Serum undercarboxylated osteocalcin is a marker of the risk of hip fracture: A three year follow-up study

Bone

Volumn 18, Issue 5, 1996, Pages 487-488

  Szulc, P ^a   Chapuy, M C ^a   Meunier, P J ^a   Delmas, Pierre D ^a  

^a EDOUARD HERRIOT HOSPITAL   (France)

Author keywords

Gammacarboxyglutamic acid; Hip fracture; Osteocalcin; Osteoporosis; Vitamin D; Vitamin K

Indexed keywords

ALKALINE PHOSPHATASE; OSTEOCALCIN; PARATHYROID HORMONE;

AGED; ALKALINE PHOSPHATASE BLOOD LEVEL; ARTICLE; BLOOD LEVEL; CARBOXYLATION; CONTROLLED STUDY; FEMALE; FOLLOW UP; HIP FRACTURE; HUMAN; MAJOR CLINICAL STUDY; NUTRITIONAL DEFICIENCY; REGRESSION ANALYSIS; RISK;

EID: 0029879059     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/8756-3282(96)00037-3     Document Type: Article

References (8)

1. Brown, J., Delmas, P. D., Malaval, L., Edouard, C., Chapuy, M. C., and Meunier, P. J. Serum bone Gla-protein: A specific marker for bone formation in postmenopausal osteoporosis. Lancet 1:1091-1093; 1984.
2. 3 and calcium to prevent hip fracture in elderly women. N Engl J Med 327:1637-1642; 1992.
3. Hodges, S. J., Vergnaud, P., Akesson, K., Obrant, K., and Delmas, P. D., Circulating levels of vitamin K1 and K2 are decreased in elderly women with hip fracture. J Bone Miner Res 8:1241-1245; 1993.
4. Knapen, M. H. J., Hamulyak, K., and Vermeer, C. The effect of vitamin K supplementation on circulating osteocalcin (bone G1a protein) and urinary calcium excretion. Ann Intern Med 111:1001-1005; 1989.
5. Merle, B. and Delmas, P. D. Normal carboxylation of circulating osteocalcin (bone Gla-protein) in Paget's disease of bone. Bone Miner 11:237-245; 1990.
6. Plantalech, L., Guillaumont, M., Vergnaud, P., Leclercq, M., and Delmas, P. D. Impaired carboxylation of serum osteocalcin in elderly women. J Bone Miner Res 6:1211-1216; 1991.
7. Szulc, P., Chapuy, M. C., Meunier, P. J., and Delmas, P. D. Serum undercarboxylated osteocalcin is a marker of the risk of hip fracture in elderly women. J Clin Invest 91:1769-1774; 1993.
8. Szulc, P., Arlot, M., Chapuy, M. C., Duboeuf, F., Meunier, P. J., and Delmas, P. D. Serum undercarboxylated osteocalcin correlated with the hip Bone Mineral Density in elderly women. J. Bone Miner Res 9:1591-1595; 1994.