Extracellular zinc ion inhibits ClC-0 chloride channels by facilitating slow gating

Journal of General Physiology

Volumn 112, Issue 6, 1998, Pages 715-726

  Chen, Tsung Yu ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

ClC 0; Inactivation; Slow gating; Temperature dependence; Zn2+

Indexed keywords

CHLORIDE CHANNEL; ZINC ION;

ANIMAL CELL; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; DISSOCIATION CONSTANT; ELECTRIC ORGAN; ENTROPY; NONHUMAN; OOCYTE; TEMPERATURE DEPENDENCE; TORPEDO; XENOPUS LAEVIS;

ANIMALS; CATIONS, DIVALENT; CHLORIDE CHANNELS; FEMALE; ION CHANNEL GATING; KINETICS; MEMBRANE POTENTIALS; MODELS, BIOLOGICAL; OOCYTES; RECOMBINANT PROTEINS; TEMPERATURE; TORPEDO; XENOPUS; ZINC;

EID: 0032407783     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.112.6.715     Document Type: Article

References (32)

1. Backx, P.M., D.T. Yue, J.H. Lawrence, E. Marban, and G.F. Tomaselli. 1992. Molecular localization of an ion-binding site within the pore of mammalian sodium channels. Science. 257:248-251.
2. +]: a tale of two inactivation mechanisms. Neuron. 15:951-960.
3. + channel. Science. 271:653-656.
4. Bretag, A.H., M J. Fietz, and R.R.J. Bennet. 1984. The effects of zinc and other transition metal ions on rat skeletal muscle. Proc. Aust. Physiol. Pharmacol. Soc. 15:146P. (Abstr.)
5. - channel. J. Gen. Physiol. 108:237-250.
6. Clark, S., S.-E. Jordt, T.J. Jentsch, and A. Mathie. 1998. Characterization of the hyperpolarization-activated chloride current in dissociated rat sympathetic neurons. J. Physiol. (Lond.). 506:665-678.
7. Fong, P., A. Rehfeldt, and T.J. Jentsch. 1998. Determination of slow-gating in ClC-0, the voltage-gated chloride channel of Torpedo marmorata. Am. J. Physiol. 274:C966-C973.
8. Gordon, S.E., and W.N. Zagotta. 1995. A histidine residue associated with the gate of the cyclic nucleotide-activated channels in rod photoreceptors. Neuron. 14:177-183.
9. Hanke, W., and C. Miller. 1983. Single chloride channels from Torpedo electroplax: activation by protons. J. Gen. Physiol. 82:25-45.
10. Hille, B. 1992. Mechanisms of block. In Ion Channels of Excitable Membranes. 2nd ed. B. Hille, editor. Sinauer Associates, Inc. Sunderland, MA. 390-422.
11. Hutter, O.F., and A.E. Warner. 1967. Action of some foreign cations and anions on the chloride permeability of frog muscle. J. Physiol. (Lond.). 189:445-460.
12. Jentsch, T.J., K. Steinmeyer, and G. Schwarz. 1990. Primary structure of Torpedo mannorata chloride channel isolated by expression cloning in Xenopus oocytes. Nature. 348:510-514.
13. Karpen, J.W., R.L. Brown, L. Stryer, and D.A. Baylor. 1993. Interactions between divalent cations and the gating machinery of cyclic GMP-activated channels in salamander retinal rods. J. Gen. Physiol. 101:1-25.
14. 2+ and other sulfhydryl-reactive compounds. Pflügers Arch. 433:357-363.
15. + channel. Neuron. 19:175-184.
16. Ludewig, U., M. Pusch, and T.J. Jentsch. 1996. Two physically distinct pores in the dimeric ClC-0 chloride channel. Nature. 383:340-343.
17. Ludewig, U., T.J. Jentsch, and M. Pusch. 1997. Analysis of a protein region involved in permeation and gating of the voltage-gated Torpedo chloride channel ClC-0. J. Physiol. (Lond.). 498:691-702.
18. Middleton, R.E., D.J. Pheasant, and C. Miller. 1994. Purification, reconstitution, and subunit composition of a voltage-gated chloride channel from Torpedo electroplax. Biochemistry. 33:13189-13198.
19. Middleton, R.E., D.J. Pheasant, and C. Miller. 1996. Homodimeric architecture of a ClC-type chloride ion channel. Nature. 383:337-340.
20. Miller, C. 1982. Open-state substructure of single chloride channels from Torpedo electroplax. Philos. Trans. R. Soc. Lond. B Biol. Sci. 299:401-411.
21. Miller, C., and E.A. Richard. 1990. The voltage-dependent chloride channel of Torpedo electroplax: intimations of molecular structure from quirks of single-channel function. In Chloride Transporters. A. Leefmans and J. Russell, editors. Plenum Publishing Corp., New York. 383-405.
22. Miller, C., and M.M. White. 1984. Dimeric structure of single chloride channels from Torpedo electroplax. Proc. Natl. Acad. Sci. USA. 81:2772-2775.
23. Pusch, M., and T.J. Jentsch. 1994. Molecular physiology of voltage-gated chloride channels. Physiol. Rev. 74:813-825.
24. Pusch, M., U. Ludewig, and T.J. Jentsch. 1997. Temperature dependence of fast and slow gating relaxations of ClC-0 chloride channels. J. Gen. Physiol. 109:105-116.
25. Pusch, M., U. Ludewig, A. Rehfeldt, and T.J. Jentsch. 1995. Gating of the voltage-dependent chloride channel ClC-O by the permeantanion. Nature. 373:527-531.
26. Richard, E.A., and C. Miller. 1990. Steady-state coupling of ion-channel conformations to a transmembrane ion gradient. Science. 247:1208-1210.
27. 2+ and a carboxylate blocker with the rat ClC-1 chloride channel and its R304E mutant in the sf-9 insect cell line. J. Physiol. (Lond.). 498:691-702.
28. Stanfield, P.R. 1970. The differential effects of tetraethylammonium and zinc ions on the resting conductance of frog skeletal muscle. J. Physiol. (Lond.). 209:231-256.
29. Steinmeyer, K., C. Ortland, and T.J. Jentsch. 1991. Primary structure and functional expression of a developmentally regulated skeletal muscle chloride channel. Nature. 354:301-304.
30. + channels. J Gen. Physiol. 110:23-33.
31. White, M.M., and C. Miller. 1979. A voltage-gated anion channel from electric organ of Torpedo californica. J. Biol. Chem. 254:10161-10166.
32. + channel allows inactivation to be modulated by metal binding. Biophys. J. 66:1068-1075.