메뉴 건너뛰기




Volumn 46, Issue 3, 2002, Pages 233-243

The influence of chain length and base sequence on the pharmacokinetic behavior of 99mTc-morpholinos in mice

Author keywords

Base sequence; Neoplasms, radionuclide imaging; Oligonucleotides; Pharmacokinetics; Technetium

Indexed keywords

CARCINOEMBRYONIC ANTIBODY; DNA; MORPHOLINE 15; MORPHOLINE 18; MORPHOLINE 25; MORPHOLINE DERIVATIVE; OLIGOMER; OLIGONUCLEOTIDE; TECHNETIUM 99M; UNCLASSIFIED DRUG;

EID: 0036750551     PISSN: 11243937     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (33)

References (19)
  • 1
    • 0030960680 scopus 로고    scopus 로고
    • Pharmacokinetics considerations in the development of oligomers as radiopharmaceuticals
    • Hnatowich DJ, Pharmacokinetics considerations in the development of oligomers as radiopharmaceuticals. Q J Nucl Med 1997; 41:91-100.
    • (1997) Q J Nucl Med , vol.41 , pp. 91-100
    • Hnatowich, D.J.1
  • 2
    • 0029926891 scopus 로고    scopus 로고
    • Comparative properties of a technetium-99m-labeled single-stranded natural DNA and a phosphorothioate derivative in vitro and in vivo in mice
    • Hnatowich DJ, Mardirossian G, Fogarasi M, Sano T, Smith CL, Cantor CR et al. Comparative properties of a technetium-99m-labeled single-stranded natural DNA and a phosphorothioate derivative in vitro and in vivo in mice. Pharm Exp Ther 1996;276:326-34.
    • (1996) Pharm Exp Ther , vol.276 , pp. 326-334
    • Hnatowich, D.J.1    Mardirossian, G.2    Fogarasi, M.3    Sano, T.4    Smith, C.L.5    Cantor, C.R.6
  • 3
    • 0030943935 scopus 로고    scopus 로고
    • Comparative pharmacokinetics, tissue distribution, and tumor accumulation of phosphorothioiate, phosphorodithioiate, and methylphosphonate oligonucleotides in nude mice
    • DeLong RK, Nolting A, Fisher M, Chen Q, Wickstrom E, Kligshteyn M et al. Comparative pharmacokinetics, tissue distribution, and tumor accumulation of phosphorothioiate, phosphorodithioiate, and methylphosphonate oligonucleotides in nude mice. Antisense Nucleic Acid Drug Dev 1997;7:71-7.
    • (1997) Antisense Nucleic Acid Drug Dev , vol.7 , pp. 71-77
    • DeLong, R.K.1    Nolting, A.2    Fisher, M.3    Chen, Q.4    Wickstrom, E.5    Kligshteyn, M.6
  • 4
    • 0030970532 scopus 로고    scopus 로고
    • In vivo hybridization of technetium-99m-labeled peptide nucleic acid (PNA)
    • Mardirossian G, Lei K, Rusckowski M, Chang F, Qu T, Egholm M et al. In vivo hybridization of technetium-99m-labeled peptide nucleic acid (PNA). J Nucl Med 1997;38:907-13.
    • (1997) J Nucl Med , vol.38 , pp. 907-913
    • Mardirossian, G.1    Lei, K.2    Rusckowski, M.3    Chang, F.4    Qu, T.5    Egholm, M.6
  • 6
    • 0000780274 scopus 로고    scopus 로고
    • Phasphorodiamidate morpholino oligomers
    • In: Crooke STT, editor; New York: Marcel Dekker, Inc.
    • Iversen P. Phasphorodiamidate morpholino oligomers. In: Crooke STT, editor. Antisense drug technology. New York: Marcel Dekker, Inc.; 2001. p. 375-89.
    • (2001) Antisense Drug Technology , pp. 375-389
    • Iversen, P.1
  • 8
    • 0032906375 scopus 로고    scopus 로고
    • Antisense and nuclear medicine
    • Hnatowich DJ. Antisense and nuclear medicine. J Nucl Med 1999;40:693-703.
    • (1999) J Nucl Med , vol.40 , pp. 693-703
    • Hnatowich, D.J.1
  • 10
    • 0030772278 scopus 로고    scopus 로고
    • Pattern and kinetics of cytokine production following administration of phosphorothioate oligonucleotides in mice
    • Zhao Q, Temasamani J, Zhou RZ, Agrawal S. Pattern and kinetics of cytokine production following administration of phosphorothioate oligonucleotides in mice. Antisense Nucleic Acid Drug 1997;7:495-502.
    • (1997) Antisense Nucleic Acid Drug , vol.7 , pp. 495-502
    • Zhao, Q.1    Temasamani, J.2    Zhou, R.Z.3    Agrawal, S.4
  • 11
    • 0032780440 scopus 로고    scopus 로고
    • Effect of oligomer length and base substitutions on the cytotoxic activity and specific nuclear protein recognition of GTn oligonucleotides in human leukemic CCRF-CEM cell line
    • Morasutti C, Dapas B, Scaggiante B, Paroni G, Xodo L, Quadrifoglio F. Effect of oligomer length and base substitutions on the cytotoxic activity and specific nuclear protein recognition of GTn oligonucleotides in human leukemic CCRF-CEM cell line. Nucleosides Nucleotides 1999;18:1711-6.
    • (1999) Nucleosides Nucleotides , vol.18 , pp. 1711-1716
    • Morasutti, C.1    Dapas, B.2    Scaggiante, B.3    Paroni, G.4    Xodo, L.5    Quadrifoglio, F.6
  • 12
    • 0035834454 scopus 로고    scopus 로고
    • Defining the peptide nucleic acid (PNA) length requirement for PNA binding-induced transcription and gene expression
    • Wang G, Jiang K, Balczon R, Xu X. Defining the peptide nucleic acid (PNA) length requirement for PNA binding-induced transcription and gene expression. J Mol Biol 2001;313:933-40.
    • (2001) J Mol Biol , vol.313 , pp. 933-940
    • Wang, G.1    Jiang, K.2    Balczon, R.3    Xu, X.4
  • 14
    • 0037079676 scopus 로고    scopus 로고
    • The reactivity of phosphodiester bond within linear single-stranded oligoribonucleotides is strongly dependent on base sequence
    • Kaukinen U, Lyytikainen S, Mikkola S, Lonnberg H. The reactivity of phosphodiester bond within linear single-stranded oligoribonucleotides is strongly dependent on base sequence. Nucl Acids Res 2002;30:468-74.
    • (2002) Nucl Acids Res , vol.30 , pp. 468-474
    • Kaukinen, U.1    Lyytikainen, S.2    Mikkola, S.3    Lonnberg, H.4
  • 16
    • 0034814422 scopus 로고    scopus 로고
    • Pretargeting with amplification using polymeric peptide nucleic acid (PNA)
    • Wang Y, Chang F, Zhang Y, Liu N, Liu G, Gupta S et al. Pretargeting with amplification using polymeric peptide nucleic acid (PNA). Bioconj Chem 2001;12:807-16.
    • (2001) Bioconj Chem , vol.12 , pp. 807-816
    • Wang, Y.1    Chang, F.2    Zhang, Y.3    Liu, N.4    Liu, G.5    Gupta, S.6
  • 19
    • 0031472380 scopus 로고    scopus 로고
    • Pretargeting using peptide nucleic acid (PNA)
    • Rusckowski M, Qu T, Chang F, Hnatowich DJ. Pretargeting using peptide nucleic acid (PNA). Cancer 1997;80:2699-705.
    • (1997) Cancer , vol.80 , pp. 2699-2705
    • Rusckowski, M.1    Qu, T.2    Chang, F.3    Hnatowich, D.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.