Prediction of an HMG-box fold in the C-terminal domain of histone H1: Insights into its role in DNA condensation

Proteins: Structure, Function and Genetics

Volumn 49, Issue 1, 2002, Pages 71-81

  Bharath, M M Srinivas ^a   Chandra, Nagasuma R ^a   Rao, M R S ^a  

^a INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

C terminal domain; Chromatin organization; DNA condensation; Histone H1; HMG box fold

Indexed keywords

CELL DNA; HIGH MOBILITY GROUP PROTEIN; HISTONE H1; LYMPHOID ENHANCER FACTOR 1; PROTEIN; TESTIS DETERMINING FACTOR; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CHROMATIN CONDENSATION; PREDICTION; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN FOLDING; PROTEIN MOTIF; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; CHROMATIN; DNA; HIGH MOBILITY GROUP PROTEINS; HISTONES; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; RATS; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, PROTEIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EUKARYOTA;

EID: 0036782182     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/prot.10204     Document Type: Article

References (54)

1. Three-dimensional structure of extended chromatin fibers as revealed by tapping mode scanning microscopy
2. Crystal structure of the nucleosomal core particle at 2.8Å resolution
3. Electrostatic mechanism of chromatin folding
4. Regulation of higher-order structure of chromatin by histones H1 and H5
5. α-helix in the carboxy terminal domains of histone H1 and H5
6. Homo- and heteronuclear two-dimensional NMR studies of the globular domain of histone H1: Sequential assignment and secondary structure
7. Crystal structure of globular domain of histone H5 and its implications for nucleosome binding
8. Condensation of DNA by the C-terminal domain of histone H1: A circular dichroism study
9. Linker histones are not essential and affect chromatin compaction in vivo
10. Protein structure prediction and structural genomics
11. Progress in protein structure prediction
12. GGDEF domain is homologous to adenylyl cyclase
13. CLUSTALW improving the sensitivity of progressive multiple sequence alignment through sequence weighing, position-specific gap penalties and weight matrix choice
14. PRINTS - A protein motif fingerprint database
15. NPS@: Network protein sequence analysis
16. GOR secondary structure prediction method version IV
17. (MLRC): Improved performance in protein secondary structure prediction by inhomogeneous score combination
18. PHD: Predicting one-dimensional protein structure by profile based neural networks
19. Incorporation of non-local interactions in protein secondary structure prediction from the amino acid sequence
20. SOPM: A self-optimized method for protein secondary structure prediction
21. The 2000 Olympic Games of protein structure prediction; fully automated programs are being evaluated vis-a-vis human teams in the protein structure prediction experiment CAFASP2
22. Successful protein fold recognition by optimal sequence threading validated by rigorous blind testing
23. Hybrid fold recognition: Combining sequence derived properties with evolutionary information
24. Enhanced genome annotation using structural profiles in the program 3D-PSSM
25. SCOP: A structural classification of proteins database for the investigation of sequences and structures
26. Mapping the protein universe
27. A graphics model building and refinement system for macromolecules
28. The Pfam protein families database
29. Recent improvements to the SMART domain-based sequence annotation resource
30. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
31. The COG database: New developments in phylogenetic classification of proteins from complete genomes
32. Condensation of DNA and chromatin by an SPKK containing octapeptide repeat motif present in the C-terminus of Histone H1
33. Identification of a 34 amino acid stretch within the C-terminus of histone H1 as the DNA condensing domain by site directed mutagenesis
34. High mobility group chromosomal proteins: Architectural components that facilitate chromatin function
35. Linker histones versus HMG1/2: A struggle for dominance
36. Domain structure in high molecular weight group non histone chromatin proteins
37. The DNA-bending protein HMG-1 enhances progesterone receptor binding to its target DNA sequences
38. An NMR study on the DNA binding SPKK motif and a model for its interaction with DNA
39. Structural basis for DNA bending by the architectural transcription factor LEF1
40. A helix-turn motif in the C-terminal domain of histone H1
41. Induction of secondary structure in A-COOH terminal peptide of histone H1 by interaction with DNA: An infrared spectroscopy
42. Molecular basis of human 46 x,y sex reversal revealed from the three-dimensional solution structure of the human SRY-DNA complex
43. The structure of a chromosomal high mobility group protein DNA complex reveals sequence-neutral mechanisms important for non-sequence-specific DNA recognition
44. Structural modification of DNA by a DNA-binding motif SPKK: Detection of changes in base-pair hydrogen bonding and base stacking by UV-resonance Raman spectroscopy
45. What determines the folding of chromatin fibre?
46. Dinuclesomes show compaction by ionic strength, consistent with bending of linker DNA
47. Direct detection of linker DNA bending in defined length oligomers of chromatin
48. The recognition of distorted DNA structure by HMG-D: A foot printing and molecular modeling study
49. Linker histones inhibit T4 and Escherichia coli DNA ligases
50. DNA chromatin condensing properties of rat testes H1a and H1t compared to those of rat liver H1 bdec: H1t is a poor condenser of chromatin
51. Preferential condensation of SAR-DNA by histone H1 and its SPKK containing octapeptide repeat motif
52. Linker histone-dependent DNA structure in linear mononucleosomes
53. Chromatin architectural proteins and transcription factors: A structural connection