Induced sputum to assess airway inflammation: A study of reproducibility

Clinical and Experimental Allergy

Volumn 27, Issue 10, 1997, Pages 1138-1144

  Spanevello, A ^a   Migliori, G B ^a   Sharara, A ^a   Ballardini, L ^b   Bridge, P ^a   Pisati, P ^a   Neri, M ^a   Ind, P W ^a  

^a IRCCS   (Italy)

^b HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

Asthma; Reproducibility; Rhinitis; Sputum induced

Indexed keywords

ADULT; ARTICLE; ASTHMA; CONTROLLED STUDY; CYTODIAGNOSIS; FEMALE; HUMAN; LABORATORY DIAGNOSIS; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; REPRODUCIBILITY; RESPIRATORY TRACT INFLAMMATION; RHINITIS; SPUTUM ANALYSIS;

ADULT; ALLERGENS; ASTHMA; BLOOD PROTEINS; BRONCHI; BRONCHIAL PROVOCATION TESTS; EOSINOPHIL GRANULE PROTEINS; EOSINOPHILS; EPITHELIAL CELLS; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; INFLAMMATION; LEUKOCYTE COUNT; LYMPHOCYTE COUNT; MACROPHAGES; MALE; METHACHOLINE CHLORIDE; MIDDLE AGED; NEUTROPHILS; REPRODUCIBILITY OF RESULTS; RHINITIS, ALLERGIC, SEASONAL; RIBONUCLEASES; SKIN TESTS; SPUTUM; VITAL CAPACITY;

EID: 0030865920     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2222.1997.tb01150.x     Document Type: Article

References (25)

1. Gibson PG, Girgis-Gabardo A, Morris MM et al. Cellular characteristics of sputum from patients with asthma and chronic bronchitis. Thorax 1989; 44:693-9.
2. Pin I, Gibson PG, Kolendovicz R et al. Use of induced sputum cell counts to investigate airway inflammation in asthma. Thorax 1992; 47:25-9.
3. Fahy JV, Liu J, Wong H, Boushey HA. Cellular and biochemical analysis of induced sputum from asthmatic and from healthy subjects. Am Rev Respir Dis 1993; 147:1126-31.
4. Iredale MJ, Wanklin SAR, Phillips IP, Krausz T, Ind PW. Non-Invasive assessment of bronchial inflammation inasthma: no correlation between eosinophilia of induced sputum and bronchial responsiveness to inhaled hypertonic saline. Clin Exp Allergy 1994; 24:940-5.
5. Popov T, Pizzichini MMM, Pizzichini E et al. Some technical factors influencing the induction of sputum for cell analysis. Eur Respir J 1995; 8:559-65.
6. Pizzichini E, Pizzichini MMM, Efthimiadis A et al. Indices of airway inflammation in induced sputum: reproducibility and validity of cell fluid-phase measurements. Am J Respir Crit Care Med 1996; 154:308-17.
7. Donner A, Eliasziw M. Sample size requirements for reliability studies. Statistics Medicine 1987; 6:441-8.
8. Quanjer PH (ed.), Report of Working Party. - European Community for Coal and Steel. Standardized lung function testing: 'Standardization of Lung Function Tests' Bull Eur Physiopathol Respir 1983; 19 ((Suppl. 5)): 7-87.
9. Global strategy for asthma management and prevention. National Institute of Health. National Heart, Lung, Blood Institute 1995; 95-3659.
10. Aas K. Heterogeneity of bronchial asthma: sub-populations or different stages of the disease. Allergy 1981; 36:3-10.
11. Dixon CMS, Ind PW. Inhaled sodium metabisulphite induced bronchocostriction: inhibition by nedocromil sodium and sodium cromoglycate. Br J Clin Pharmacol 1990; 30:371-6.
12. Saetta M, Di Stefano A, Hosselet JJ et al. Sputum eosinophilia after asthmatic responses induced by isocyanates in sensitized subjects. Clin Exp Allergy 1994; 24:29-34.
13. Efthimiadis A, Hussack P, Evans S et al. Spontaneous and induced to measure indices of airway inflammation in asthma. Am J Respir Crit Care Med 1996; 154:866-89.
14. Fleiss JL. The design and analysis of clinical experiments. John Wiley and Sons, 1986; 8-13.
15. Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics 1977; 33:159-74.
16. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986; i:307-10.
17. Dolovich J, Powers P, Hargreave FE. The evaluation of a cell dispersion method of sputum examination. Clin Exp Allergy 1994; 24:778-83.
18. Mastropasqua B, Chetta A, D'Ippolito R, Marazzini L, Olivieri D. Mast cells, Basophils and Eosinophils in induced sputum from patients with seasonal allergic rhinitis (AR) and perennial asthma (AS): relationship to methacholine responsiveness. Am J Respir Crit Care Med 1996; 154:A291.
19. Wirchow JC, Holscher U, Wirchow Sr. Sputum ECP levels correlate with parameters of airflow obstruction. Am Rev Respir Dis 1993; 146:604-6.
20. Efthimiadis A, Hargreave FE, Dolovich J. Measurement of inflammatory indices in induced sputum: effects of selection of sputum to minimize salivary contamination. Eur Respir J 1996; 9:1174-80.
21. Paré PD, James A, Hogg JC. A model of airway narrowing in asthma and in chronic obstructive pulmonary disease. Am Rev Respir Dis 1991; 145:1251-8.
22. Skloot G, Permutt S, Togias AG. Airway hyperresponsiveness in asthma: a problem of limited smooth muscle relaxation with inspiration. J Clin Invest 1995; 96:2393-403.
23. Pin I, Freitag AG, O'Byrne PM et al. Changes in the cellular profile of induced sputum after allergen-induced asthmatic responses. Am Rev Respir Dis 1992; 145:1265-9.
24. Claman DM, Boushey HA, Liu J, Wong H, Fahy JV. Analysis of induced sputum to examine the effects of prednisone on airway inflammation. J Allergy Clin Immunol 1994; 94:861-9.
25. Fahy JV, Wong H, Liu J, Boushey HA. Analysis of cellular and biochemical constituents of induced sputum after allergen challenge: a method for studying allergic airway inflammation. J Allergy Clin Immunol 1994; 93:1031-9.