Adrenomedullin inhibits doxorubicin-induced cultured rat cardiac myocyte apoptosis via a cAMP-dependent mechanism

Endocrinology

Volumn 143, Issue 9, 2002, Pages 3515-3521

  Tokudome, Takeshi ^a   Horio, Takeshi ^a   Yoshihara, Fumiki ^a   Suga, Shin Ichi ^a   Kawano, Yuhei ^a   Kohno, Masakazu ^b   Kangawa, Kenji ^a  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^b KAGAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

8 BROMO CYCLIC AMP; ACETYLCYSTEINE; ADRENOMEDULLIN; CALCITONIN GENE RELATED PEPTIDE RECEPTOR; CALCITONIN GENE RELATED PEPTIDE[8-37]; CASPASE 3; CATALASE; CYCLIC AMP; DNA FRAGMENT; DOXORUBICIN; LACTATE DEHYDROGENASE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOCRINE EFFECT; CELL CULTURE; CELL DAMAGE; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; ENZYME ACTIVATION; GENE EXPRESSION; HEART DISEASE; HEART MUSCLE CELL; KNOCKOUT MOUSE; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ACETYLCYSTEINE; ADRENOMEDULLIN; ANIMALS; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; APOPTOSIS; CALCITONIN GENE-RELATED PEPTIDE; CARDIOTONIC AGENTS; CATALASE; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DNA FRAGMENTATION; DOXORUBICIN; ENZYME INHIBITORS; FREE RADICAL SCAVENGERS; HUMANS; ISOQUINOLINES; L-LACTATE DEHYDROGENASE; MYOCARDIUM; PEPTIDE FRAGMENTS; PEPTIDES; RATS; RATS, WISTAR; RECEPTORS, CALCITONIN GENE-RELATED PEPTIDE; RECOMBINANT PROTEINS; SULFONAMIDES;

EID: 0036721441     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2002-220233     Document Type: Article

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