Stem cells and lineage plasticity: The challenge to existing paradigms

Immunological Reviews

Volumn 187, Issue , 2002, Pages 5-8

  Dorshkind, Kenneth ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE; BLOOD CELL; BONE MARROW CELL; CELL ASSAY; CELL MATURATION; DUCHENNE MUSCULAR DYSTROPHY; HEMATOPOIESIS; LYMPHOID CELL; PLASTICITY; PRECURSOR; PRIORITY JOURNAL; REVIEW; STEM CELL; T LYMPHOCYTE;

ANIMALS; CELL DIFFERENTIATION; CELL LINEAGE; FETUS; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HUMANS; LYMPHOCYTES; PLURIPOTENT STEM CELLS;

EID: 0036750373     PISSN: 01052896     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-065X.2002.18701.x     Document Type: Review

References (22)

1. Kondo M, Weissman I, Akashi K. Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 1997;91:661-672.
2. Akashi K, Traver D, Miyamoto T, Weissman IL. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature 2000;404:193-197.
3. Gussoni E, et al. Dystrophin expression in the mdx mouse restored by stem cell transplantation. Nature 1999;401:390-394.
4. Jackson KA, et al. Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells. J Clin Invest 2001;107:1395-1402.
5. Lagasse E, et al. Purified hematopoietic stem cells can differentiate into hepatocytes in vivo. Nat Med 2000;6:1229-1234.
6. Krause DS, et al. Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell. Cell 2001;105:369-377.
7. Anderson DJ, Gage FH, Weissman IL. Can stem cells cross lineage boundaries? Nat Med 2001;4:393-395.
8. Morrison SJ. Stem cell potential: can anything make anything. Current Biol 2001;11:R7-R9.
9. Hochedlinger K, Jaenisch R. Monoclonal mice generated by nuclear transfer from mature B and T donor cells. Nature 2002;415:1035-1038.
10. Dorshkind K. Multilineage development from adult bone marrow cells. Nature Immunol 2002;3:311-313.
11. Orkin SH, Zon LI. Hematopoiesis and stem cells: plasticity versus developmental heterogeneity. Nat Immunol 2002;3:323-328.
12. Terada N, et al. Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion. Nature 2002;416:542-545.
13. Ying Q-L, Nichols J, Evans EP, Smith AG. Changing potency by spontaneous fusion. Nature 2002;416:545-548.
14. Pui JC, et al. Notch 1 expression in early lymphopoiesis influences B versus T lineage determination. Immunity 1999;11:299-308.
15. Radtke F, et al. Deficient T cell fate specification in mice with an induced inactivation of Notch 1. Immunity 1999;10:547-558.
16. Kawamata S, Du C, Li K, Lavau C. Notch 1 perturbation of hemopoiesis involves non-cell-autonomous modifications. J Immunol 2002;168:1738-1745.
17. Nutt SL, Heavey B, Rolink AG, Busslinger M. Commitment to the B-lymphoid lineage depends on the transcription factor Pax5. Nature 1999;401:556-562.
18. Kawamoto H, Ohmura K, Katsura Y. Direct evidence for the commitment of hematopoietic stem cells to T, B, and myeloid lineages in murine fetal liver. Int Immunol 1997;9:1011-1019.
19. Mebius RE, et al. The fetal liver counterpart of adult common lymphoid progenitors gives rise to all lymphoid lineages, CD45+CD4+CD3- cells, as well as macrophages. J Immunol 2001;166:6593-6601.
20. Kawamoto H, Ohmura K, Fujimoto S, Katsura Y. Emergence of T cell progenitors without B cell or myeloid differentiation potential at then earliest stage of hematopoiesis in the murine fetal liver. J Immunol 1999;162:2725-2731.
21. Lacaud G, Carlsson L, Keller G. Identification of a fetal hematopoietic precursors with B cell, T cell, and macrophage potential. Immunity 1998;9:827-838.
22. Graf T. Differentiation plasticity of hematopoietic cells. Blood 2002;99:3089-3101.