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Volumn 55, Issue 2, 1999, Pages 248-254

The α9 nicotinic acetylcholine receptor shares pharmacological properties with type A γ-aminobutyric acid, glycine, and type 3 serotonin receptors

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; ACETYLCHOLINE; BICUCULLINE; CYSTEINE; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; GLYCINE; GLYCINE RECEPTOR; GLYCINE RECEPTOR ANTAGONIST; LIGAND; NICOTINIC RECEPTOR; RECEPTOR BLOCKING AGENT; SEROTONIN 3 ANTAGONIST; SEROTONIN 3 RECEPTOR; STRYCHNINE; TROPISETRON; 1,2-BIS(2-AMINOPHENOXY)ETHANE-N,N,N',N'-TETRAACETIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; AMINO ACID RECEPTOR AFFECTING AGENT; BARIUM; CALCIUM; CHELATING AGENT; COMPLEMENTARY DNA; DRUG DERIVATIVE; EGTAZIC ACID; HYBRID PROTEIN; INDO 1 PENTAACETOXYMETHYL ESTER; INDO-1 PENTAACETOXYMETHYL ESTER; INDOLE DERIVATIVE; SEROTONIN; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR;

EID: 0032586945     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.55.2.248     Document Type: Article
Times cited : (92)

References (38)
  • 1
    • 0023240887 scopus 로고
    • Multiple mechanisms of antagonism of γ-aminobutyric acid (GABA) responses
    • Akaike N, Yakushiji T, Tokutomi N and Carpenter D (1987) Multiple mechanisms of antagonism of γ-aminobutyric acid (GABA) responses. Cell Mol Neurobiol 7:97-103.
    • (1987) Cell Mol Neurobiol , vol.7 , pp. 97-103
    • Akaike, N.1    Yakushiji, T.2    Tokutomi, N.3    Carpenter, D.4
  • 2
    • 0025856536 scopus 로고
    • Neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes have a pentameric quaternary structure
    • Anand R, Conroy W, Schoepfer R, Whiting P and Lindstrom J (1991) Neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes have a pentameric quaternary structure. J Biol Chem 266:11192-11198.
    • (1991) J Biol Chem , vol.266 , pp. 11192-11198
    • Anand, R.1    Conroy, W.2    Schoepfer, R.3    Whiting, P.4    Lindstrom, J.5
  • 3
    • 0020644119 scopus 로고
    • A transient calcium-dependent chloride current in the immature Xenopus oocyte
    • Barish M (1983) A transient calcium-dependent chloride current in the immature Xenopus oocyte. J Physiol 342:309-325.
    • (1983) J Physiol , vol.342 , pp. 309-325
    • Barish, M.1
  • 4
    • 0024496741 scopus 로고
    • Two calcium-activated chloride conductances in Xenopus laevis oocytes permeabilized with the ionophore A23187
    • Boton R, Dascal N, Gillo B and Lass Y (1989) Two calcium-activated chloride conductances in Xenopus laevis oocytes permeabilized with the ionophore A23187. J Physiol 408:511-534.
    • (1989) J Physiol , vol.408 , pp. 511-534
    • Boton, R.1    Dascal, N.2    Gillo, B.3    Lass, Y.4
  • 5
    • 0023447276 scopus 로고
    • Functional expression of two neuronal nicotinic acetylcholine receptors from cDNA clones identifies a gene family
    • Boulter J, Connolly J, Deneris E, Goldman D, Heinemann S and Patrick J (1987) Functional expression of two neuronal nicotinic acetylcholine receptors from cDNA clones identifies a gene family. Proc Natl Acad Sci USA 84:7763-7767.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 7763-7767
    • Boulter, J.1    Connolly, J.2    Deneris, E.3    Goldman, D.4    Heinemann, S.5    Patrick, J.6
  • 6
    • 0000491326 scopus 로고
    • The nicotinic acetylcholine receptor: Molecular architecture of a ligand-regulated ion channel
    • Changeux J, Giraudat J and Dennis M (1987) The nicotinic acetylcholine receptor: Molecular architecture of a ligand-regulated ion channel. Trends Pharmacol Sci 8:459-465.
    • (1987) Trends Pharmacol Sci , vol.8 , pp. 459-465
    • Changeux, J.1    Giraudat, J.2    Dennis, M.3
  • 7
    • 0025828670 scopus 로고
    • Pentameric structure and subunit stoichiometry of a neuronal nicotinic acetylcholine receptor
    • Cooper E, Couturier S and Ballivet M (1991) Pentameric structure and subunit stoichiometry of a neuronal nicotinic acetylcholine receptor. Nature (Lond) 350: 235-238.
    • (1991) Nature (Lond) , vol.350 , pp. 235-238
    • Cooper, E.1    Couturier, S.2    Ballivet, M.3
  • 8
    • 0025605864 scopus 로고
    • A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTX
    • Couturier S, Bertrand D, Matter J-M, Hernandez M-C, Bertrand S, Millar N, Valera S, Barkas T and Ballivet M (1990) A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTX. Neuron 5:847-856.
    • (1990) Neuron , vol.5 , pp. 847-856
    • Couturier, S.1    Bertrand, D.2    Matter, J.-M.3    Hernandez, M.-C.4    Bertrand, S.5    Millar, N.6    Valera, S.7    Barkas, T.8    Ballivet, M.9
  • 9
    • 0028171296 scopus 로고
    • Alpha9: An acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells
    • Elgoyhen AB, Johnson DS, Boulter J, Vetter DE and Heinemann S(1994) Alpha9: an acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells. Cell 79:705-715.
    • (1994) Cell , vol.79 , pp. 705-715
    • Elgoyhen, A.B.1    Johnson, D.S.2    Boulter, J.3    Vetter, D.E.4    Heinemann, S.5
  • 10
    • 0028214530 scopus 로고
    • In vitro characterization of a cholinergic receptor on outer hair cells
    • Erostegui C, Norris CH and Bobbin RP (1994) In vitro characterization of a cholinergic receptor on outer hair cells. Hearing Res 74:135-147.
    • (1994) Hearing Res , vol.74 , pp. 135-147
    • Erostegui, C.1    Norris, C.H.2    Bobbin, R.P.3
  • 11
    • 0026505159 scopus 로고
    • A novel cholinergic receptor mediates inhibition of chick cochlear hair cells
    • Fuchs PA and Murrow BW (1992) A novel cholinergic receptor mediates inhibition of chick cochlear hair cells. Proc R Soc Lond B Biol Sci 248:35-40.
    • (1992) Proc r Soc Lond b Biol Sci , vol.248 , pp. 35-40
    • Fuchs, P.A.1    Murrow, B.W.2
  • 12
    • 0025884565 scopus 로고
    • Functional architecture of the nicotinic acetylcholine receptor: From electric organ to brain
    • Galzi J-L, Revah F, Bessis A and Changuex JP (1991) Functional architecture of the nicotinic acetylcholine receptor: from electric organ to brain. Annu Rev Pharmacol 31:37-72.
    • (1991) Annu Rev Pharmacol , vol.31 , pp. 37-72
    • Galzi, J.-L.1    Revah, F.2    Bessis, A.3    Changuex, J.P.4
  • 13
    • 0028915971 scopus 로고
    • Effects of serotonergic agents on neuronal nicotinic acetylcholine receptors
    • García-Colunga J and Miledi R (1995) Effects of serotonergic agents on neuronal nicotinic acetylcholine receptors. Proc Natl Acad Sci USA 92:2919-2923.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 2919-2923
    • García-Colunga, J.1    Miledi, R.2
  • 14
    • 0028177088 scopus 로고
    • Homomers of α8 and α7 subunits of nicotinic receptors exhibit similar channel but contrasting binding site properties
    • Gerzanich V, Anand R and Lindstrom J (1994) Homomers of α8 and α7 subunits of nicotinic receptors exhibit similar channel but contrasting binding site properties. Mol Pharmacol 45:212-220.
    • (1994) Mol Pharmacol , vol.45 , pp. 212-220
    • Gerzanich, V.1    Anand, R.2    Lindstrom, J.3
  • 15
    • 0030569350 scopus 로고    scopus 로고
    • Expression of nicotinic acetylcholine receptor mRNA in the adult rat peripheral vestibular system
    • Hiel H, Elgoyhen A, Drescher D and Morley B (1996) Expression of nicotinic acetylcholine receptor mRNA in the adult rat peripheral vestibular system. Brain Res 738:347-352.
    • (1996) Brain Res , vol.738 , pp. 347-352
    • Hiel, H.1    Elgoyhen, A.2    Drescher, D.3    Morley, B.4
  • 16
    • 0025876633 scopus 로고
    • Direct measurement of the action of acetylcholine on isolated outer hair cells of the guinea pig cochlea
    • Housley GD and Ashmore JF (1991) Direct measurement of the action of acetylcholine on isolated outer hair cells of the guinea pig cochlea. Proc R Soc Lond B Biol Sci 244:161-167.
    • (1991) Proc R Soc Lond B Biol Sci , vol.244 , pp. 161-167
    • Housley, G.D.1    Ashmore, J.F.2
  • 17
    • 0028981913 scopus 로고
    • α-Conotoxin Im1 exhibits subtype-specific nicotinic acetylcholine receptor blockade: Preferential inhibition of homomeric α7 and α9 receptors
    • Johnson D, Martinez J, Elgoyhen A, Heinemann S and McIntosh J (1995) α-Conotoxin Im1 exhibits subtype-specific nicotinic acetylcholine receptor blockade: preferential inhibition of homomeric α7 and α9 receptors. Mol Pharmacol 48:194-199.
    • (1995) Mol Pharmacol , vol.48 , pp. 194-199
    • Johnson, D.1    Martinez, J.2    Elgoyhen, A.3    Heinemann, S.4    McIntosh, J.5
  • 18
    • 0029593370 scopus 로고
    • Toward a structural basis for the function of nicotinic acetylcholine receptors and their cousins
    • Karlin A and Akabas M (1995) Toward a structural basis for the function of nicotinic acetylcholine receptors and their cousins. Neuron 15:1231-1244.
    • (1995) Neuron , vol.15 , pp. 1231-1244
    • Karlin, A.1    Akabas, M.2
  • 19
    • 0028922693 scopus 로고
    • Molecular evolution of the nicotinic acetylcholine receptor: An example of multigene family in excitable cells
    • Le Novere N and Changeux J (1995) Molecular evolution of the nicotinic acetylcholine receptor: an example of multigene family in excitable cells. J Mol Evol 40:155-172.
    • (1995) J Mol Evol , vol.40 , pp. 155-172
    • Le Novere, N.1    Changeux, J.2
  • 20
    • 0028670240 scopus 로고
    • γ-Aminobutyric acid type A receptor antagonists picrotoxin and bicuculline alter acetylcholine channel kinetics in cultured embryonic rat skeletal muscle
    • Liu Q, Dunlap V and Barker J (1994) γ-Aminobutyric acid type A receptor antagonists picrotoxin and bicuculline alter acetylcholine channel kinetics in cultured embryonic rat skeletal muscle. Mol Pharmacol 46:1197-1203.
    • (1994) Mol Pharmacol , vol.46 , pp. 1197-1203
    • Liu, Q.1    Dunlap, V.2    Barker, J.3
  • 21
    • 0025997336 scopus 로고
    • Primary structure and functional expression of the 5HT3 receptor, a serotonin-gated ion channel
    • Maricq A, Peterson A, Brake A, Myers R and Julius D (1991) Primary structure and functional expression of the 5HT3 receptor, a serotonin-gated ion channel. Science (Washington DC) 254:432-436.
    • (1991) Science (Washington DC) , vol.254 , pp. 432-436
    • Maricq, A.1    Peterson, A.2    Brake, A.3    Myers, R.4    Julius, D.5
  • 23
    • 0028965629 scopus 로고
    • Physiological diversity of nicotinic acetylcholine receptors expressed by vertebrate neurons
    • McGehee D and Role L (1995) Physiological diversity of nicotinic acetylcholine receptors expressed by vertebrate neurons. Annu Rev Physiol 57:521-546.
    • (1995) Annu Rev Physiol , vol.57 , pp. 521-546
    • McGehee, D.1    Role, L.2
  • 24
    • 0031883931 scopus 로고    scopus 로고
    • Identification of the subunits of the nicotinic cholinergic receptors in the rat cochlea using RT-PCR and in situ hybridization
    • Morley B, Li H, Hiel H, Drescher D and Elgoyhen A (1998) Identification of the subunits of the nicotinic cholinergic receptors in the rat cochlea using RT-PCR and in situ hybridization. Mol Brain Res 53:78-87.
    • (1998) Mol Brain Res , vol.53 , pp. 78-87
    • Morley, B.1    Li, H.2    Hiel, H.3    Drescher, D.4    Elgoyhen, A.5
  • 25
    • 0019490688 scopus 로고
    • Snake alpha-toxin effects on cholinergic and noncholinergic responses of Aplysia californica neurons
    • Ono J and Salvaterra P (1981) Snake alpha-toxin effects on cholinergic and noncholinergic responses of Aplysia californica neurons. J Neurosci 1:259-270.
    • (1981) J Neurosci , vol.1 , pp. 259-270
    • Ono, J.1    Salvaterra, P.2
  • 26
    • 0028796049 scopus 로고
    • Evolutionary history of the ligand-gated ion-channel superfamily of receptors
    • Ortells M and Lunt G (1995) Evolutionary history of the ligand-gated ion-channel superfamily of receptors. Trends Neurol Sci 18:121-127.
    • (1995) Trends Neurol Sci , vol.18 , pp. 121-127
    • Ortells, M.1    Lunt, G.2
  • 27
    • 0029763194 scopus 로고    scopus 로고
    • Threonine-for-leucine mutation within domain M2 of the neuronal α7 nicotinic receptor converts 5-hydroxytryptamine from antagonist to agonist
    • Palma E, Miledi AM, Eusebi F and Miledi R (1996) Threonine-for-leucine mutation within domain M2 of the neuronal α7 nicotinic receptor converts 5-hydroxytryptamine from antagonist to agonist. Proc Natl Acad Sci USA 93:11231-11235.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 11231-11235
    • Palma, E.1    Miledi, A.M.2    Eusebi, F.3    Miledi, R.4
  • 28
    • 0027398069 scopus 로고
    • The diversity of neuronal nicotinic acetylcholine receptors
    • Sargent PB (1993) The diversity of neuronal nicotinic acetylcholine receptors. Annu Rev Neurosci 16:403-443.
    • (1993) Annu Rev Neurosci , vol.16 , pp. 403-443
    • Sargent, P.B.1
  • 29
    • 0026607904 scopus 로고
    • Agonist pharmacology of neonatal and adult glycine receptor α subunits: Identification of amino acid residues involved in taurine activation
    • Schmieden V, Kuhse J and Betz H (1992) Agonist pharmacology of neonatal and adult glycine receptor α subunits: identification of amino acid residues involved in taurine activation. EMBO (Eur Mol Biol Organ) J 11:2025-2032.
    • (1992) EMBO (Eur Mol Biol Organ) J , vol.11 , pp. 2025-2032
    • Schmieden, V.1    Kuhse, J.2    Betz, H.3
  • 30
    • 0002247473 scopus 로고    scopus 로고
    • Neurotransmitters and synaptic transmission
    • (Dallos P, Popper AN, Fay RR eds) Springer-Verlag, New York
    • Sewell W (1996) Neurotransmitters and synaptic transmission, in The cochlea (Dallos P, Popper AN, Fay RR eds) pp 503-533, Springer-Verlag, New York.
    • (1996) The Cochlea , pp. 503-533
    • Sewell, W.1
  • 31
    • 0026607902 scopus 로고
    • Point mutations affecting antagonist affinity and agonist dependent gating of GABAA receptor channels
    • Sigel E, Baur R, Kellenberger S and Malherbe P (1992) Point mutations affecting antagonist affinity and agonist dependent gating of GABAA receptor channels. EMBO (Eur Mol Biol Organ) J 11:2017-2023.
    • (1992) EMBO (Eur Mol Biol Organ) J , vol.11 , pp. 2017-2023
    • Sigel, E.1    Baur, R.2    Kellenberger, S.3    Malherbe, P.4
  • 33
    • 0026536645 scopus 로고
    • Antagonism of ligand-gated ion channel receptors: Two domains of the glycine receptor alpha subunit form the strychnine-binding site
    • Vandenberg R, French C, Barry P, Shin EJ and Schofield P (1992a) Antagonism of ligand-gated ion channel receptors: two domains of the glycine receptor alpha subunit form the strychnine-binding site. Proc Natl Acad Sci USA 89:1765-1769.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 1765-1769
    • Vandenberg, R.1    French, C.2    Barry, P.3    Shin, E.J.4    Schofield, P.5
  • 34
    • 0026787189 scopus 로고
    • Distinct agonist- and antagonist-binding sites on the glycine receptor
    • Vandenberg R, Handford C and Schofield P (1992b) Distinct agonist- and antagonist-binding sites on the glycine receptor. Neuron 9:491-496.
    • (1992) Neuron , vol.9 , pp. 491-496
    • Vandenberg, R.1    Handford, C.2    Schofield, P.3
  • 35
    • 0027169801 scopus 로고
    • The extracellular disulfide loop motif of the inhibitory glycine receptor does not form the agonist binding site
    • Vandenberg R, Rajendra S, French C, Barry P and Schofield P (1993) The extracellular disulfide loop motif of the inhibitory glycine receptor does not form the agonist binding site. Mol Pharmacol 44:198-203.
    • (1993) Mol Pharmacol , vol.44 , pp. 198-203
    • Vandenberg, R.1    Rajendra, S.2    French, C.3    Barry, P.4    Schofield, P.5
  • 36
    • 0025194255 scopus 로고
    • Effects of 5-HT3 receptor antagonists on 5-HT and nicotinic depolarizations in guinea-pig submucosal neurones
    • Vanner S and Suprenant A (1990) Effects of 5-HT3 receptor antagonists on 5-HT and nicotinic depolarizations in guinea-pig submucosal neurones. Br J Pharmacol 99:840-844.
    • (1990) Br J Pharmacol , vol.99 , pp. 840-844
    • Vanner, S.1    Suprenant, A.2
  • 37
    • 0027018868 scopus 로고
    • Pharmacological profiles of the GABA and acetylcholine receptors from the nematode, Ascaris suum
    • Walker R, Colquhoun L and Holden-Dye L (1992) Pharmacological profiles of the GABA and acetylcholine receptors from the nematode, Ascaris suum. Acta Biol Hungar 43:59-68.
    • (1992) Acta Biol Hungar , vol.43 , pp. 59-68
    • Walker, R.1    Colquhoun, L.2    Holden-Dye, L.3
  • 38
    • 0025855193 scopus 로고
    • Bicuculline blocks nicotinic acetylcholine responses in isolated intermediate lobe cells of the pig
    • Zhang Z and Feltz P (1991) Bicuculline blocks nicotinic acetylcholine responses in isolated intermediate lobe cells of the pig. Br J Pharmacol 102:19-22.
    • (1991) Br J Pharmacol , vol.102 , pp. 19-22
    • Zhang, Z.1    Feltz, P.2


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