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Volumn 62, Issue 3, 2002, Pages 521-528

A fusion protein of the human P2Y1 receptor and NTPDase1 exhibits functional activities of the native receptor and ectoenzyme and reduced signaling responses to endogenously released nucleotides

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE 5' O (2 THIODIPHOSPHATE); ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 1; HYBRID PROTEIN; HYDROLASE; INOSITOL PHOSPHATE; NUCLEOTIDASE; NUCLEOTIDE; PHOSPHOLIPASE C; PURINE P2Y RECEPTOR; UNCLASSIFIED DRUG;

EID: 0036765784     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.62.3.521     Document Type: Article
Times cited : (13)

References (31)
  • 1
    • 0032928118 scopus 로고    scopus 로고
    • Detection of local ATP release from activated platelets using cell surface-attached firefly luciferase
    • Beigi R, Kobatake M, Aizawa M, and Dubyak GR (1999) Detection of local ATP release from activated platelets using cell surface-attached firefly luciferase. Am J Physiol 276:267-278.
    • (1999) Am J Physiol , vol.276 , pp. 267-278
    • Beigi, R.1    Kobatake, M.2    Aizawa, M.3    Dubyak, G.R.4
  • 2
    • 0031466317 scopus 로고    scopus 로고
    • Molecular cloning and expression of an avian G protein-coupled P2Y receptor
    • Boyer JL, Waldo GL, and Harden TK (1997) Molecular cloning and expression of an avian G protein-coupled P2Y receptor. Mol Pharmacol 52:928-934.
    • (1997) Mol Pharmacol , vol.52 , pp. 928-934
    • Boyer, J.L.1    Waldo, G.L.2    Harden, T.K.3
  • 3
    • 0035794120 scopus 로고    scopus 로고
    • Cystic fibrosis transmembrane conductance regulator facilitates ATP release by stimulating ATP release channel for autocrine control of cell volume regulation
    • Braunstein GM, Roman R, Clancy J, Kudlow B, Taylor A, Shylonsky V, Jovov B, Peter C, Jilling T, Ismailov I, et al. (2001) Cystic fibrosis transmembrane conductance regulator facilitates ATP release by stimulating ATP release channel for autocrine control of cell volume regulation. J Biol Chem 276:6621-6630.
    • (2001) J Biol Chem , vol.276 , pp. 6621-6630
    • Braunstein, G.M.1    Roman, R.2    Clancy, J.3    Kudlow, B.4    Taylor, A.5    Shylonsky, V.6    Jovov, B.7    Peter, C.8    Jilling, T.9    Ismailov, I.10
  • 4
    • 0027661421 scopus 로고
    • 2-purinergic receptors for extracellular ATP and other nucleotides
    • 2-purinergic receptors for extracellular ATP and other nucleotides. Am J Physiol 265:C577-C606.
    • (1993) Am J Physiol , vol.265
    • Dubyak, G.R.1    El-Moatassim, C.2
  • 8
    • 0030989580 scopus 로고    scopus 로고
    • CFTR-independent ATP release from epithelial cells triggered by mechanical stimuli
    • Grygorczyk R and Hanrahan JW (1997) CFTR-independent ATP release from epithelial cells triggered by mechanical stimuli. Am J Physiol 272:C1058-C1066.
    • (1997) Am J Physiol , vol.272
    • Grygorczyk, R.1    Hanrahan, J.W.2
  • 11
    • 0000969898 scopus 로고    scopus 로고
    • Pharmacological selectivities of molecularly defined subtypes of P2Y receptors
    • (Turner JT, Weisman, GA and Fedan JS eds), Humana Press, Totowa, NJ
    • Harden TK, Nicholas RA, Scachter JB, Lazarowski ER, and Boyer JL (1998b) Pharmacological selectivities of molecularly defined subtypes of P2Y receptors, in The P2 Nucleotide Receptors (Turner JT, Weisman, GA and Fedan JS eds) pp 109-134, Humana Press, Totowa, NJ.
    • (1998) The P2 Nucleotide Receptors , pp. 109-134
    • Harden, T.K.1    Nicholas, R.A.2    Scachter, J.B.3    Lazarowski, E.R.4    Boyer, J.L.5
  • 12
    • 0035923676 scopus 로고    scopus 로고
    • Compartmentalized autocrine signaling to cystic fibrosis transmembrane conductance regulator at the apical membrane of airway epithelial cells
    • Huang P, Lazarowski ER, Tarran R, Milgram SL, Boucher HC, and Stutts MJ (2001) Compartmentalized autocrine signaling to cystic fibrosis transmembrane conductance regulator at the apical membrane of airway epithelial cells. Proc Natl Acad Sci USA 98:14120-14125.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 14120-14125
    • Huang, P.1    Lazarowski, E.R.2    Tarran, R.3    Milgram, S.L.4    Boucher, H.C.5    Stutts, M.J.6
  • 13
    • 0034193130 scopus 로고    scopus 로고
    • Using green fluorescent proteins to study G-protein-coupled receptor localization and trafficking
    • Kallal L and Benovic JL (2000) Using green fluorescent proteins to study G-protein-coupled receptor localization and trafficking. Trends Pharmacol Sci 21:175-180.
    • (2000) Trends Pharmacol Sci , vol.21 , pp. 175-180
    • Kallal, L.1    Benovic, J.L.2
  • 18
    • 0034857737 scopus 로고    scopus 로고
    • Interplay of constitutively released nucleotides, nucleotide metabolism and activity of PY receptor
    • Lazarowski E, Boucher RC, and Harden TK (2001) Interplay of constitutively released nucleotides, nucleotide metabolism and activity of PY receptor. Drug Dev Res 53:66-71
    • (2001) Drug Dev Res , vol.53 , pp. 66-71
    • Lazarowski, E.1    Boucher, R.C.2    Harden, T.K.3
  • 19
    • 0032803745 scopus 로고    scopus 로고
    • Quantitation of extracellular UTP using a sensitive enzymatic assay
    • Lazarowski ER and Harden TK (1999) Quantitation of extracellular UTP using a sensitive enzymatic assay. Br J Pharmacol 127:1272-1278.
    • (1999) Br J Pharmacol , vol.127 , pp. 1272-1278
    • Lazarowski, E.R.1    Harden, T.K.2
  • 20
    • 0034613299 scopus 로고    scopus 로고
    • Constitutive release of ATP and evidence for major contribution of ecto-nucleotide pyrophosphaase and nucleoside diphosphokinase to extracellular nucleotide concentrations
    • Lazarowski ER, Boucher RC, and Harden TK (2000) Constitutive release of ATP and evidence for major contribution of ecto-nucleotide pyrophosphaase and nucleoside diphosphokinase to extracellular nucleotide concentrations. J Biol Chem 275:31061-31068.
    • (2000) J Biol Chem , vol.275 , pp. 31061-31068
    • Lazarowski, E.R.1    Boucher, R.C.2    Harden, T.K.3
  • 21
    • 0030882314 scopus 로고    scopus 로고
    • Direct demonstration of mechanically induced release of cellular UTP and its implication for uridine nucleotide receptor activation
    • Lazarowski ER, Homolya L, Boucher RC, and Harden TK (1997) Direct demonstration of mechanically induced release of cellular UTP and its implication for uridine nucleotide receptor activation. J Biol Chem 372:24348-24354.
    • (1997) J Biol Chem , vol.372 , pp. 24348-24354
    • Lazarowski, E.R.1    Homolya, L.2    Boucher, R.C.3    Harden, T.K.4
  • 24
    • 0034697314 scopus 로고    scopus 로고
    • Cellular release of and response to ATP as key determinants of the set-point of signal transduction pathways
    • Ostrom RS, Gregorian C, and Insel PA (2000) Cellular release of and response to ATP as key determinants of the set-point of signal transduction pathways. J Biol Chem 275:11735-11739.
    • (2000) J Biol Chem , vol.275 , pp. 11735-11739
    • Ostrom, R.S.1    Gregorian, C.2    Insel, P.A.3
  • 25
    • 0031754497 scopus 로고    scopus 로고
    • Receptors for purines and pyimidines
    • Ralevic V and Burnstock G (1998) Receptors for purines and pyimidines. Pharmacol Rev 50:413-492.
    • (1998) Pharmacol Rev , vol.50 , pp. 413-492
    • Ralevic, V.1    Burnstock, G.2
  • 27
    • 0029815856 scopus 로고    scopus 로고
    • Isolated rat hepatocytes can signal to other hepatocytes and bile duct cells by release of nucleotides
    • Schlosser SF, Burgstahler AD, and Nathanson MH (1996) Isolated rat hepatocytes can signal to other hepatocytes and bile duct cells by release of nucleotides. Proc Natl Acad Sci USA 93:9948-9953.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 9948-9953
    • Schlosser, S.F.1    Burgstahler, A.D.2    Nathanson, M.H.3
  • 28
    • 0343114345 scopus 로고    scopus 로고
    • 1 receptor tagged with green-fluorescent protein: High-affinity ligand recognition of adenosine diphosphates and triphosphates and selectivity identical to that of the wildtype receptor
    • 1 receptor tagged with green-fluorescent protein: high-affinity ligand recognition of adenosine diphosphates and triphosphates and selectivity identical to that of the wildtype receptor. Biochem Pharmacol 99:791-800.
    • (2000) Biochem Pharmacol , vol.99 , pp. 791-800
    • Vöhringer, C.1    Schäffer, R.2    Reiser, G.3
  • 30
    • 0030437695 scopus 로고    scopus 로고
    • Extracellular purine metabolism
    • Zimmermann H (1996) Extracellular purine metabolism. Drug Dev Res 39:337-352.
    • (1996) Drug Dev Res , vol.39 , pp. 337-352
    • Zimmermann, H.1
  • 31
    • 0033766981 scopus 로고    scopus 로고
    • Extracellular metabolism of ATP and other nucleotides
    • Zimmermann H (2000) Extracellular metabolism of ATP and other nucleotides. Naunyn-Schmiederberg's Arch Pharmacol 362:299-309.
    • (2000) Naunyn-Schmiederberg's Arch Pharmacol , vol.362 , pp. 299-309
    • Zimmermann, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.