Effects of Mannich bases on cellular glutathione and related enzymes of Jurkat cells in culture conditions

Toxicology in Vitro

Volumn 16, Issue 2, 2002, Pages 107-112

  Gul, M ^a,b   Gul, H I ^a,c   Hanninen O ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b ATATURK UNIVERSITY   (Turkey)

^c ATATÜRK UNIVERSITY   (Turkey)

Author keywords

Acetophenone; Glutathione; Glutathione related enzymes; Jurkat cells; Mannich base

Indexed keywords

ENZYME; GLUTATHIONE; GLUTATHIONE DISULFIDE REDUCTASE; GLUTATHIONE TRANSFERASE; MANNICH BASE; THIOL; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; ATMOSPHERE; CATTLE; CELL CULTURE; CELL LEVEL; CELL METABOLISM; CONJUGATION; CONTROLLED STUDY; DETOXIFICATION; ENZYME ACTIVATION; ENZYME ACTIVITY; FEEDBACK SYSTEM; GLUTATHIONE METABOLISM; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; NUTRIENT; RECEPTOR UPREGULATION; TEMPERATURE; TIME;

ACETOPHENONES; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; HUMANS; JURKAT CELLS; MANNICH BASES; NADH, NADPH OXIDOREDUCTASES;

BOVINAE;

EID: 0036182459     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0887-2333(01)00115-1     Document Type: Article

References (21)

1. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
2. Glutathione reductase
3. Evaluation of cytotoxicity of some Mannich bases of various aryl and arylidene ketones and their corresponding arylhydrazones
4. Nuclear-substituted styryl ketone analogs: Effects on neoplasms, microorganisms, and mitochondrial respiration of tumorous and normal cells
5. Cytotoxic activities of Mannich bases of chalcones and related compounds
6. Anticancer and cytotoxic properties of Mannich bases
7. Activity of some Mannich bases of conjugated styryl ketones against Candida albicans
8. bis-Mannich bases of styryl ketones as antileukemic agents
9. Antimicrobial evaluation of some styryl ketone derivatives and related thiol adducts
10. Synthesis of Mannich bases of 5-hydroxynapthalene-1,8-carbolactone as potential antifungal or antitumor agents
11. Assays of glutathione peroxidase
12. Cytotoxic activities of mono and bis Mannich bases derived from acetophenone against Renca and Jurkat cells
13. Cellular and clinical implications of glutathione
14. Antifungal activity of some mono, bis and quaternary Mannich bases derived from acetophenone
15. Effect of acetophenone derived Mannich bases on cellular glutathione level in Jurkat cells: A possible mechanism of action
16. Glutathione S-transferases. The first enzymatic step in mercapturic acid formation
17. Proton-pumping-ATPase-targeted antifungal activity of a novel conjugated styryl ketone
18. 1,3,4-Trisubstituted piperidine derivatives from Mannich bases
19. The reaction of acetophenone with formaldehyde and methylamine hydrochloride
20. A spectrophotometric glutathione S-transferase assay displaying alpha-class selectivity utilizing 1-p-chlorophenyl-4,4-dimethyl-5-diethylamino-1-penten-3- one hydrobromide
21. Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues