Interplay of constitutively released nucleotides, nucleotide metabolism, and activity of P2Y receptors

Drug Development Research

Volumn 53, Issue 2-3, 2001, Pages 66-71

  Lazarowski, Eduardo R ^a   Boucher, Richard C ^a   Harden, T Kendall ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

ATP release; Nucleotide metabolism; P2Y receptors; UTP

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE PYROPHOSPHATASE; GUANOSINE TRIPHOSPHATE; INOSITOL PHOSPHATE; NUCLEOSIDE DIPHOSPHATE KINASE; NUCLEOTIDE; PHOSPHATE; PHOSPHORIC ACID; PURINE P2Y RECEPTOR; PYROPHOSPHATE; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE; URIDINE TRIPHOSPHATE;

ANIMAL CELL; BRONCHUS MUCOSA; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME ACTIVITY; EPITHELIUM CELL; GLIOMA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYDROLYSIS; NONHUMAN; NUCLEOTIDE METABOLISM; PROTEIN DETERMINATION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; PROTEIN TRANSPORT; RECEPTOR INTRINSIC ACTIVITY; STEADY STATE;

EID: 0034857737     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/ddr.1172     Document Type: Conference Paper

References (4)

1. Abraham EH, Okunieff P, Scala S, Vos P, Oosterveld MJS, Chen AY, Shrivastav B, Guidotti, G. 1997. Cystic fibrosis transmembrane conductance regulator and adenosine triphosphates. Science 275:1324-1325.
2. Boyer JL, Waldo GL, Harden TK. 1997. Molecular cloning and expression of an avian G protein-coupled P2Y receptor. Mol Pharmacol 52:928-934.
3. Grygorczyk R, Hanrahan JW 1997. CFTR-independent ATP release from epithelial cells triggered by mechanical stimuli. Am J Physiol 272:C1058-1066.
4. Grygorczyk R, Tabcharani JA, Hanrahan JW. 1996. CFTR channels expressed in CHO cells do not have detectable ATP conductance. J Membr Biol 151:139-148.