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Volumn 7, Issue 11, 2002, Pages 1135-1147

Functional domains of paired-like homeoprotein Cart1 and the relationship between dimerization and transcription activity

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; HOMEODOMAIN PROTEIN; ISOPROTEIN; PALINDROMIC DNA; CART1 PROTEIN, RAT; DNA BINDING PROTEIN;

EID: 0036829654     PISSN: 13569597     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2443.2002.00587.x     Document Type: Article
Times cited : (22)

References (36)
  • 1
    • 0026530492 scopus 로고
    • Allosteric underwinding of DNA is a critical step in the positive control of transcription by Hg-MerR
    • Ansari, A.Z., Chael, M.L. & O'Halloran, TV (1992) Allosteric underwinding of DNA is a critical step in the positive control of transcription by Hg-MerR. Nature 355, 87-89.
    • (1992) Nature , vol.355 , pp. 87-89
    • Ansari, A.Z.1    Chael, M.L.2    O'Halloran, T.V.3
  • 2
    • 0032544679 scopus 로고    scopus 로고
    • Human CART1, a paired-class homeodomain protein, activates transcription through palindromic binding sites
    • Cai, R.L. (1998) Human CART1, a paired-class homeodomain protein, activates transcription through palindromic binding sites. Biochem. Biophys. Res. Commun. 250, 305-311.
    • (1998) Biochem. Biophys. Res. Commun , vol.250 , pp. 305-311
    • Cai, R.L.1
  • 3
    • 0028587375 scopus 로고
    • Pax-3 contains domains for transcription activation and transcription inhibition
    • Chalepakis, G., Jones, FS., Edelman, G.M. & Gruss, P. (1994) Pax-3 contains domains for transcription activation and transcription inhibition. Proc. Natl. Acad. Sci. USA 91, 12745-12749.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 12745-12749
    • Chalepakis, G.1    Jones, F.S.2    Edelman, G.M.3    Gruss, P.4
  • 4
    • 0000932904 scopus 로고    scopus 로고
    • Critical residues of the homeodomain involved in contacting DNA bases also specify the nuclear accumulation of thyroid transcription factor-1
    • Christophe-Hobertus, C., Duquesne, V., Pichon, B., Roger, P.P. & Christophe, D. (1999) Critical residues of the homeodomain involved in contacting DNA bases also specify the nuclear accumulation of thyroid transcription factor-1. Eur. J. Biochem. 265, 491-497.
    • (1999) Eur. J. Biochem , vol.265 , pp. 491-497
    • Christophe-Hobertus, C.1    Duquesne, V.2    Pichon, B.3    Roger, P.P.4    Christophe, D.5
  • 6
    • 0032561414 scopus 로고    scopus 로고
    • Human Prop-1: Cloning, mapping, genomic structure. Mutations in familial combined pituitary hormone deficiency
    • Duquesnoy, P., Roy, A., Dastot, F., et al. (1998) Human Prop-1: cloning, mapping, genomic structure. Mutations in familial combined pituitary hormone deficiency. FEBS Lett. 437, 216-220.
    • (1998) FEBS Lett , vol.437 , pp. 216-220
    • Duquesnoy, P.1    Roy, A.2    Dastot, F.3
  • 7
    • 0033048708 scopus 로고    scopus 로고
    • Evolution of homeobox genes: Q50 Paired-like genes founded the Paired class
    • Galliot, B., de Vargas, C. & Miller, D. (1999) Evolution of homeobox genes: Q50 Paired-like genes founded the Paired class. Dev. Genes Evol. 209, 186-197.
    • (1999) Dev. Genes Evol , vol.209 , pp. 186-197
    • Galliot, B.1    de Vargas, C.2    Miller, D.3
  • 9
    • 0029839899 scopus 로고    scopus 로고
    • Human Cart-1: Structural organization, chromosomal localization, and functional analysis of a cartilage-specific homeodomain cDNA
    • Gordon, D.F., Wagner, J., Atkinson, B.L., et al. (1996) Human Cart-1: structural organization, chromosomal localization, and functional analysis of a cartilage-specific homeodomain cDNA. DNA Cell Biol. 15, 531-541.
    • (1996) DNA Cell Biol , vol.15 , pp. 531-541
    • Gordon, D.F.1    Wagner, J.2    Atkinson, B.L.3
  • 10
    • 0034696798 scopus 로고    scopus 로고
    • The homeodomain of Nkx2.2 carries two cooperatively acting nuclear localization signals
    • Hessabi, B., Schmidt, I. & Walther, R. (2000) The homeodomain of Nkx2.2 carries two cooperatively acting nuclear localization signals. Biochem. Biophys. Res. Commun, 270, 695-700.
    • (2000) Biochem. Biophys. Res. Commun , vol.270 , pp. 695-700
    • Hessabi, B.1    Schmidt, I.2    Walther, R.3
  • 11
    • 0033854959 scopus 로고    scopus 로고
    • Activation of specific MEK-ERK cascade is necessary for TGFbeta signaling and crosstalk with PKA and PKC pathways in cultured rat articular chondrocytes
    • Hirota, Y, Tsukazaki, T., Yonekura, A., et al. (2000) Activation of specific MEK-ERK cascade is necessary for TGFbeta signaling and crosstalk with PKA and PKC pathways in cultured rat articular chondrocytes. Osteoarthr. Cartilage 8, 241-247.
    • (2000) Osteoarthr. Cartilage , vol.8 , pp. 241-247
    • Hirota, Y.1    Tsukazaki, T.2    Yonekura, A.3
  • 12
    • 0018410773 scopus 로고
    • Transmission of allosteric effects in DNA
    • Hogan, M., Dattagupta, N. & Crothers, D.M. (1979) Transmission of allosteric effects in DNA. Nature 278, 521-524.
    • (1979) Nature , vol.278 , pp. 521-524
    • Hogan, M.1    Dattagupta, N.2    Crothers, D.M.3
  • 13
    • 0033559209 scopus 로고    scopus 로고
    • Dominant-negative Smad2 mutants inhibit activin/Vg1 signaling and disrupt axis formation in Xenopus
    • Hoodless, P.A., Tsukazaki, T., Nishimatsu, S., Attisano, L., Wrana, J.L. & Thomsen, G.H. (1999) Dominant-negative Smad2 mutants inhibit activin/Vg1 signaling and disrupt axis formation in Xenopus. Dev. Biol. 207, 364-379,
    • (1999) Dev. Biol , vol.207 , pp. 364-379
    • Hoodless, P.A.1    Tsukazaki, T.2    Nishimatsu, S.3    Attisano, L.4    Wrana, J.L.5    Thomsen, G.H.6
  • 14
    • 0025116879 scopus 로고
    • Molecular and genetic organization of the antennapedia gene complex of Drosophila melanogaster
    • Kaufman, T.C., Seeger, M.A. & Olsen, G. (1990) Molecular and genetic organization of the antennapedia gene complex of Drosophila melanogaster. Adv. Genet. 27, 309-362.
    • (1990) Adv. Genet , vol.27 , pp. 309-362
    • Kaufman, T.C.1    Seeger, M.A.2    Olsen, G.3
  • 15
    • 0032528041 scopus 로고    scopus 로고
    • Smad proteins exist as monomers in vivo and undergo homo- and hetero-oligomerization upon activation by serine/threonine kinase receptors
    • Kawabata, M., Inoue, H., Hanyu, A., Imamura, T. & Miyazono, K. (1998) Smad proteins exist as monomers in vivo and undergo homo- and hetero-oligomerization upon activation by serine/ threonine kinase receptors. EMBO J. 17, 4056-4065.
    • (1998) EMBO J , vol.17 , pp. 4056-4065
    • Kawabata, M.1    Inoue, H.2    Hanyu, A.3    Imamura, T.4    Miyazono, K.5
  • 16
    • 0025188837 scopus 로고
    • Crystal structure of an engrailed homeodomain-DNA complex at 2.8 ̊A resolution: A framework for understanding homeodomain-DNA interactions
    • Kissinger, C.R., Liu, B.S., Martin-Blanco, E., Kornberg, T.B. & Pabo, C.O. (1990) Crystal structure of an engrailed homeodomain-DNA complex at 2.8 ̊A resolution: a framework for understanding homeodomain-DNA interactions. Cell 63, 579-590.
    • (1990) Cell , vol.63 , pp. 579-590
    • Kissinger, C.R.1    Liu, B.S.2    Martin-Blanco, E.3    Kornberg, T.B.4    Pabo, C.O.5
  • 17
    • 0021139598 scopus 로고
    • Sequence of a Drosophila segmentation gene: Protein structure homology with DNA-binding proteins
    • Laughon, A. & Scott, M.P. (1984) Sequence of a Drosophila segmentation gene: protein structure homology with DNA-binding proteins. Nature 310, 25-31.
    • (1984) Nature , vol.310 , pp. 25-31
    • Laughon, A.1    Scott, M.P.2
  • 18
    • 0024157206 scopus 로고
    • Homeobox proteins as sequence-specific transcription factors
    • Levine, M. & Hoey, T. (1988) Homeobox proteins as sequence-specific transcription factors. Cell 55, 537-540.
    • (1988) Cell , vol.55 , pp. 537-540
    • Levine, M.1    Hoey, T.2
  • 19
    • 0035830836 scopus 로고    scopus 로고
    • Super-activation of Pax6-mediated transactivation from paired domain-binding sites by DNA-independent recruitment of different homeodomain proteins
    • Mikkola, I., Bruun, J.A., Holm, T. & Johansen, T. (2001) Super-activation of Pax6-mediated transactivation from paired domain-binding sites by DNA-independent recruitment of different homeodomain proteins. J. Biol. Chem. 276, 4109-4118.
    • (2001) J. Biol. Chem , vol.276 , pp. 4109-4118
    • Mikkola, I.1    Bruun, J.A.2    Holm, T.3    Johansen, T.4
  • 20
    • 0034703019 scopus 로고    scopus 로고
    • The leucine zipper of NRL interacts with the CRX homeodomain. A possible mechanism of transcriptional synergy in rhodopsin regulation
    • Mitton, K.P., Swain, P.K., Chen, S., Xu, S., Zack, D.J. & Swaroop, A. (2000) The leucine zipper of NRL interacts with the CRX homeodomain. A possible mechanism of transcriptional synergy in rhodopsin regulation. J. Biol. Chem. 275, 29794-29799.
    • (2000) J. Biol. Chem , vol.275 , pp. 29794-29799
    • Mitton, K.P.1    Swain, P.K.2    Chen, S.3    Xu, S.4    Zack, D.J.5    Swaroop, A.6
  • 21
    • 0033830252 scopus 로고    scopus 로고
    • Dexamethasone inhibition of TGF beta-induced cell growth and type II collagen mRNA expression through ERK-integrated AP-1 activity in cultured rat articular chondrocytes
    • Miyazaki, Y., Tsukazaki, T., Hirota, Y., et al. (2000) Dexamethasone inhibition of TGF beta-induced cell growth and type II collagen mRNA expression through ERK-integrated AP-1 activity in cultured rat articular chondrocytes. Osteoarth. Cartilage 8, 378-385.
    • (2000) Osteoarth. Cartilage , vol.8 , pp. 378-385
    • Miyazaki, Y.1    Tsukazaki, T.2    Hirota, Y.3
  • 22
    • 0035955346 scopus 로고    scopus 로고
    • A 30-base-pair element in the first intron of SOX9 acts as an enhancer in ATDC5
    • Morishita, M., Kishino, T., Furukawa, K., et al. (2001) A 30-base-pair element in the first intron of SOX9 acts as an enhancer in ATDC5. Biochem. Biophys. Res. Commun. 288, 347-355.
    • (2001) Biochem. Biophys. Res. Commun , vol.288 , pp. 347-355
    • Morishita, M.1    Kishino, T.2    Furukawa, K.3
  • 23
    • 0024997404 scopus 로고
    • Protein-DNA contacts in the structure of a homeodomain-DNA complex determined by nuclear magnetic resonance spectroscopy in solution
    • Otting, G., Qian, Y.Q., Billeter, M., et al. (1990) Protein-DNA contacts in the structure of a homeodomain-DNA complex determined by nuclear magnetic resonance spectroscopy in solution. EMBO J. 9, 3085-3092.
    • (1990) EMBO J , vol.9 , pp. 3085-3092
    • Otting, G.1    Qian, Y.Q.2    Billeter, M.3
  • 24
    • 0024407460 scopus 로고
    • The structure of the Antennapedia homeodomain determined by NMR spectroscopy in solution: Comparison with prokaryotic repressors
    • Qian, Y.Q, Billeter, M., Otting, G., Muller, M., Gehring, W.J. & Wuthrich, K. (1989) The structure of the Antennapedia homeodomain determined by NMR spectroscopy in solution: comparison with prokaryotic repressors. Cell 59, 573-580.
    • (1989) Cell , vol.59 , pp. 573-580
    • Qian, Y.Q.1    Billeter, M.2    Otting, G.3    Muller, M.4    Gehring, W.J.5    Wuthrich, K.6
  • 25
    • 0030608661 scopus 로고    scopus 로고
    • Alx-4: cDNA cloning and characterization of a novel paired-type homeodomain protein
    • Qu, S., Li, L. & Wisdom, R. (1997a) Alx-4: cDNA cloning and characterization of a novel paired-type homeodomain protein. Gene 203, 217-223.
    • (1997) Gene , vol.203 , pp. 217-223
    • Qu, S.1    Li, L.2    Wisdom, R.3
  • 26
    • 0030782397 scopus 로고    scopus 로고
    • Polydactyly and ectopic ZPA formation in Alx-4 mutant mice
    • Qu, S., Niswender, K.D., Ji, Q., et al. (1997b) Polydactyly and ectopic ZPA formation in Alx-4 mutant mice. Development 124, 3999-4008.
    • (1997) Development , vol.124 , pp. 3999-4008
    • Qu, S.1    Niswender, K.D.2    Ji, Q.3
  • 27
    • 0031875540 scopus 로고    scopus 로고
    • Mutations in mouse Aristaless-like4 cause Strong's luxoid polydactyly
    • Qu, S., Tucker, S.C., Ehrlich, J.S., et al. (1998) Mutations in mouse Aristaless-like4 cause Strong's luxoid polydactyly. Development 125, 2711-2721.
    • (1998) Development , vol.125 , pp. 2711-2721
    • Qu, S.1    Tucker, S.C.2    Ehrlich, J.S.3
  • 28
    • 0032915190 scopus 로고    scopus 로고
    • Physical and genetic interactions between Alx4 and Cart1
    • Qu. S., Tucker, S.C., Zhao, Q., deCrombrugghe, B. & Wisdom, R. (1999) Physical and genetic interactions between Alx4 and Cart1. Development 126, 359-369.
    • (1999) Development , vol.126 , pp. 359-369
    • Qu, S.1    Tucker, S.C.2    Zhao, Q.3    deCrombrugghe, B.4    Wisdom, R.5
  • 30
    • 0000744672 scopus 로고    scopus 로고
    • Dissection of the transactivation function of the transcription factor encoded by the eye developmental gene PAX6
    • Tang, H.K., Singh, S. & Saunders, G.F (1998) Dissection of the transactivation function of the transcription factor encoded by the eye developmental gene PAX6. J. Biol. Chem. 273, 7210-7221.
    • (1998) J. Biol. Chem , vol.273 , pp. 7210-7221
    • Tang, H.K.1    Singh, S.2    Saunders, G.F.3
  • 31
    • 0032428684 scopus 로고    scopus 로고
    • SARA, a FYVE domain protein that recruits Smad2 to the TGFβ receptor
    • Tsukazaki, T., Chiang, T.A., Davison, A.E, Attisano, L. & Wrana,J.L. (1998) SARA, a FYVE domain protein that recruits Smad2 to the TGFβ receptor. Cell 95, 779-791.
    • (1998) Cell , vol.95 , pp. 779-791
    • Tsukazaki, T.1    Chiang, T.A.2    Davison, A.E.3    Attisano, L.4    Wrana, J.L.5
  • 32
    • 0033527733 scopus 로고    scopus 로고
    • Site-specific heterodimerization by paired class homeodomain proteins mediates selective transcriptional responses
    • Tucker, S.C. & Wisdom, R. (1999) Site-specific heterodimerization by paired class homeodomain proteins mediates selective transcriptional responses. J. Biol. Chem. 274, 32325-32332.
    • (1999) J. Biol. Chem , vol.274 , pp. 32325-32332
    • Tucker, S.C.1    Wisdom, R.2
  • 33
    • 0027332476 scopus 로고
    • Cooperative dimerization of paired class homeo domains on DNA
    • Wilson, D., Sheng, G., Lecuit, T., Dostatni, N. & Desplan, C. (1993) Cooperative dimerization of paired class homeo domains on DNA. Genes Dev. 7, 2120-2134.
    • (1993) Genes Dev , vol.7 , pp. 2120-2134
    • Wilson, D.1    Sheng, G.2    Lecuit, T.3    Dostatni, N.4    Desplan, C.5
  • 34
    • 0029946542 scopus 로고    scopus 로고
    • Prenatal folic acid treatment suppresses acrania and meroanencephaly in mice mutant for the Cart1 homeobox gene
    • Zhao, Q., Behringer, R.R. & de Crombrugghe, B. (1996) Prenatal folic acid treatment suppresses acrania and meroanencephaly in mice mutant for the Cart1 homeobox gene. Nature Genet. 13, 275-293.
    • (1996) Nature Genet , vol.13 , pp. 275-293
    • Zhao, Q.1    Behringer, R.R.2    de Crombrugghe, B.3
  • 35
    • 0027973640 scopus 로고
    • The gene for the homeodomain-contaning protein Cart-1 is expressed in cells that have a chondrogenic potential during embryonic development
    • Zhao, G.Q., Eberspaecher, H., Seldin, M.F. & de Crombrugghe, B. (1994) The gene for the homeodomain-contaning protein Cart-1 is expressed in cells that have a chondrogenic potential during embryonic development. Mech. Dev. 48, 245-254.
    • (1994) Mech. Dev , vol.48 , pp. 245-254
    • Zhao, G.Q.1    Eberspaecher, H.2    Seldin, M.F.3    de Crombrugghe, B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.