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Volumn 77, Issue 10, 2002, Pages 1122-1126

Employing racemic precursors in directed biosynthesis of 6-dEB analogs

Author keywords

6 Deoxyerythronolide B; Precursor directed biosynthesis; Racemic precursor; Streptomyces coelicolor

Indexed keywords

BIOSYNTHESIS; ESTERS; FERMENTATION; SUBSTRATES; TOXICITY;

EID: 0036799062     PISSN: 02682575     EISSN: None     Source Type: Journal    
DOI: 10.1002/jctb.685     Document Type: Article
Times cited : (9)

References (8)
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    • Katz, L.1    McDaniel, L.2
  • 2
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    • Precursor-directed biosynthesis of erythromycin analogs by an engineered polyketide synthase
    • Jacobsen JR, Hutchinson CR, Cane DE and Khosla C, Precursor-directed biosynthesis of erythromycin analogs by an engineered polyketide synthase. Science 227:367-369 (1997).
    • (1997) Science , vol.227 , pp. 367-369
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  • 3
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    • Precursor-directed production of erythromycin analogs by Saccharopolyspora erythraea
    • Frykman S, Leaf T, Carreras C and Licari P, Precursor-directed production of erythromycin analogs by Saccharopolyspora erythraea. Biotechnology and Bioengineering 76:303-310 (2001).
    • (2001) Biotechnology and Bioengineering , vol.76 , pp. 303-310
    • Frykman, S.1    Leaf, T.2    Carreras, C.3    Licari, P.4
  • 4
    • 0034233473 scopus 로고    scopus 로고
    • Precursor-directed biosynthesis of 6-deoxyerythronolide B analogs in Streptomyces coelicolor: Understanding precursor effects
    • Leaf T, Cadapan L, Carreras C, Regentin R, Ou S, Woo E, Ashley G and Licari P, Precursor-directed biosynthesis of 6-deoxyerythronolide B analogs in Streptomyces coelicolor: understanding precursor effects. Biotechnol Prog 16:553-556 (2000).
    • (2000) Biotechnol Prog , vol.16 , pp. 553-556
    • Leaf, T.1    Cadapan, L.2    Carreras, C.3    Regentin, R.4    Ou, S.5    Woo, E.6    Ashley, G.7    Licari, P.8
  • 6
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    • Engineered biosynthesis of a complete macrolactone in a heterologous host
    • Kao CM, Katz L and Khosla C, Engineered biosynthesis of a complete macrolactone in a heterologous host. Science 265:509-512 (1994).
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    • Kao, C.M.1    Katz, L.2    Khosla, C.3
  • 7
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    • Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of novel 'unnatural' natural products
    • McDaniel RA, Thamchaipenet A, Gustafsson C, Fu H, Betlach M, Betlach M and Ashley G, Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of novel 'unnatural' natural products. Proc Nat Acad Sci 96:1846-1851 (1999).
    • (1999) Proc Nat Acad Sci , vol.96 , pp. 1846-1851
    • McDaniel, P.A.1    Thamchaipenet, A.2    Gustafsson, C.3    Fu, H.4    Betlach, M.5    Betlach, M.6    Ashley, G.7
  • 8
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    • Analysis of the molecular recognition features of individual modules derived from the erythromycin polyketide synthase
    • Wu N, Kudo F, Cane DE and Khosla C, Analysis of the molecular recognition features of individual modules derived from the erythromycin polyketide synthase. J Am Chem Soc 122:4847-4852.
    • (2000) J Am Chem Soc , vol.122 , pp. 4847-4852
    • Wu, N.1    Kudo, F.2    Cane, D.E.3    Khosla, C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.