BRCA1 interacts directly with the Fanconi anemia protein FANCA

Human Molecular Genetics

Volumn 11, Issue 21, 2002, Pages 2591-2597

  Folias, Alexandra ^a   Matkovic, Mara ^a   Bruun, Donald ^a   Reid, Sonja ^a   Hejna, James ^a   Grompe, Markus ^a,b   D'Andrea, Alan ^c   Moses, Robb ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; BRCA1 PROTEIN; CELL EXTRACT; CELL PROTEIN; DNA; DOUBLE STRANDED DNA; FANCONI ANEMIA GROUP A PROTEIN; NUCLEIC ACID BINDING PROTEIN; UNCLASSIFIED DRUG;

ANEMIA; ARTICLE; AUTOSOMAL RECESSIVE DISORDER; CANCER RISK; CELL CYCLE S PHASE; CELL NUCLEUS; CHROMOSOME ABERRATION; CONTROLLED STUDY; DNA CROSS LINKING; DNA DAMAGE; DNA REPAIR; FANCONI ANEMIA; HUMAN; IMMUNOPRECIPITATION; IN VITRO STUDY; LEUKEMIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; SKELETON MALFORMATION; TWO HYBRID SYSTEM;

BACTERIA (MICROORGANISMS);

EID: 0036799765     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/11.21.2591     Document Type: Article

References (30)

1. Joenje, H. and Patel, K.J. (2001) The emerging genetic and molecular basis of Fanconi anaemia. Nature Rev. Genet., 2, 446-457.
2. Grompe, M. and D'Andrea, A.D. (2001) Fanconi anemia and DNA repair. Hum. Mol. Genet., 10, 2253-2259.
3. Joenje, H., Oostra, A.B., Wijker, M., di Summa, F.M., van Berkel, C.G., Rooimans, M.A., Ebell, W, van Weel, M., Pronk, J.C., Buchwald, M. et al. (1997) Evidence for at least eight Fanconi anemia genes. Am. J. Hum. Genet., 61, 940-944.
4. Strathdee, C.A., Gavish, H., Shannon, W.R. and Buchwald, M.(1992) Cloning of cDNAs for Fanconi anemia by functional complementation. Nature, 359, 763-767.
5. Lo Ten Foe, J.R., Rooimans, M.A., Bosnoyan-Collins, L., Alon, N., Wijker, M., Parker, L., Lightfoot, J., Carreau, M., Callen, D.F, Savoia, A. et al. (1996) Expression cloning of a cDNA for the major Fanconi anaemia gene, FAA. Nature Genet., 14, 320-323.
6. Fanconi Anemia/Breast Cancer Consortium (1996) Positional cloning of the Fanconi anemia group A gene. Nature Genet., 14, 324-328.
7. de Winter, J.P., Waisfisz, Q., Rooimans, M.A., van Berkel, C.G., Bosnoyan-Collins, L., Alon, N., Carreau, M., Bender, O., Demuth, I., Schindler, D. et al. (1998) The Fanconi anemia group G gene FANCG is identical with XRCC9. Nature Genet., 20, 281-283.
8. de Winter, J.P., Leveille, F., van Berkel, C.G., Rooimans, M.A., van Der Weel, L., Steltenpool, J., Demuth, I., Morgan, N.V, Alon, N., Bosnoyan-Collins, L. et al. (2000) Isolation of a cDNA representing the Fanconi anemia complementation group E gene. Am. J. Hum. Genet., 67, 1306-1308.
9. de Winter, J.P., Rooimans, M.A., van Der Weel, L., van Berkel, C.G., Alon, N., Bosnoyan-Collins, L., de Groot, J., Zhi, Y., Waisfisz, Q., Pronk, J.C. et al. (2000) The Fanconi anaemia gene FANCF encodes a novel protein with homology to ROM. Nat Genet., 24, 15-16.
10. Timmers, C., Taniguchi, T., Hejna, J., Reifsteck, C., Lucas, L., Bruun, D., Thayer, M., Cox, B., Olson, S., D'Andrea, A.D. et al. (2001) Positional Cloning of a novel Fanconi anemia gene, FANCD2. Mol. Cell, 7, 241-248.
11. Garcia-Higuera, I., Kuang, Y., Naf, D., Wasik, J. and D'Andrea, A.D. (1999) Fanconi anemia proteins FANCA, FANCC, and FANCG/XRCC9 interact in a functional nuclear complex. Mol. Cell Biol., 19, 4866-4873.
12. Waisfisz, Q., de Winter, J.R, Kruyt, F.A., de Groot, J., van der Weel, L., Dijkmans, L.M., Zhi, Y, Arwert, E, Scheper, R.J., Youssoufian, H. et al. (1999) A physical complex of the Fanconi anemia proteins EANCG/XRCC9 and FANCA. Proc. Natl Acad. Sci. USA, 96, 10320-10325.
13. de Winter, J.P., van der Weel, L., de Groot, J., Stone, S., Waisfisz, Q., Arwert, E, Scheper, R.J., Kruyt, F.A., Hoatlin, M.E. and Joenje, H. (2000) The Fanconi anemia protein FANCF forms a nuclear complex with FANCA, FANCC and FANCG. Hum. Mol. Genet., 9, 2665-2674.
14. Yamashita, T., Kupfer, G.M., Naf, D., Suliman, A., Joenje, H., Asano, S. and D'Andrea, A.D. (1998) The Fanconi anemia pathway requires FAA phosphorylation and FAA/FAC nuclear accumulation. Proc. Natl Acad. Sci. USA, 95, 13085-13090.
15. Medhurst, A.L., Huber, P.A., Waisfisz, Q., de Winter, J.P. and Mathew, C.G. (2001) Direct interactions of the five known Fanconi anaemia proteins suggest a common functional pathway. Hum. Mol. Genet., 10, 423-429.
16. Garcia-Higuera, I., Taniguchi, T., Ganesan, S., Meyn, M.S., Timmers, C., Hejna, J., Grompe, M. and D'Andrea, A.D. (2001) Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway. Mol. Cell, 7, 249-262.
17. Welcsh, P., Owens, K.N. and King, M.C. (2000) Insights into the functions of BRCA1 and BRCA2. Trends Genet., 16, 69-74.
18. Venkitaraman, A.R. (2002) Cancer susceptibility and the functions of BRCA1 and BRCA2. Cell, 108, 171-182.
19. Scully, R., Ganesan, S., Vlasakova, K., Chen, J., Socolovsky, M. and Livingston, D.M. (1999) Genetic analysis of BRCA1 function in a defined tumor cell line. Molec. Cell, 4, 1093-1099.
20. Scully, R., Chen, J., Plug, A., Xiao, Y., Weaver, D., Feunteun, J., Ashley, T. and Livingston, D.M. (1997) Association of BRCA1 with Rad51 in mitotic and meiotic cells. Cell, 88, 265-275.
21. Wang, Y., Cortez, D., Yazdi, R, Neff, N., Elledge, S.J. and Qin, J. (2000) BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Genes & Devel., 14, 927-939.
22. Fields, S. and Song, O. (1989) A novel genetic system to detect protein-protein interactions. Nature, 340, 245-246.
23. Castilla, L.H., Couch, F.J., Erdos, M.R., Hoskins, K.F., Calzone, K., Garber, J.E. Boyd, J., Lubin, M.B., Deshano, M.L., Brody, L.C. et al. (1994) Mutations in the BRCA1 gene in families with early-onset breast and ovarian cancer. Nature Genet., 8, 387-391.
24. Naf, D., Kupfer, G.M., Suliman, A., Lambert, K. and D'Andrea, A.D. (1998) Functional activity of the Fanconi anemia protein FAA requires FAC binding and nuclear localization. Mol. Cell Biol., 18, 5952-5960.
25. Hoatlin, M.E., Zhi, Y., Ball, H., Silvey, K., Melnick, A., Stone, S., Hawe, N., Owen, N.G., Zelent, A. and Licht, J.D. (1999) A novel BTB/POZ transcriptional repressor protein interacts with the Fanconi anemia group C protein and PLZF. Blood, 94, 3737-3747.
26. Otsuki, T., Furukawa, Y., Ikeda, K., Endo, H., Yamashita, T., Shinohara, A., Iwamatsu, A., Ozawa, K. and Liu, J.M. (2001) Fanconi anemia protein, FANCA, associates with BRG1, a component of the human SWI/SNF complex. Hum. Mol. Genet., 10, 2651-2660.
27. Futaki, M. and Liu, J.M. (2001) Chromosomal breakage syndromes and the BRCA1 genome surveillance complex. Trends Mol. Med., 7, 560-565.
28. Joazeiro, C.A.P. and Weissman, A.M. (2000) RING finger proteins: mediators of ubiquitin ligase activity. Cell, 102, 549-552.
29. Grossmann K.F., Ward, A.M., Matkovic, M.E., Folias, A.E. and Moses, R.E. (2001) S. cerevisiae has three pathways for DNA interstrand crosslink repair. Mutation Res., 487, 73-83.
30. Gietz, D.R. and Woods, R.A. (2001) Genetic transformation of yeast. BioTechniques, 30, 816-831.