Induced sputum is a reproducible method to assess airway inflammation in asthma

Mediators of Inflammation

Volumn 11, Issue 5, 2002, Pages 293-298

  Bacci, Elena ^a   Cianchetti, Silvana ^a   Carnevali, Stefano ^a   Bartoli, Maria Laura ^a   Dente, Federico L ^a   Di Franco, Antonella ^a   Giannini, Daniele ^a   Vagaggini, Barbara ^a   Paggiaro, Pier Luigi ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

Airway inflammation; Bronchial asthma; Induced sputum

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; ASTHMA; CLINICAL ARTICLE; CORRELATION COEFFICIENT; EOSINOPHIL; HUMAN; INFLAMMATORY CELL; INFLAMMATORY DISEASE; LYMPHOCYTE; MACROPHAGE; NEUTROPHIL; PRIORITY JOURNAL; RELIABILITY; REPRODUCIBILITY; SPUTUM ANALYSIS; BRONCHUS HYPERREACTIVITY; CELL COUNT; CYTOLOGY; FEMALE; IMMUNOLOGY; MALE; MIDDLE AGED; PATHOLOGY; SALIVA; SPUTUM; STANDARD;

DIAGNOSTIC AGENT; SODIUM CHLORIDE;

ADOLESCENT; ADULT; AGED; ASTHMA; BRONCHIAL HYPERREACTIVITY; CELL COUNT; EOSINOPHILS; FEMALE; HUMANS; LYMPHOCYTES; MACROPHAGES; MALE; MIDDLE AGED; NEUTROPHILS; REPRODUCIBILITY OF RESULTS; SALINE SOLUTION, HYPERTONIC; SALIVA; SPUTUM;

EID: 0036809491     PISSN: 09629351     EISSN: None     Source Type: Journal    
DOI: 10.1080/09629350210000015692     Document Type: Article

References (20)

1. Pin I, Gibson PG, Kolendowicz R, et al. Use of induced sputum cell counts to investigate airway inflammation in asthma. Thorax 1992; 47: 25-29.
2. Pizzichini E, Pizzichini MMM, Efthimiadis A, et al. Indices of airway inflammation in induced sputum: Reproducibility and validity of cell and fluid-phase measurements. Am J Respir Crit Care Med 1996; 154: 308-317.
3. Spanevello A, Migliori GB, Sharara AM, et al. Induced sputum to assess airway inflammation: A study of reproducibility. Clin Exp Allergy 1997; 27: 1138-1144.
4. in't Veen JCCM, de Gouw HWFM, Smits HH, Sont JK, Hiemstra PS, Sterk PJ, Bel EH. Repeatability of cellular and soluble markers of inflammation in induced sputum from patients with asthma. Eur Respir J 1996; 9: 2441-2447.
5. Fahy JV, Boushey HA, Lazarus SC, et al. Safety and reproducibility of sputum induction in asthmatic subjects in a multicenter study. Am J Respir Crit Care Med 2001; 163: 1470-1475.
6. National heart, lung and blood institute. Global initiative for asthma. National Institutes of Health Publication No. 95-3659. January 1995.
7. Bacci E, Cianchetti S, Paggiaro PL, et al. Comparison between hypertonic and isotonic saline-induced sputum in the evaluation of airway inflammation in subjects with moderate asthma. Clin Exper Allergy 1997; 26: 1395-1400.
8. Fahy JV, Liu J, Wong H, Boushey HA. Cellular and biochemical analysis of induced sputum from asthmatic and from healthy subjects. Am Rev Respir Dis 1993; 147: 1126-1131.
9. Chinn S. Repeatability and method comparison. Thorax 1991; 46: 454-456.
10. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurements. Lancet 1986; i: 307-310.
11. Ward C, Gardiner PV, Booth H, Walters EH. Intrasubject variability in airway inflammation sampled by bronchoalveolar lavage in stable asthmatics. Eur Respir J 1995; 8: 1866-1871.
12. Wilson NM, Bridge P, Spanevello A, Silverman M. Induced sputum in children: Feasibility, repeatability and relation of findings to asthma severity. Thorax 2000; 55: 768-774.
13. Ward R, Woltmann G, Wardlaw AJ, Pavord ID. Between-observer repeatability of sputum differential cell counts. Influence of cell viability and squamous cell contamination. Clin Exp Allergy 1999; 29: 248-252.
14. Gershman NH, Wong HH, Liu JT, Mahlmeister MJ, Fahy JV. Comparison of two methods of collecting induced sputum in asthmatic subjects. Eur Respir J 1996; 9: 2448-2453.
15. Thomas PS, Yates DH, Barnes PJ. Sputum induction as a method of analyzing pulmonary cells: Reproducibility and acceptability. J Asthma 1999, 36: 335-341.
16. Holz O, Richter K, Jörres RA, Speckin P, Mücke M, Magnussen H. Changes in sputum composition between two inductions performed on consecutive days. Thorax 1998; 53: 83-86.
17. Nightingale JA, Rogers DF, Barnes PJ. Effect of repeated sputum induction on cell counts in normal volunteers. Thorax 1998; 53: 87-90.
18. Wong HH, Fahy JV. Safety of one method of sputum induction in asthmatic subjects. Am J Respir Crit Care Med 1997; 156: 299-303.
19. Claman DM, Boushey HA, Liu J, Wong H, Fahy JV. Analysis of induced sputum to examine the effects of prednisone on airway inflammation in asthmatic subjects. J Allergy Clin Immunol 1994; 94: 861-869.
20. Pizzichini MMM, Pizzichini E, Clelland L, et al. Sputum in severe exacerbations of asthma. Kinetics of inflammatory indices after prednisone treatment. Am J Respir Crit Care Med 1997; 155: 1501-1508.