Flaws in design and conduct of clinical trials in acute otitis media

Pediatric Infectious Disease Journal

Volumn 21, Issue 10, 2002, Pages 894-902

  Dagan, Ron ^a   McCracken Jr , George H ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

Acute otitis media; Antimicrobial; Clinical trial; Design; Outcome; Risk factors

Indexed keywords

AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID; ANTIBIOTIC AGENT; AZITHROMYCIN; BETA LACTAM ANTIBIOTIC; CEFACLOR; CEFPROZIL; CEFTRIAXONE; CEFUROXIME AXETIL; CLARITHROMYCIN; COTRIMOXAZOLE; MACROLIDE; PENICILLIN G; PLACEBO;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC SENSITIVITY; ANTIBIOTIC THERAPY; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; ERADICATION THERAPY; HAEMOPHILUS INFLUENZAE; HUMAN; INFANT; META ANALYSIS; MINIMUM INHIBITORY CONCENTRATION; MORAXELLA CATARRHALIS; OTITIS MEDIA; OUTCOMES RESEARCH; PRIORITY JOURNAL; REVIEW; RISK FACTOR; SAMPLING; STREPTOCOCCUS PNEUMONIAE; SYMPTOMATOLOGY; TREATMENT FAILURE;

ACUTE DISEASE; ANTI-BACTERIAL AGENTS; CHILD; CHILD, PRESCHOOL; CLINICAL TRIALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; INFANT; MALE; OTITIS MEDIA; PATIENT SELECTION; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TREATMENT OUTCOME; UNITED STATES;

EID: 0036796203     PISSN: 08913668     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006454-200210000-00003     Document Type: Review

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