Pharmacology of Na+/Ca2+ exchanger

Annals of the New York Academy of Sciences

Volumn 976, Issue , 2002, Pages 513-519

  Kimura, Junko ^a   Watanabe, Yasuhide ^a,b   Li, Libing ^a   Watano, Tomokazu ^a  

^a FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

^b HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Amiodarone; Antiarrhythmic agents; KBR7943; Na+ Ca2+ exchanger; NCX pharmacology

Indexed keywords

2 [2 [4 (4 NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA METHANESULFONATE; AMIODARONE; ANTIARRHYTHMIC AGENT; APRINDINE; BEPRIDIL; CIBENZOLINE; DILTIAZEM; DISOPYRAMIDE; FLECAINIDE; LIDOCAINE; PIRMENOL; PROCAINAMIDE; PROPAFENONE; QUINIDINE; SODIUM CALCIUM EXCHANGE PROTEIN; SOTALOL; VERAPAMIL; 2 (2 (4 (4 NITROBENZYLOXY)PHENYL)ETHYL)ISOTHIOUREA METHANESULFONATE; 2-(2-(4-(4-NITROBENZYLOXY)PHENYL)ETHYL)ISOTHIOUREA METHANESULFONATE; CALCIUM; DRUG DERIVATIVE; THIOUREA;

CONCENTRATION RESPONSE; CONFERENCE PAPER; DRUG EFFECT; DRUG STRUCTURE; MOLECULAR MODEL; PHARMACOLOGY; ANIMAL; ARTICLE; BIOLOGICAL MODEL; DRUG ANTAGONISM; PHYSIOLOGY; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; CALCIUM; MODELS, BIOLOGICAL; MODELS, CARDIOVASCULAR; SODIUM-CALCIUM EXCHANGER; STRUCTURE-ACTIVITY RELATIONSHIP; THIOUREA;

EID: 0036833976     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2002.tb04785.x     Document Type: Conference Paper

References (22)

1. NOBLE, D. 1996. Commentary. Ann. N.Y. Acad. Sci. 779: 1-6.
2. 2+ exchange current in guinea-pig cardiac ventricular cells. Br. J. Pharmacol. 119: 555-563.
3. WATANO, T. & J. KIMURA. 1998. Calcium-dependent inhibition of the sodium-calcium exchange current by KB-R7943. Can. J. Cardiol. 14: 259-262.
4. 2+ exchange current by KB-R7943 in guinea-pig cardiac myocytes. Br. J. Pharmacol. 128: 969-974.
5. 2+ exchange current in guinea-pig cardiac ventricular myocytes. Br. J. Pharmacol. 132: 1317-1325.
6. 2+ exchange current in guinea-pig cardiac myocytes. Br. J. Pharmacol. 131: 80-84.
7. 2+ exchange current in guinea-pig cardiac ventricular myocytes. Jpn. J. Pharmacol. 85: 370-375.
8. 2+ exchange current in guinea-pig cardiac ventricular myocytes. Br. J. Pharmacol. 136: 361-366.
9. 2+ exchange current inhibitory drugs in Sicilian Gambit. Jpn. J. Pharmacol. 88: Suppl. 1. 273P.
10. MIURA, Y. & J. KIMURA. 1989. Sodium-calcium exchange current. Dependence on internal Ca and Na and competitive binding of external Na and Ca. J. Gen. Physiol. 93: 1129-1145.
11. LI, L. & J. KIMURA. 2002. Effect of KB-R7943 on oscillatory Na+/Ca2+ exchange current in guinea-pig ventricular myocytes. Ann. N.Y. Acad. Sci. This volume.
12. 2+ exchange by KB-R7943: transport mode selectivity and antiarrhythmic consequences. Am. J. Physiol. 281: H1334-H1345.
13. 2+ exchanger. Mol. Pharmacol. 59: 524-531.
14. TASK FORCE OF THE WORKING GROUP ON ARRHYTHMIAS OF THE EUROPEAN SOCIETY OF CARDIOLOGY. 1991. The Sicilian Gambit. A new approach to the classification of antiarrhythmic drugs based on their actions on arrhythmogenic mechanisms. Circulation 84: 1831-1851.
15. KODAMA, I., K. KAMIYA & J. TOYAMA. 1997. Cellular electropharmacology of amiodarone. Cardiovasc. Res. 35: 13-29.
16. 2+ exchange in giant excised sarcolemmal membrane patches. Nature 344: 242-245.
17. MATUSOKA, S. & D.W. HILGEMANN. 1994. Inactivation of outward Na-Ca exchange current in guinea-pig ventricular myocytes. J. Physiol. 476: 443-458.
18. DOERING, A.E. & W.J. LEDERER. 1993. The mechanism by cytoplasmic protons inhibit the sodium-calcium exchanger in guinea-pig heart cells. J. Physiol. 476: 443-458.
19. 2+ exchanger. J. Biol. Chem. 275: 22961-22968.
20. 2+ exchange current in guinea-pig cardiac ventricular cells. Folia Pharmacol. Jpn. 119: 2P (abstract in Japanese).
21. 2+ exchanger, attenuates reperfusion injury in the in vitro and in vivo cerebral ischemic models. J. Pharm. Exp. Ther. 298: 249-256.
22. 2+ exchange inhibitor, on ischemia-reperfusion-injured hearts. Jpn. J. Pharmacol. 88: Suppl. 1, 257P.