Quantitative analysis of apoptosis-related gene expression in hepatocellular carcinoma

Cancer

Volumn 95, Issue 9, 2002, Pages 1938-1945

  Ikeguchi, Masahide ^a   Hirooka, Yasuaki ^a   Kaibara, Nobuaki ^a  

^a TOTTORI UNIVERSITY   (Japan)

Author keywords

Apoptosis; bax; bcl 2; Disease recurrence; Hepatocellular carcinoma (HCC); Real time reverse transcriptase polymerase chain reaction (RT PCR); Survivin

Indexed keywords

GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; SURVIVIN; TUMOR MARKER;

ADULT; AGED; APOPTOSIS; ARTICLE; CANCER RECURRENCE; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HIGH RISK PATIENT; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER CELL CARCINOMA; MALE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, NEOPLASM; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CELL DIVISION; FEMALE; GENE EXPRESSION; GENES, BCL-2; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; HUMANS; IMMUNOHISTOCHEMISTRY; LIVER; LIVER NEOPLASMS; MALE; MICROTUBULE-ASSOCIATED PROTEINS; MIDDLE AGED; NEOPLASM PROTEINS; NEOPLASM RECURRENCE, LOCAL; PROGNOSIS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR CELLS, CULTURED;

EID: 0036841260     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/cncr.10898     Document Type: Article

References (32)

1. Bain I, McMaster P. Benign and malignant liver tumors. Surgery. 1997;15:169-174.
2. Fong Y, Sun RL, Jarnagin W, Blumgart LH. An analysis of 412 cases of hepatocellular carcinoma at a Western center. Ann Surg. 1999;229:790-800.
3. The Liver Cancer Study Group of Japan. Primary liver cancer in Japan. Clinicopathologic features and results of surgical treatment. Ann Surg. 1990;211:277-287.
4. Mise K, Tashiro S, Yogita S, et al. Assessment of the biological malignancy of hepatocellular carcinoma: Relationship to clinicopathological factors and prognosis. Clin Cancer Res. 1998;4:1475-1482.
5. Tanaka D, Toh Y, Adachi E, Matsumura T, Mori R, Sugimachi K. Tumor progression in hepatocellular carcinoma may be mediated by p53 mutation. Cancer Res. 1993;53:2884-2887.
6. Piao Z, Kim H, Jeon BK, Lee WJ, Park C. Relationship between loss of heterozygosity of tumor suppressor genes and histologic differentiation in hepatocellular carcinoma. Cancer. 1997;80:865-872.
7. Park YN, Chae KJ, Kim YB, Park C, Theise N. Apoptosis and proliferation in hepatocarcinogenesis related to cirrhosis. Cancer. 2001;92:2733-2738.
8. Ito Y, Matsuura N, Sakon M, et al. Both cell proliferation and apoptosis significantly predict shortened disease-free survival in hepatocellular carcinoma. Br J Cancer. 1999;81:747-751.
9. Finucan DM, Bossy-Wetzel E, Waterhouse NJ, Cotter TG, Green DR. Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibited by Bcl-XL. J Biol Chem. 1999;274:2225-2233.
10. Li P, Nijhawan D, Budihardjo I, et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell. 1997;91:479-489.
11. Oltvai Z, Milliman C, Korsmeyer S. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell. 1993;74:609-619.
12. Clem RJ, Miller LK. Control of programmed cell death by the baculovirus genes p53 and iap. Mol Cell Biol. 1994;14:5212-5222.
13. Mahotka C, Wenzel M, Springer E, Gabbert HE, Gerharz CD. Survivin-δEx3 and survivin-2B: Two novel splice variants of the apoptosis inhibitor survivin with different antiapoptotic properties. Cancer Res. 1999;59:6097-6102.
14. Li F, Ambrosini G, Chu EY, et al. Control of apoptosis and mitotic spindle checkpoint by survivin. Nature. 1998;396:580-583
15. Liver Cancer Study Group of Japan. Classification of Primary Liver Cancer [First English Edition]. Tokyo: Kanehara, 1997.
16. Yajima T, Yagihashi A, Kameshima H, et al. Quantitative reverse transcription-PCR assay of the RNA component of human telomerase using the TaqMan fluorogenic detection system. Clin Chem. 1998;44:2441-2445.
17. Mitas M, Mikhitarian K, Walters C, et al. Quantitative real-time RT-PCR detection of breast cancer micrometastasis using a multigene marker panel. Int J Cancer. 2001;93:162-171.
18. Ikeguchi M, Tatebe S, Kaibara N, Ito H. Changes in levels of expression of p53 and the product of the bcl-2 in lines of gastric cancer cells during cisplatin-induced apoptosis. Eur Surg Res. 1997;29:396-402.
19. Ikeguchi M, Sato N, Hirooka Y, Kaibara N. Computerized nuclear morphometry of hepatocellular carcinoma and its relation to proliferative activity. J Surg Oncol. 1998;68:225-230.
20. Datta R, Manome Y, Taneja N, et al. Overexpression of Bcl-XL by cytotoxic drug exposure confers resistance to ionizing radiation-induced internucleosomal DNA fragmentation. Cell Growth Differ. 1995;6:363-370.
21. Pataer A, Fang B, Yu R, et al. Adenoviral Bak overexpression mediates caspase-dependent tumor killing. Cancer Res. 2000;60:788-792.
22. Inada T, Kikuyama S, Ichikawa A, Igarashi S, Ogata Y. Bcl-2 expression as a prognostic factor of survival of gastric carcinoma. Anticancer Res. 1998;18:2003-2010.
23. Joensuu H, Pylkkanen L, Toikkannen S. Bcl-2 protein expression and long-term survival in breast cancer. Am J Pathol. 1994;145:1191-1198.
24. Sarbia M, Bittinger F, Grabellus F, et al. Expression of BAX, a pro-apoptotic member of the bcl-2 family, in esophageal squamous cell carcinoma. Int J Cancer. 1997;73:508-513,
25. Borner MM, Brousset P, Pfanner-Meyer B, et al. Expression of apoptosis regulatory proteins of the Bcl-2 family and p53 in primary resected non-small-cell lung cancer. Br J Cancer. 1999;79:952-958.
26. Adida C, Crotty PL, McGrath J, Berrebi D, Diebold J, Altieri DC. Developmentally regulated expression of the novel cancer anti-apoptosis gene survivin in human and mouse differentiation. Am J Pathol. 1998;152:43-49.
27. Sarela Al, Macadam RCA, Farmery SM, Markham AF, Guillou PJ. Expression of the antiapoptosis gene, Survivin, predicts death from recurrent colorectal carcinoma. Gut. 2000;46:645-650.
28. Monzó M, Rosell R, Felip E, et al. A novel anti-apoptosis gene: Re-expression of survivin messenger RNA as a prognosis marker in non-small cell lung cancers. J Clin Oncol. 1999;17:2100-2104.
29. Ito T, Shiraki K, Sugimoto K, et al. Survivin promotes cell proliferation in human hepatocellular carcinoma. Hepatology. 2000;31:1080-1085.
30. Suzuki R, Takemura K, Tsutsumi M, Nakamura S, Hamajima N, Seto M. Detection of cyclin D1 overexpression by real-time reverse-transcriptase-method quantitative polymerase chain reaction for the diagnosis of mantle cell lymphoma. Am J Pathol. 2001;159:425-429.
31. Freeman WM, Walker SJ, Vrana KE. Quantitative PCR: Pitfalls and potential. Biotechniques. 1999;26:112-122.
32. Wittwer CT, Hermann MG, Moss AA, Rasmussen RP. Continuous fluorescence monitoring of rapid cycle DNA amplification. Biotechniques. 1997;22:130-308.