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Volumn 83, Issue 2, 2000, Pages 146-152

Phase I study of irinotecan and raltitrexed in patients with advanced gastrointestinal tract adenocarcinoma

Author keywords

Drug combination; Irinotecan; Pharmacokinetics; Phase I; Raltitrexed

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; IRINOTECAN; RALTITREXED;

EID: 0034086719     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1054/bjoc.2000.1192     Document Type: Article
Times cited : (24)

References (25)
  • 2
    • 0028854897 scopus 로고
    • Phase I and pharmacologic studies of the camptothecin analog irinotecan administered every 3 weeks in cancer patients
    • Abigerges D, Chabot GG, Armand JP, Herait P, Gouyette A and Gandia D (1995) Phase I and pharmacologic studies of the camptothecin analog irinotecan administered every 3 weeks in cancer patients. J Clin Oncol 13: 210-221
    • (1995) J Clin Oncol , vol.13 , pp. 210-221
    • Abigerges, D.1    Chabot, G.G.2    Armand, J.P.3    Herait, P.4    Gouyette, A.5    Gandia, D.6
  • 3
    • 0031963985 scopus 로고    scopus 로고
    • Comparison of plasma and tissue levels of ZD1694 (Tomudex), a highly polyglutamable quinazoline thymidylate synthase inhibitor in preclinical models
    • Aherne GW, Ward E, Lawrence N, Dobinson D, Clarke SJ, Musgrove H, Sutcliffe F, Stephens T and Jackman AL (1998) Comparison of plasma and tissue levels of ZD1694 (Tomudex), a highly polyglutamable quinazoline thymidylate synthase inhibitor in preclinical models. Br J Cancer 77: 221-226
    • (1998) Br J Cancer , vol.77 , pp. 221-226
    • Aherne, G.W.1    Ward, E.2    Lawrence, N.3    Dobinson, D.4    Clarke, S.J.5    Musgrove, H.6    Sutcliffe, F.7    Stephens, T.8    Jackman, A.L.9
  • 4
    • 0029929434 scopus 로고    scopus 로고
    • CPT-11: Clinical experience in phase 1 studies
    • Armand JP (1996) CPT-11: clinical experience in phase 1 studies. Semin Oncol 23 (suppl. 3): 27-33
    • (1996) Semin Oncol , vol.23 , Issue.SUPPL. 3 , pp. 27-33
    • Armand, J.P.1
  • 9
  • 13
    • 0025997350 scopus 로고
    • ICI D1694, a quinazoline antifolate thymidylate synthase inhibitor that is a potent inhibitor of L1210 tumor cell growth in vitro and in vivo: A new agent for clinical study
    • Jackman AL, Taylor GA, Gibson W, Kimbell R, Brown M, Calvert AH, Judson IR and Hughes LR (1991) ICI D1694, a quinazoline antifolate thymidylate synthase inhibitor that is a potent inhibitor of L1210 tumor cell growth in vitro and in vivo: a new agent for clinical study. Cancer Res 51: 5579-5586
    • (1991) Cancer Res , vol.51 , pp. 5579-5586
    • Jackman, A.L.1    Taylor, G.A.2    Gibson, W.3    Kimbell, R.4    Brown, M.5    Calvert, A.H.6    Judson, I.R.7    Hughes, L.R.8
  • 15
    • 33845382806 scopus 로고
    • Nonparametric estimation from incomplete observations
    • Kaplan EL and Meier P (1958) Nonparametric estimation from incomplete observations. J Am Stat Assoc 53: 457-481
    • (1958) J Am Stat Assoc , vol.53 , pp. 457-481
    • Kaplan, E.L.1    Meier, P.2
  • 17
    • 0026762968 scopus 로고
    • Expectancy or primary chemotherapy in patients with advanced asymptomatic colon cancer: A randomized trial
    • Nordic Gastrointestinal Tumor Adjuvant Therapy Group (1992) Expectancy or primary chemotherapy in patients with advanced asymptomatic colon cancer: a randomized trial. J Clin Oncol 10: 904-911
    • (1992) J Clin Oncol , vol.10 , pp. 904-911
  • 18
    • 0032956544 scopus 로고    scopus 로고
    • Antiangiogenic effects of camptothecin analogs 9-amino-10(S)-camptothecin, topotecan and CPT-11 studied in the mouse cornea model
    • O'Leary JJ, Shapiro RL, Ren CJ, Chuang N, Cohen HW and Potemsil M (1999) Antiangiogenic effects of camptothecin analogs 9-amino-10(S)-camptothecin, topotecan and CPT-11 studied in the mouse cornea model. Clinical Cancer Research 5(1): 181-187
    • (1999) Clinical Cancer Research , vol.5 , Issue.1 , pp. 181-187
    • O'Leary, J.J.1    Shapiro, R.L.2    Ren, C.J.3    Chuang, N.4    Cohen, H.W.5    Potemsil, M.6
  • 21
    • 0031014627 scopus 로고    scopus 로고
    • Phase II study of irinotecan in the treatment of advanced colorectal cancer in chemotherapynaïve patients and patients pretreated with fluorouracil based chemotherapy
    • Rougier P, Bugat R, Douillard JY, Culine S, Suc E, Brunet P, Becouarn Y, Ychou M, Many M and Extra JM (1997) Phase II study of irinotecan in the treatment of advanced colorectal cancer in chemotherapynaïve patients and patients pretreated with fluorouracil based chemotherapy. J Clin Oncol 15: 251-260
    • (1997) J Clin Oncol , vol.15 , pp. 251-260
    • Rougier, P.1    Bugat, R.2    Douillard, J.Y.3    Culine, S.4    Suc, E.5    Brunet, P.6    Becouarn, Y.7    Ychou, M.8    Many, M.9    Extra, J.M.10
  • 23
    • 0000389059 scopus 로고    scopus 로고
    • Weekly irinotecan (CPT-11), leucovorin (LV) and fluorouracil (FU) is superior to daily x5 LV/FU in patients with previously untreated metastatic colorectal cancer
    • abstract 898
    • Saltz LB, Locker PK, Pirotta N, Elfring GL and Miller LL (1999) Weekly irinotecan (CPT-11), leucovorin (LV) and fluorouracil (FU) is superior to daily x5 LV/FU in patients with previously untreated metastatic colorectal cancer. Proc Am Soc Clin Oncol 18: 233a (abstract 898)
    • (1999) Proc Am Soc Clin Oncol , vol.18
    • Saltz, L.B.1    Locker, P.K.2    Pirotta, N.3    Elfring, G.L.4    Miller, L.L.5
  • 24
    • 0028221421 scopus 로고
    • Activity of CPT-11 (irinotecan hydrochloride), a topoisomerase I inhibitor, against human tumor colony-forming units
    • Shimada Y, Rothenberg M, Hilsenbeck SG, Burris HA, Degen D and Von Hoff D (1994) Activity of CPT-11 (irinotecan hydrochloride), a topoisomerase I inhibitor, against human tumor colony-forming units. Anticancer Drugs 5: 202-206
    • (1994) Anticancer Drugs , vol.5 , pp. 202-206
    • Shimada, Y.1    Rothenberg, M.2    Hilsenbeck, S.G.3    Burris, H.A.4    Degen, D.5    Von Hoff, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.