Effects of uncoupling protein 3 gene -55 C→T variant on lipid metabolism, body fat, its distribution and non-insulin-dependent diabetes mellitus in Chinese

Chinese Journal of Medical Genetics

Volumn 19, Issue 4, 2002, Pages 317-321

  Shen, Hailian ^a   Xiang, Kunsan ^a   Jia, Weiping ^a  

^a Shanghai Sixth Hospital   (China)

Author keywords

Body fat; Non insulin dependent diabetes mellitus; Uncoupling protein 3 gene

Indexed keywords

CHOLESTEROL; DISEASES; GLUCOSE; INSULIN; LIPIDS; METABOLISM; PROTEINS; REGRESSION ANALYSIS;

POLYMORPHISM;

GENETIC ENGINEERING;

CYTOSINE; MANGANESE; THYMINE; UNCOUPLING PROTEIN 3;

ADULT; AGED; ARTICLE; BODY DISTRIBUTION; BODY FAT; CAUCASIAN; CHINESE; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOTE; HUMAN; INDIAN; LIPID METABOLISM; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

ADIPOSE TISSUE; ADULT; AGED; ALLELES; BODY CONSTITUTION; BODY MASS INDEX; CARRIER PROTEINS; CHINA; CHOLESTEROL; CHOLESTEROL, HDL; CHOLESTEROL, LDL; DIABETES MELLITUS, TYPE 2; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; ION CHANNELS; LIPID METABOLISM; MALE; MIDDLE AGED; MITOCHONDRIAL PROTEINS; POINT MUTATION; REGRESSION ANALYSIS; TRIGLYCERIDES;

EID: 0036683854     PISSN: 10039406     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

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2. Towards a molecular understanding of adaptive thermogenesis
3. Human uncoupling proteins and obesity
4. Uncoupling protein 2 and 3 messenger ribonucleic acids in adipose tissue and skeletal muscle of healthy males: Variability, factors affecting expression and relation to measures of metabolic rate
5. Characterization of novel UCP5/BMCP1 isoforms and differential regulation of UCP4 and UCP5 expression through dietary or temperature manipulation
6. A genetic variation in the 5′ flanking region of the UCP3 gene is associated with body mass index in humans in interaction with physical activity
7. Skeletal muscle uncoupling protein 3 expression is a determinant of energy expenditure in Pima Indians
8. A novel polymorphism in the proximal UCP3 promoter region: Effect on skeletal muscle UCP3 mRNA expression and obesity in male non-diabetic Pima Indians
9. An uncoupling protein 3 gene polymophism associated with a lower risk of developing type I diabetes and with atherogenic lipid profile in a French cohort
10. Uncoupling protein 3 is reduced in skeletal muscle of NIDDM patients
11. Uncoupling protein 3 content is decreased in skeletal muscle of patients with type 2 diabetes