1993;1939-1951.
33. Radcliffe J.D., Czajka-Narins D.M. Partial replacement of dietary casein with soy protein isolate can reduce the severity of retinoid-induced hypertriglyceridemia. Plant Foods Hum Nutr. 52:1998;97-108.
34. Babu U.S., Mitchell G.V., Wiesenfeld P., Jenkins M.Y., Gowda H. Nutritional and hematological impact of dietary flaxseed and defatted flaxseed meal in rats. Int J Food Sci Nutr. 51:2000;109-117.
35. Singer P., Jaeger W., Berger I., Barleben H., Wirth M., Richter-Heinrich E., Voigt S., Godicke W. Effects of dietary oleic, linoleic and a-linolenic acids on blood pressure, serum lipids, lipoproteins, and the formation of eicosanoid precursors in patients with mild essential hypertension. J Hum Hyperten. 4:1990;227-233.
36. Cunnane S.C., Chen Z.-Y., Yang J., Liede A.C., Hamadeh M., Crawford M.A. a-linolenic acid in humans Direct functional role or dietary precursor? Nutrition. 7:1991;437-439.
37. Chan J.K., Bruce V.M., McDonald B.E. Dietary a-linolenic acid is as effective as oleic acid and linoleic acid in lowering blood cholesterol in normolipidemic men. Am J Clin Nutr. 53:1991;1230-1234.
38. Prasad K., Mantha S.V., Muir A.D., Westcott N.D. Reduction of hypercholesterolemic atherosclerosis by CDC-flaxseed with very low alpha linolenic acid. Atherosclerosis. 136:1998;367-375.
39. Garrel D.R., Verdy M., PetitClerc C., Martin C., Brule D., Hamet P. Milk- and soy-protein ingestion acute effect on serum uric acid concentration . Am J Clin Nutr. 53:1991;665-669.
40. Setchell K.D.R. Phytoestrogens, The biochemistry, physiology, and implications for human health of soy phytoestrogens. Am J Clin Nutr. 68:(suppl):1998;1333S-1348S.
41. Anthony M.S., Clarkson T.B., Williams J.K. Effects of soy isoflavones on atherosclerosis potential mechanisms . Am J Clin Nutr. 68:(suppl):1998;1390S-1393S.
42. Thompson L.U., Robb P., Serraino M., Cheung F. Mammalian lignan production from various foods. Nutr. Cancer. 16:1991;43-52.
43. Kitts D.D., Yuan Y.V., Wijewickreme A.N., Thompson L.U. Antioxidant activity of the flaxseed secoisolariciresinol diglycoside and its mammalian lignan metabolites enterodiol and enterolactone. Mol Cell Biochem. 202:1999;91-100.
44. Prasad K. Reduction of serum cholesterol and hypercholesterolemic atherosclerosis in rabbits by secoisolariciresinol diglucoside from flaxseed. Circulation. 99:1999;1355-1362.