Immunomodulatory effect of antidepressants

Current Opinion in Pharmacology

Volumn 2, Issue 4, 2002, Pages 428-432

  Szelényi, Judith ^a   Selmeczy, Zsolt ^a  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; ALPHA 2 ADRENERGIC RECEPTOR; ANTIDEPRESSANT AGENT; BETA 2 ADRENERGIC RECEPTOR; BRAIN MONOAMINE; CATECHOLAMINE; CYTOKINE; INTERLEUKIN 10; MONOAMINE; NEUROTRANSMITTER; NORADRENALIN; SEROTONIN; SEROTONIN AGONIST; TRICYCLIC ANTIDEPRESSANT AGENT; BIOGENIC AMINE; IMMUNOLOGICAL ADJUVANT;

ARTICLE; CONTROLLED STUDY; DEPRESSION; DRUG EFFECT; DRUG EFFICACY; IMMUNOMODULATION; MENTAL DISEASE; MONOAMINE RELEASE; MONOAMINERGIC SYSTEM; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; ANIMAL; HUMAN; IMMUNOLOGY; METABOLISM; REVIEW;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIDEPRESSIVE AGENTS; BIOGENIC MONOAMINES; DEPRESSION; HUMANS;

EID: 0036667389     PISSN: 14714892     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1471-4892(02)00173-X     Document Type: Review

References (61)

1. The catecholamine hypothesis of affective disorders: A review of supporting evidence
2. The comparative pharmacology of new antidepressants
3. The macrophage theory of depression
4. The immune system, depression and the action of antidepressants
5. Presynaptic modulation of release of noradrenaline from the sympathetic nerve terminals in the rat spleen
6. 2-adrenoreceptors on plasma levels of tumour necrosis factor-α, interleukin-6 and corticosterone induced by bacterial lipopolysaccharide in mice
7. The sympathetic nerve - An integrative interface between two supersystems: The brain and the immune system
8. Receptor-mediated local fine-tuning by noradrenergic innervation of neuroendocrine and immune systems
9. Sympathetic activation triggers systemic interleukin-10 release in immunodepression induced by brain injury
10. Catecholamines trigger IL-10 release in acute systemic stress reaction by direct stimulation of its promoter/enhancer activity in monocytic cells
11. Noradrenergic regulation of inflammatory gene expression in brain
12. Noradrenergic inhibition of TNF upregulation in hemorrhagic shock
13. Modulation of hematopoiesis via α1-adrenergic receptors on bone marrow cells
14. Neonatal sympathetic denervation alters the development of in vitro spleen cell proliferation and differentiation
15. Role of high-affinity receptors and membrane transporters in nonsynaptic communication and drug action in the central nervous system
16. Immunoregulation mediated by the sympathetic nervous system, II
17. Neurochemical, electrophysiological and immunocytochemical evidence for a noradrenergic link between the sympathetic nervous system and thymocytes
18. Regulation of tumor necrosis factor production by adrenaline and β-adrenergic agonists
19. Noradrenaline inhibits lipopolysaccharide-induced tumor necrosis factor and interleukin 6 production in human whole blood
20. 2- and β-adrenoceptors in mice
21. Modulation of lipopolysaccharide-induced tumor necrosis factor-α production by selective α- and β-adrenergic drugs in mice
22. The effect of norepinephrine on endotoxin-mediated macrophage activation
23. Catecholamine-induced leukocytosis: Early observations, current research, and future directions
24. Central nervous system influences on lymphocyte migration
25. Cytokines and the central nervous system
26. Extracellular NE level is one of the key-regulators of the cytokine balance: Study with NET-KO mouse and tricyclic antidepressant treatment
27. Dopamine suppresses IL-12 p40 production by lipopolysaccharide-stimulated macrophages via a β-adrenoceptor-mediated mechanism./
28. Effect of serotonin (5-HT) and other monoamines on murine macrophages: Modulation of interferon-γ induced phagocytosis
29. Dopamine increases interleukin 6 release and inhibits tumor necrosis factor release from rat adrenal zona glomerulosa cells in vitro
30. Role of serotonin in the immune system and in neuroimmune interactions
31. Involvement of central vs. peripheral mechanisms in mediating sympathoadrenal activation in endotoxic rats
32. Interleukin-1 increases norepinephrine turnover in the spleen and lung in rats
33. An interleukin-1β-induced noradrenaline release in the spleen is mediated by brain corticotropin-releasing factor: An in vivo microdialysis study in conscious rats
34. Neural-immune interactions in health and disease
35. Cytokines and acute neurodegeneration
36. Circulating interleukin-6 mediates the febrile response to localised inflammation in rats
37. Febrile response to tissue inflammation involves both peripheral and brain IL-1 and TNF-α in the rat
38. Neuroimmune interactions: The role of cytokines
39. Cytokine-cytokine interactions and the brain
40. Glucocorticoid receptors in major depression: Relevance to pathophysiology and treatment
41. Interferon-γ plus lipopolysaccharide induction of delayed neuronal apoptosis in rat hippocampus
42. Interleukin 1 in the brain: Biology, pathology and therapeutic target
43. Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors
44. Depression, stress and immunological activation: The role of cytokines in depressive disorders
45. The effects of psychological stress on humans: Increased production of pro-inflammatory cytokines and a Th1-like response in stress-induced anxiety
46. Changes in the immune system in depression and dementia: Causal or co-incidental effects?
47. Regulation of nitric oxide synthase messenger RNA expression in the rat hippocampus by glucocorticoids
48. Cortical spreading depression induces proinflammatory cytokine gene expression in the rat brain
49. Cytokines and depression: Fortuitous or causative association?
50. Illness, cytokines, and depression
51. Negative immunoregulatory effects of antidepressants: Inhibition of interferon-γ and stimulation of interleukin-10 secretion
52. The effect of repeated amitriptyline and desipramine administration on cytokine release in C57BL/6 mice
53. Effects of antidepressant drugs on the behavioral and physiological responses to lipopolysaccharide (LPS) in rodents
54. The antidepressant and antiinflammatory effects of rolipram in the central nervous system
55. Expression of the cAMP response element binding protein (CREB) in hippocampus produces an antidepressant effect
56. Type II (glucocorticoid) receptors mediate fast-feedback inhibition of the hypothalamic-pituitary-adrenal axis in man
57. 2-adrenergic receptor sensitivity
58. Dopamine uptake through the norepinephrine transporter in brain regions with low levels of the dopamine transporter: Evidence from knock-out mouse lines
59. Effects of serotonin and serotonergic agonists and antagonists on the production of interferon-γ and interleukin-10
60. Methylenedioxymethamphetamine-induced suppression of interleukin-1β and tumour necrosis factor-α is not mediated by serotonin
61. Effects of chronic antidepressant treatments on 5-HT and NA transporters in rat brain: An autoradiographic study