Characterization of the interaction between a novel convulsant agent, norbiphen, and GABAA and other ligand-gated ion channels

Neuropharmacology

Volumn 43, Issue 4, 2002, Pages 778-787

  Halliwell, R F ^a   Su, Jiping ^a   Demuro, A ^b   Martinez Torres, A ^b   Miledi, R ^b  

^a DURHAM UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Fluoroquinolones; GABA receptors; Norfloxacin biphenyl acetic acid hybrid; NSAIDs

Indexed keywords

(1,2,5,6 TETRAHYDROPYRIDIN 4 YL)METHYLPHOSPHINIC ACID; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID C RECEPTOR BLOCKING AGENT; BICUCULLINE; CONVULSANT AGENT; GLUTAMIC ACID; GLYCINE; LIGAND; N METHYL DEXTRO ASPARTIC ACID; NONSTEROID ANTIINFLAMMATORY AGENT; NORBIPHEN; QUINOLONE DERIVATIVE; RECEPTOR SUBUNIT; UNCLASSIFIED DRUG; ZINC CHLORIDE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHANNEL GATING; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; ELECTROPHYSIOLOGY; EMBRYO; HIPPOCAMPUS; IC 50; NONHUMAN; OOCYTE; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; CONVULSANTS; ELECTROPHYSIOLOGY; HIPPOCAMPUS; HUMANS; ION CHANNEL GATING; ION CHANNELS; LIGANDS; MEMBRANE POTENTIALS; NEURONS; NORFLOXACIN; OOCYTES; PATCH-CLAMP TECHNIQUES; PHENYLACETATES; PLASMIDS; RECEPTORS, GABA-A; RECOMBINANT PROTEINS; XENOPUS;

EID: 0036753702     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(02)00173-9     Document Type: Article

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