The -4,752 C/T polymorphism in the presenilin 1 gene increases the risk of alzheimer's disease in apolipoprotein E4 carriers

Internal Medicine

Volumn 41, Issue 10, 2002, Pages 823-828

  Matsubara Tsutsui, Miho ^a,b,c   Yamagata, Hidehisa ^a,b,c   Morishima, Atsuyuki ^a,b,c   Nakura, Jun ^a,b,c   Mitsuda, Noriaki ^a,b,c   Kamino, Kouzin ^a,b,c   Kondo, Ikuko ^a,b,c   Miki, Tetsuro ^a,b,c  

^a Department of Geriatric Medicine ^*  (Japan)

^b EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

4,752 C T; APOE; Haplotype; Promoter region; Risk factor

Indexed keywords

APOLIPOPROTEIN E4; CARRIER PROTEIN; CYTOSINE; DNA FRAGMENT; PRESENILIN 1; THYMINE;

AGED; ALLELE; ALZHEIMER DISEASE; ARTICLE; COMPUTER PROGRAM; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE FREQUENCY; GENE SEQUENCE; GENETIC RISK; GENETIC SCREENING; GENOTYPE; HAPLOTYPE; HETEROZYGOSITY; HUMAN; JAPAN; MAJOR CLINICAL STUDY; MALE; MARKER GENE; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PLASMID; PROMOTER REGION; RISK ASSESSMENT;

EID: 0036808069     PISSN: 09182918     EISSN: None     Source Type: Journal    
DOI: 10.2169/internalmedicine.41.823     Document Type: Article

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