-
1
-
-
0035136962
-
The changing face of chemotherapy in colorectal cancer
-
Waters J, Cunningham D. The changing face of chemotherapy in colorectal cancer. Br J Cancer 2001; 84: 1-7.
-
(2001)
Br. J. Cancer
, vol.84
, pp. 1-7
-
-
Waters, J.1
Cunningham, D.2
-
2
-
-
0032585197
-
Randomised trial of irinotecan versus fluorouracil by continuous infusion after fluorouracil failure in patients with metastatic colorectal cancer
-
Rougier P, Van Cutsem E, Bajetta E et al. Randomised trial of irinotecan versus fluorouracil by continuous infusion after fluorouracil failure in patients with metastatic colorectal cancer. Lancet 1998; 352: 1407-1412.
-
(1998)
Lancet
, vol.352
, pp. 1407-1412
-
-
Rougier, P.1
Van Cutsem, E.2
Bajetta, E.3
-
3
-
-
0032585232
-
Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer
-
Cunningham D, Pryhonen S, James RD et al. Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer. Lancet 1998; 352: 1413-1418.
-
(1998)
Lancet
, vol.352
, pp. 1413-1418
-
-
Cunningham, D.1
Pryhonen, S.2
James, R.D.3
-
4
-
-
0031014627
-
Phase II study of irinotecan in the treatment of advanced colorectal cancer in chemotherapy-naive patients patients pretreated with fluorouracil-based chemotherapy
-
Rougier P, Bugat R, Douillard JY et al. Phase II study of irinotecan in the treatment of advanced colorectal cancer in chemotherapy-naive patients and patients pretreated with fluorouracil-based chemotherapy. J Clin Oncol 1997; 15: 251-260.
-
(1997)
J. Clin. Oncol
, vol.15
, pp. 251-260
-
-
Rougier, P.1
Bugat, R.2
Douillard, J.Y.3
-
5
-
-
0034727063
-
Irinotecan plus fluorouracil leucovorin for metastatic colorectal cancer
-
Irinotecan Study Group
-
Saltz LB, Cox JV, Blanke C et al. Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. Irinotecan Study Group. N Engl J Med 2000; 343: 905-914.
-
(2000)
N. Engl. J. Med
, vol.343
, pp. 905-914
-
-
Saltz, L.B.1
Cox, J.V.2
Blanke, C.3
-
6
-
-
0034712536
-
Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: A multicentre randomised trial
-
Douillard JY, Cunningham D, Roth AD et al. Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial. Lancet 2000; 355: 1041-1047.
-
(2000)
Lancet
, vol.355
, pp. 1041-1047
-
-
Douillard, J.Y.1
Cunningham, D.2
Roth, A.D.3
-
7
-
-
0027426408
-
Dihydropyrimidine dehydrogenase activity in human peripheral blood mononuclear cells and liver: Population characteristics, newly identified deficient patients, and clinical implication in 5-fluorouracil chemotherapy
-
Lu Z, Zhang R, Diasio RB. Dihydropyrimidine dehydrogenase activity in human peripheral blood mononuclear cells and liver: population characteristics, newly identified deficient patients, and clinical implication in 5-fluorouracil chemotherapy. Cancer Res 1993; 53: 5433-5438.
-
(1993)
Cancer Res
, vol.53
, pp. 5433-5438
-
-
Lu, Z.1
Zhang, R.2
Diasio, R.B.3
-
8
-
-
0034901306
-
Lethal outcome of a patient with a complete dihydropyrimidine dehydrogenase (DPD) deficiency after administration of 5-fluorouracil: Frequency of the common IVS14 + 1G>A mutation causing DPD deficiency
-
Van Kuilenburg AB, Muller EW, Haasjes J et al. Lethal outcome of a patient with a complete dihydropyrimidine dehydrogenase (DPD) deficiency after administration of 5-fluorouracil: frequency of the common IVS14 + 1G>A mutation causing DPD deficiency. Clin Cancer Res 2001; 7: 1149-1153.
-
(2001)
Clin. Cancer Res
, vol.7
, pp. 1149-1153
-
-
Van Kuilenburg, A.B.1
Muller, E.W.2
Haasjes, J.3
-
9
-
-
0028280275
-
Fluorouracil cardiotoxicity
-
Anand AJ. Fluorouracil cardiotoxicity. Ann Pharmacother 1994; 28: 374-378.
-
(1994)
Ann. Pharmacother
, vol.28
, pp. 374-378
-
-
Anand, A.J.1
-
10
-
-
0027472160
-
The syndrome of 5-fluorouracil cardiotoxicity. An elusive cardiopathy
-
Robben NC, Pippas AW, Moore JO. The syndrome of 5-fluorouracil cardiotoxicity. An elusive cardiopathy. Cancer 1993; 71: 493-509.
-
(1993)
Cancer
, vol.71
, pp. 493-509
-
-
Robben, N.C.1
Pippas, A.W.2
Moore, J.O.3
-
11
-
-
0031888857
-
Mature results from three large controlled studies with raltitrexed ('Tomudex')
-
Cunningham D. Mature results from three large controlled studies with raltitrexed ('Tomudex'). Br J Cancer 1998; 77 (Suppl 2): 15-21.
-
(1998)
Br. J. Cancer
, vol.77
, Issue.SUPPL. 2
, pp. 15-21
-
-
Cunningham, D.1
-
12
-
-
0035016457
-
Safe administration of irinotecan, oxaliplatin and raltitrexed in a DPD-deficient patient with metastatic colon cancer
-
Volk J, Reinke F, van Kuilenburg AB et al. Safe administration of irinotecan, oxaliplatin and raltitrexed in a DPD-deficient patient with metastatic colon cancer. Ann Oncol 2001; 12: 569-571.
-
(2001)
Ann. Oncol
, vol.12
, pp. 569-571
-
-
Volk, J.1
Reinke, F.2
van Kuilenburg, A.B.3
-
13
-
-
0031888945
-
Raltitrexed (Tomudex): An alternative drug for patients with colorectal cancer 5-fluorouracil associated cardiotoxicity
-
Kohne CH, Thuss-Patience P, Friedrich M et al. Raltitrexed (Tomudex): an alternative drug for patients with colorectal cancer and 5-fluorouracil associated cardiotoxicity. Br J Cancer 1998; 77: 973-937.
-
(1998)
Br. J. Cancer
, vol.77
, pp. 937-973
-
-
Kohne, C.H.1
Thuss-Patience, P.2
Friedrich, M.3
-
14
-
-
0031949701
-
Schedule-dependent synergism between raltitrexed and irinotecan in human colon cancer cells in vitro
-
Aschele C, Baldo C, Sobrero AF et al. Schedule-dependent synergism between raltitrexed and irinotecan in human colon cancer cells in vitro. Clin Cancer Res 1998; 4: 1323-1330.
-
(1998)
Clin. Cancer Res
, vol.4
, pp. 1323-1330
-
-
Aschele, C.1
Baldo, C.2
Sobrero, A.F.3
-
15
-
-
0034086719
-
Phase I study of irinotecan raltitrexed in patients with advanced gastrointestinal tract adeno-carcinoma
-
Ford HE, Cunningham D, Ross PJ et al. Phase I study of irinotecan and raltitrexed in patients with advanced gastrointestinal tract adeno-carcinoma. Br J Cancer 2000; 83: 146-152.
-
(2000)
Br. J. Cancer
, vol.83
, pp. 146-152
-
-
Ford, H.E.1
Cunningham, D.2
Ross, P.J.3
-
16
-
-
0024536437
-
Optimal two-stage designs for phase II clinical trials
-
Simon R. Optimal two-stage designs for phase II clinical trials. Control Clin Trials 1989; 10: 1-10.
-
(1989)
Control Clin. Trials
, vol.10
, pp. 1-10
-
-
Simon, R.1
-
17
-
-
0023595233
-
Applications of dose intensity to problems in chemotherapy of breast colorectal cancer
-
Hryniuk WM, Figueredo A, Goodyear M. Applications of dose intensity to problems in chemotherapy of breast and colorectal cancer. Semin Oncol 1987; 14 (Suppl 4): 3-11.
-
(1987)
Semin. Oncol
, vol.14
, Issue.SUPPL. 4
, pp. 3-11
-
-
Hryniuk, W.M.1
Figueredo, A.2
Goodyear, M.3
-
18
-
-
0022124023
-
Confidence limits for probability of response in multistage phase II clinical trial
-
Atkinson EN, Brown BW. Confidence limits for probability of response in multistage phase II clinical trial. Biometrics 1985; 41: 741-744.
-
(1985)
Biometrics
, vol.41
, pp. 741-744
-
-
Atkinson, E.N.1
Brown, B.W.2
-
19
-
-
0033874892
-
Leucovorin fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer
-
De Gramont A, Figer A, Seymour M et al. Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. J Clin Oncol 2000; 18: 2938-2947.
-
(2000)
J. Clin. Oncol
, vol.18
, pp. 2938-2947
-
-
De Gramont, A.1
Figer, A.2
Seymour, M.3
-
20
-
-
0035849938
-
Recommendation for caution with irinotecan fluorouracil leucovorin for colorectal cancer
-
Sargent DJ, Niedzwiecki D, O'Connell MJ, Schilsky R. Recommendation for caution with irinotecan, fluorouracil, and leucovorin for colorectal cancer. N Engl J Med 2001; 345: 144-146.
-
(2001)
N. Engl. J. Med
, vol.345
, pp. 144-146
-
-
Sargent, D.J.1
Niedzwiecki, D.2
O'Connell, M.J.3
Schilsky, R.4
-
21
-
-
0035884212
-
Mortality associated with irinotecan plus bolus fluorouracil/leucovorin: Summary findings of an independent panel
-
Rothenberg ML, Meropol NJ, Poplin EA et al. Mortality associated with irinotecan plus bolus fluorouracil/leucovorin: summary findings of an independent panel. J Clin Oncol 2001; 19: 3801-3807.
-
(2001)
J. Clin. Oncol
, vol.19
, pp. 3801-3807
-
-
Rothenberg, M.L.1
Meropol, N.J.2
Poplin, E.A.3
|