Molecular organization of amyloid protofilament-like assembly of betabellin 15D: Helical array of β-sandwiches

Biophysical Journal

Volumn 83, Issue 3, 2002, Pages 1716-1727

  Inouye, Hideyo ^a,b,c   Bond, Jeremy E ^a,b   Deverin, Sean P ^a,b   Lim, Amareth ^a,b   Costello, Catherine E ^a,b   Kirschner, Daniel A ^a,b  

^a BOSTON COLLEGE   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Global Prior Art Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID; BETABELLIN; PREALBUMIN; UNCLASSIFIED DRUG; ACETONITRILE; ACETONITRILE DERIVATIVE; BETABELLIN 15; PEPTIDE; PROTEIN; RECOMBINANT PROTEIN;

ARTICLE; BETA SHEET; DISULFIDE BOND; HYDROGEN BOND; MATHEMATICAL ANALYSIS; MOLECULAR INTERACTION; MOLECULAR MODEL; PROTEIN ASSEMBLY; PROTEIN FOLDING; PROTEIN STRUCTURE; ULTRASTRUCTURE; X RAY DIFFRACTION; AMINO ACID SEQUENCE; BIOPHYSICS; CHEMICAL STRUCTURE; CHEMISTRY; DIMERIZATION; MOLECULAR GENETICS; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; PROTEIN SYNTHESIS; RADIATION SCATTERING; STATISTICAL MODEL;

ACETONITRILES; AMINO ACID SEQUENCE; AMYLOID; BIOPHYSICS; DIMERIZATION; MODELS, MOLECULAR; MODELS, STATISTICAL; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN BIOSYNTHESIS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEINS; RECOMBINANT PROTEINS; SCATTERING, RADIATION; X-RAY DIFFRACTION;

EID: 0036708477     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(02)73939-8     Document Type: Article

References (42)

1. Synchrotron X-ray studies suggest that the core of the transthyretin amyloid fibril is a continuous β-sheet helix
2. A rotational offset model for two-stranded F-actin
3. The relationship between Bragg reflections and disorder in crystalline polymers
4. The structure of synthetic polypeptides. I. The transform of atoms on a helix
5. The Fourier transform of a coiled-coil
6. The packing of a-helices: Simple coiled-coils
7. The Fourier transform of actin and other helical systems with cumulative random angular disorder
8. The splitting of layer lines in X-ray fibre diagrams of helical structures: Application to tobacco mosaic virus
9. Morphology and antibody recognition of synthetic β-amyloid peptides
10. Fibril formation by primate, rodent and Dutch-haemorrhagic analogues of Alzheimer amyloid β-protein
11. Knowledge-based protein secondary structure assignment
12. "Cross-β" conformation in proteins
13. SWISS-MODEL and the Swiss-PdbViewer: An environment for comparative protein modeling
14. Protein modelling for all
15. X-ray scattering from a discrete helix with cumulative angular and translational disorders
16. Structural changes in a hydrophobic domain of the prion protein induced by hydration and by Ala → Val and Pro → Leu substitutions
17. Analysis of X-ray diffraction patterns from amyloid of biopsied vitreous humor and kidney of transthyretin (TTR) Met30 familial amyloidotic polyneuropathy (FAP) patients: Axially arrayed TTR monomers constitute the protofilament
18. Structure of β-crystallite assemblies formed by Alzheimer β-amyloid protein analogues: Analysis by X-ray diffraction
19. Membrane structure in isolated and intact myelins
20. Folding and function of the myelin proteins from primary sequence data
21. X-ray diffraction analysis of scrapie prions: Intermediate and folded structures in a peptide containing two putative α-helices
22. Polypeptide chain folding in the hydrophobic core of hamster scrapie prion: Analysis by X-ray diffraction
23. Dictionary of protein secondary structure: Pattern recognition of hydrogen-bonded and geometrical features
24. Diffraction by helical structures
25. MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures
26. Engineering of betabellin-15D: A 64 residue β sheet protein that forms long narrow multimeric fibrils
27. Engineering of betabellin 15D: Copper(II)-induced folding of a fibrillar β-sandwich protein
28. Betabellins 15D and 16D, de novo designed β-sandwich proteins that have amyloidogenic properties
29. A family of double helices of alternating poly(gamma-benzyl-D-L-glutamate), a stereochemical model for gramicidin A
30. Structural analysis of Alzheimer's β(1-40) amyloid: Protofilament assembly of tubular fibrils
31. Solvent content of protein crystals
32. XtalView: A visual protein crystallographic software system for X11/Xview
33. Is counterion delocalization responsible for collapse in RNA folding?
34. X-ray diffraction of scrapie prion rods and PrP peptides
35. Small permanent magnet for fields up to 2.6 T
36. Compound helical configurations of polypeptide chains: Structure of proteins of the alpha-keratin type
37. The de novo design of protein structures
38. High-resolution electron microscopic analysis of the amyloid fibril
39. Common core structure of amyloid fibrils by synchrotron X-ray diffraction
40. A theory of X-ray scattering by disordered polymer crystals
41. Free energies for refolding of the common β turn into the inverse-common β turn: Simulation of the role of D/L chirality
42. Free energies for folding and refolding of four types of β turns: Simulation of the role of D/L chirality