Remobilization does not fully restore immobilization induced articular cartilage atrophy

Clinical Orthopaedics and Related Research

Volumn 362, Issue , 1999, Pages 218-229

  Haapala, Jussi ^a,b,e   Arokoski, Jari P A ^a   Hyttinen, Mika M ^b   Lammi, Mikko ^b   Tammi, Markku ^b   Kovanen, Vuokko ^c   Helminen, Heikki J ^b   Kiviranta, Ilkka ^d  

^a KUOPIO UNIVERSITY HOSPITAL   (Finland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

^c UNIVERSITY OF JYVÄSKYLÄ   (Finland)

^d JYVÄSKYLÄ CENTRAL HOSPITAL   (Finland)

^e PÄIJÄT HÄME CENTRAL HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSAMINOGLYCAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICULAR CARTILAGE; AUTORADIOGRAPHY; CARTILAGE DEGENERATION; CONFERENCE PAPER; CONTROLLED STUDY; CROSS LINKING; DOG; FEMALE; FEMUR CONDYLE; HISTOCHEMISTRY; IMMOBILIZATION; MICROSPECTROPHOTOMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEOGLYCAN SYNTHESIS; TIBIA;

EID: 0032943355     PISSN: 0009921X     EISSN: 15281132     Source Type: Journal    
DOI: 10.1097/00003086-199905000-00031     Document Type: Conference Paper

References (39)

1. Adams M, Matyas J, Dingqiu H, Dourado G: Expression of proteoglycans and collagen in the hypertrophic phase of experimental osteoarthritis. J Rheumatol 22:94-97, 1995.
2. Arokoski JP, Hyttinen MM, Lapveteläinen T, et al: Decreased birefringence of the superficial zone collagen network in the canine knee (stifle) articular cartilage after long distance running training, detected by quantitative polarized light microscopy. Ann Rheum Dis 55:253-264, 1996.
3. Behrens F, Kraft E, Oegema TJ: Biochemical changes in articular cartilage after joint immobilization by casting or external fixation. J Orthop Res 7:335-343, 1989.
4. Benninghoff A: Form und Bau der Gelenkknorpel in ihren Beziehungen zur Funktion. Erste Mitteilung: Die modellierenden und formerhaltenden Faktoren des Knorpelreliefs. Gesamte Anatomie Abt 1 76:43-63, 1925.
5. Black D, Duncan A, Robins S: Quantitative analysis of the pyridinium crosslinks of collagen in urine using ion-paired reversed-phase high-performance liquid chromatography. Anal Biochem 169:197-203, 1988.
6. Buckwalter J, Mankin H: Articular cartilage: Degeneration and osteoarthrosis, repair, regeneration, and transplantation. J Bone Joint Surg 79A:612-632, 1997.
7. Caterson B, Lowther DA: Changes in the metabolism of the proteoglycans from sheep articular cartilage in response to mechanical stress. Biochim Biophys Acta 540:412-422, 1978.
8. Eyre DR, Koob TJ, Van Ness KP: Quantitation of hydroxy/pyridinium crosslinks in collagen by high-performance liquid chromatography. Anal Biochem 137:380-388, 1984.
9. Finsterbush A, Friedman B: Reversibility of joint changes produced by immobilization in rabbits. Clin Orthop 111:290-298, 1975.
10. Heikkinen L, Panula H, Lyyra T, et al: Electromechanical film sensor device for dynamic force recording from canine limbs. Scand J Lab Anim Sci 2:85-92, 1997.
11. Helminen HJ, Säämänen A-M, Jurvelin J, et al: Kuormituksen vaikutus nivelrustoon. (in Finnish). Duodecim 108:1097-1107, 1992.
12. Jortikka M, Inkinen R, Tammi M, et al: Immobilization causes longlasting matrix changes both in the immobilized and contralateral joint cartilage. Ann Rheum Dis 56:255-261, 1997.
13. Jurvelin J, Kiviranta I, Tammi M, Helminen HJ: Softening of canine articular cartilage after immobilization of the knee joint. Clin Orthop 207:246-252, 1986.
14. Király K, Hyttinen MM, Lapveteläinen T, et al: Application of selected cationic dyes for the semiquantitative estimation of glycosaminoglycans in histological sections of articular cartilage by microspectrophotometry. Histochem J 28:577-590, 1996.
15. Kiviranta I: Joint Loading Influences on the Articular Cartilage of Young Dogs. Quantitative Histochemical Studies on Matrix Carbohydrates. PhD Thesis. Kuopio, Finland, University of Kuopio 1987.
16. Kiviranta I, Jurvelin J, Tammi M, Säämänen A-M, Helminen HJ: Microspectrophotometric quantitation of glycosaminoglycans in articular cartilage sections stained with safranin O. Histochemistry 82:249-255, 1985.
17. Kiviranta I, Tammi M, Arokoski J, et al: Effects of Mechanical Loading and Immobilization on the Articular Cartilage. In Järvinen M (ed). Bailliere's Clinical Orthopaedics. London, Bailliere-Tindall 109-122, 1997.
18. Kiviranta I, Tammi M, Jurvelin J, et al: Articular cartilage thickness and glycosaminoglycan distribution in the canine knee joint after strenuous running exercise. Clin Orthop 283:302-308, 1992.
19. Kiviranta I, Tammi M, Jurvelin J, et al: Articular cartilage thickness and glycosaminoglycan distribution in the young canine knee joint after remobilization of the immobilized limb. J Orthop Res 12:161-167, 1994.
20. Kiviranta I, Tammi M, Jurvelin J, Helminen HJ: Topographical variation of glycosaminoglycan content and cartilage thickness in canine knee (stifle) joint cartilage. Application of the microspectrophotometric method. J Anat 150:265-276, 1987.
21. Muir H, Carney S: Pathological and Biochemical Changes in Cartilage and Other Tissues of the Canine Knee Joint Instability. In Helminen HJ, Kiviranta I, Säämänen AM, et al (eds). Joint Loading. Biology and Health of Articular Cartilage, Bristol, Wright 47-63, 1986.
22. National Institutes of Health: Institute of Laboratory Animal Resources, National Research Council (1985) Guide for Care and Use of Laboratory Animals. NIH publication no 78-23. Bethesda, US Government Printing Office 1985.
23. Orford CR, Gardner DL, O'Connor P: Ultrastructural changes in dog femoral condylar cartilage following anterior cruciate ligament section. J Anat 137:653-663, 1983.
24. Palmoski M, Perricone E, Brandt KD: Development and reversal of a proteoglycan aggregation defect in normal canine knee cartilage after immobilization. Arthritis Rheum 22:508-517, 1979.
25. Palmoski MJ, Brandt KD: Running inhibits the reversal of atrophic changes in canine knee cartilage after removal of a leg cast. Arthritis Rheum 24:1329-1337, 1981.
26. Palmoski MJ, Colyer RA, Brandt KD: Joint motion in the absence of normal loading does not maintain normal articular cartilage. Arthritis Rheum 23:325-334, 1980.
27. Palokangas H, Kovanen V, Duncan R, Robins SP: Age related changes in the concentration of hydroxypyridinium crosslinks in functionally different skeletal muscles. Matrix 12:291-296, 1992.
28. Parkkinen JJ, Paukkonen K, Pesonen E, et al: Quantitation of autoradiographic grains in different zones of articular cartilage with image analyzer. Histochemistry 93:241-245, 1990.
29. Pelletier J-P, Martel-Pelletier J: Cartilage degradation by neutral proteoglycanases in experimental osteoarthritis. Arthritis Rheum 28:1393-1401, 1985.
30. Pelletier JP, Martel-Pelletier J, Malemud CJ: Canine osteoarthritis: Effects of endogenous neutral metalloproteoglycanases on articular cartilage proteoglycans. J Orthop Res 6:379-388, 1988.
31. Sandy JD: Extracellular Metabolism of Aggrecan. In Kuettner KE, Schleyerbach R, Peyron JG, Hascall VC (eds). Articular Cartilage and Osteoarthritis. New York, Raven Press 21-33, 1992.
32. Sandy JD, Adams ME, Billingham MEJ, Plaas A, Muir H: In-vivo and in-vitro stimulation of chondrocyte biosynthetic activity in early experimental osteoarthritis. Arthritis Rheum 27:388-397, 1984.
33. Säämänen A-M, Kiviranta I, Jurvelin J, Helminen HJ, Tammi M: Proteoglycan and collagen alterations in canine knee articular cartilage following 20 km daily running exercise for 15 weeks. Connect Tissue Res 30:191-201, 1994.
34. Säämänen A-M, Tammi M, Kiviranta I, Jurvelin J, Helminen HJ: Maturation of proteoglycan matrix in articular cartilage under increased and decreased joint loading. A study in young rabbits. Connect Tissue Res 16:163-175, 1987.
35. Tammi M, Paukkonen K, Kiviranta I, et al: Joint Loading Induced Alterations in Articular Cartilage. In Helminen HJ, Kiviranta I, Säämänen AM, et al (eds). Joint Loading. Biology and Health of Articular Structures, Bristol, Wright 64-88, 1987.
36. Tammi M, Säämänen A-M, Jauhiainen A, et al: Proteoglycan alterations in rabbit knee articular cartilage following physical exercise and immobilization. Connect Tissue Res 11:45-55, 1983.
37. Teerlink T, Tavenier P, Netelenbos JC: Selective determination of hydroxyproline in urine by high-performance liquid chromatography using precolumn derivatization. Clin Chim Acta 183:309-316, 1989.
38. Venn G, Billingham MEJ, Hardingham TE: Increased proteoglycan synthesis in cartilage in experimental canine osteoarthritis does not reflect a permanent change in chondrocyte phenotype. Arthritis Rheum 38:525-531, 1995.
39. Weibel E: Estimation of Basic Stereological Parameters. In Weibel E (ed). Stereological Methods. New York, Academy Press 55-104, 1980.