Effects of gender and age on the association of apolipoprotein E ε4 with bone mineral density, bone turnover and the risk of fractures in older people

Osteoporosis International

Volumn 13, Issue 9, 2002, Pages 701-709

  Pluijm, S M F ^a   Dik, M G ^a   Jonker, C ^a   Deeg, D J H ^a,a   Kamp, G J Van ^a   Lips, P ^a,a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

ApoE; Bone markers; Bone mineral density; Fractures; Ultrasound; Vertebral deformities

Indexed keywords

APOLIPOPROTEIN E; APOLIPOPROTEIN E EPSILON4; DEOXYPYRIDINOLINE; OSTEOCALCIN; UNCLASSIFIED DRUG;

ADULT; AGE; AGED; AGING; ARTICLE; BONE DENSITY; BONE MINERAL; BONE TURNOVER; ECHOGRAPHY; FEMALE; FOLLOW UP; FRACTURE; GENDER; GENETIC RISK; HIP; HUMAN; LONGITUDINAL STUDY; LUMBAR SPINE; MAJOR CLINICAL STUDY; MALE; NETHERLANDS; PRIORITY JOURNAL; QUANTITATIVE DIAGNOSIS; RISK ASSESSMENT; URINALYSIS; VERTEBRA MALFORMATION;

AGED; AGING; ALLELES; AMINO ACIDS; APOLIPOPROTEIN E4; APOLIPOPROTEINS E; BIOLOGICAL MARKERS; BONE DENSITY; BONE REMODELING; CALCANEUS; FEMALE; FRACTURES, BONE; HUMANS; LONGITUDINAL STUDIES; MALE; MULTIVARIATE ANALYSIS; OSTEOCALCIN; RISK FACTORS; SEX CHARACTERISTICS; SPINAL FRACTURES;

EID: 0036714871     PISSN: 0937941X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001980200096     Document Type: Article

References (42)

1. Genetic factors in determining bone mass
2. Genetic determinants of bone mass in adults. A twin study
3. Bone mass, lean mass, and fat mass: Same genes or same environments?
4. Prediction of bone density from vitamin D receptor alleles
5. Early postmenopausal bone loss is associated with PvuII estrogen receptor gene polymorphism in Finnish women: Effect of hormone replacement therapy
6. Relation of alleles of the collagen type 1alpha1 gene to bone density and the risk of osteoporotic fractures in postmenopausal women
7. Bone fracture history and prospective bone fracture risk of hemodialysis patients are related to apolipoprotein E genotype
8. Association of bone mineral density with apolipoprotein E phenotype
9. Apolipoprotein E polymorphism: A new genetic marker of hip fracture risk: The Study of Osteoporotic Fractures
10. Apolipoprotein E gene polymorphism and bone loss: Estrogen status modifies the influence of apolipoprotein E on bone loss
11. ApoE 4 and hip fracture risk in a community-based study of older adults
12. Genetic mutations affecting human lipoproteins, their receptors, and their enzymes
13. Does apolipoprotein E genotype relate to BMD and bone markers in postmenopausal women?
14. Dietary vitamin K intakes are associated with hip fracture but not with bone mineral density in elderly men and women
15. Osteoporosis and apolipoprotein E genotype in older adults: The Rancho Bernardo Study
16. Genetic factors and osteoporotic fractures in elderly people: Prospective 25 year follow up of a nation wide cohort of elderly Finnish twins
17. Procedures and results of the field work
18. A rapid micromethod for apolipoprotein E phenotyping directly in serum
19. Assessment of body composition with use of dual energy X-ray absorptiometry: Evaluation and comparison with other methods
20. Assessment of the composition of major body regions by dual energy X-ray absorptiometry (DEXA), with special reference to limb muscle mass
21. Ultrasound measurements in the calcaneus: Precision and its relation with bone mineral density of the heel, hip and lumbar spine
22. The prevalence of vertebral deformity in European men and women: The European Vertebral Osteoporosis Study
23. Vertebral fracture assessment using a semiquantitative technique
24. Consequences of vertebral deformities in older men and women
25. 'Mini-mental state': A practical method for grading the cognitive state of patients for the clinician
26. The prevalence of selected physical activities and their relation with coronary heart disease risk factors in elderly men: The Zutphen Study, 1985
27. A physical activity questionnaire for the elderly
28. A short physical performance battery assessing lower extremity function: Association with self-reported disability and prediction of mortality and nursing home admission
29. Uncritical use of bone mineral density in absorptiometry may lead to size-related artefacts in the identification of bone mineral determinants
30. Consequences of childhood-onset growth hormone deficiency for adult bone mass
31. Is the apoE4 alelle an independent predictor of coronary events?
32. Apolipoprotein E4 and coronary heart disease in middle-aged men who smoke: A prospective study
33. Apolipoprotein E polymorphism predicts death from coronary heart disease in a longitudinal study of elderly Finnish men
34. An ecological study of association between coronary heart disease mortality rates in men and the relative frequencies of common allelic variations in the gene coding for apolipoprotein E
35. Genotypes with the apolipoprotein ε4 allele are predictors of coronary heart disease mortality in a longitudinal study of elderly Finnish men
36. Transport of vitamin K to bone in humans
37. Serum undercarboxylated osteocalcin is a marker of the risk of hip fracture: A three year follow-up study
38. Apolipoprotein E polymorphism in The Netherlands and its effect on plasma lipid and apolipoprotein levels
39. Effects of apolipoprotein E polymorphism on plasma lipoprotein(a) levels
40. Role of lipids in osteoporosis