Structural changes in a hydrophobic domain of the prion protein induced by hydration and by Ala → Val and Pro → Leu substitutions

Journal of Molecular Biology

Volumn 300, Issue 5, 2000, Pages 1283-1296

  Inouye, Hideyo ^a   Bond, Jeremy ^a   Baldwin, Michael A ^b   Ball, Haydn L ^b   Prusiner, Stanley B ^b   Kirschner, Daniel A ^a  

^a BOSTON COLLEGE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Amyloidogenic peptide; Gerstmann Straussler Scheinker; Prion; X ray diffraction; pleated sheet

Indexed keywords

PRION PROTEIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; GENE MUTATION; HYDRATION; HYDROPHOBICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN FOLDING; PROTEIN STRUCTURE; X RAY DIFFRACTION;

EID: 0034725542     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2000.3926     Document Type: Article

References (40)

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