Suppression of synaptotagmin II restrains phorbolester-induced downregulation of protein kinase Cα by diverting the kinase from a degradative pathway to the recycling endocytic compartment

Journal of Cell Science

Volumn 115, Issue 15, 2002, Pages 3083-3092

  Peng, Ze ^a   Grimberg, Elena ^a   Sagi Eisenberg, Ronit ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

Endosome; Mast cells; Protein kinase C; Synaptotagmin; TPA

Indexed keywords

COMPLEMENTARY DNA; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C ALPHA; SYNAPTOTAGMIN; SYNAPTOTAGMIN II; UNCLASSIFIED DRUG; CYSTEINE PROTEINASE; ENZYME INHIBITOR; MULTIENZYME COMPLEX; NERVE PROTEIN; PHORBOL ESTER; PROTEASOME; PROTEIN KINASE C; SYT2 PROTEIN, RAT;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CELL COMPARTMENTALIZATION; CELL MEMBRANE; CONTROLLED STUDY; CYTOSOL; DNA TRANSFECTION; DOWN REGULATION; ENDOCYTOSIS; ENDOSOME; ENZYME DEGRADATION; ENZYME REPRESSION; HALF LIFE TIME; MAST CELL LEUKEMIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; RAT; RECYCLING; SECRETORY GRANULE; SIGNAL TRANSDUCTION; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENETICS; MAST CELL; METABOLISM; NUCLEIC ACID PROBE; PHYSIOLOGY; PROTEIN TRANSPORT; SECRETORY VESICLE;

ANIMALIA;

ANIMALS; ANTISENSE ELEMENTS (GENETICS); CELL COMPARTMENTATION; CELL MEMBRANE; CYSTEINE ENDOPEPTIDASES; CYTOSOL; DOWN-REGULATION; ENDOCYTOSIS; ENDOSOMES; ENZYME INHIBITORS; MAST CELLS; MULTIENZYME COMPLEXES; NERVE TISSUE PROTEINS; PHORBOL ESTERS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN KINASE C; PROTEIN KINASE C-ALPHA; PROTEIN TRANSPORT; RATS; SECRETORY VESICLES; SIGNAL TRANSDUCTION; SYNAPTOTAGMIN II; TUMOR CELLS, CULTURED;

EID: 0036676874     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.115.15.3083     Document Type: Article

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