Differential localization of IL-2- and -15 receptor chains in membrane rafts of human T cells

Journal of Leukocyte Biology

Volumn 72, Issue 1, 2002, Pages 199-206

  Goebel, Jens ^a,b   Forrest, Kathy ^a   Morford, Lorri ^a   Roszman, Thomas L ^a  

^a UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Cytokine receptors; Signal transduction; T lymphocytes

Indexed keywords

GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; INTERLEUKIN 15 RECEPTOR; INTERLEUKIN 2 RECEPTOR; LIPID; METHYL BETA CYCLODEXTRIN; PHYTOHEMAGGLUTININ; PROTEIN P56; UNCLASSIFIED DRUG;

ARTICLE; BETA CHAIN; CELL FRACTIONATION; CENTRIFUGATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LIPID RAFT; LYMPHOCYTE ACTIVATION; LYMPHOCYTE MEMBRANE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; T LYMPHOCYTE; WESTERN BLOTTING;

BETA-CYCLODEXTRINS; CELLS, CULTURED; CYCLODEXTRINS; G(M1) GANGLIOSIDE; HUMANS; INTERLEUKIN-2; INTERLEUKIN-2 RECEPTOR BETA SUBUNIT; LYMPHOCYTE ACTIVATION; MEMBRANE MICRODOMAINS; PROTEIN SUBUNITS; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-15; RECEPTORS, INTERLEUKIN-2; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 0036658748     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Viola, A., Schroeder, S., Sakakibra, Y., Lanzavecchia, A. (1999) T lymphocyte costimulation mediated by reorganization of membrane microdomains. Science 283, 680-682.
2. Bourguignon, L. Y. W., Tokuyasu, K. T., Singer, S. J. (1978) The capping of lymphocytes and other cells, studied by an improved method for immunofluorescence staining of frozen sections. J. Cell. Physiol. 95, 239-258.
3. Kammer, G. M., Smith, J. A., Mitchell, R. (1988) Capping of human T cell specific determinants: kinetics of capping and R re-expression and regulation by the cytoskeleton. J. Immunol. 130, 38-44.
4. Bourguignon, L. Y. W., Jy, W., Majercik, M. H., Bourguignon, G. H. (1988) Lymphocyte activation and capping of hormone Rs. J. Cell. Biochem. 37, 131-150.
5. Hoessli, D. C., Poincelet, M., Runger-Brändle, E. (1990) Isolation of high-affinity murine IL-2 Rs as detergent-resistant membrane complexes. Eur. J. Immunol. 20, 1497-1503.
6. Zhao, J., Furukawa, K., Fukumoto, S., Okada, M., Furugen, R., Miyazaki, H., Takamiya, K., Aizawa, S., Shiku, H., Matsuyama, T., Furukawa, K. (1999) Attenuation of IL 2 signal in the spleen cells of complex ganglioside-lacking mice. J. Biol. Chem. 274, 13744-13747.
7. Vereb G., Matkó, J., Vámosi, G., Ibrahim, S. M., Magyar, E., Varga, S., Szöllösi, J., Jenei, A., Gáspár Jr., R., Waldmann, T. A., Damjanovich, S. (2000) Cholesterol-dependent clustering of IL-2Rα and its colocalization with HLA and CD48 on T lymphoma cells suggest their functional association with lipid rafts. Proc. Natl. Acad. Sci. USA 97, 6013-6018.
8. Parolini, I., Sargiacomo, M., Lisanti, M. P., Peschle, C. (1996) Signal transduction and glycophosphatidylinositol-linked proteins (LYN, LCK, CD4, CD45, G proteins, and CD55) selectively localize in triton-insoluble plasma membrane domains of human leukemic cell lines and normal granulocytes. Blood 87, 3783-3794.
9. Baldari C. T., Telford, J. L., Acuto, O. (2000) EMBO workshop report: lymphocyte antigen receptor and coreceptor signaling, Siena, Italy, November 6-10, 1999. EMBO J. 19, 4857-4865.
10. Takaoka, A., Mitani, Y., Suemori, H., Sato, M., Yokochi, T., Noguchi, S., Tanaka, N., Taniguchi, T. (2000) Cross talk between IFN-γ and -α/β signaling components in caveolar membrane domains. Science 288, 2357-2360.
11. Brown, D. A., London, E. (1998) Functions of lipid rafts in biological membranes. Annu. Rev. Cell Dev. Biol. 14, 111-136.
12. Fra, A. M., Williamson, E., Simons, K., Parton, R. G. (1994) Detergent-insoluble glycolipid microdomains in lymphocytes in the absence of caveolae. J. Biol. Chem. 269, 30745-30748.
13. Acuto, O., Cantrell, D. (2000) T cell activation and the cytoskeleton. Annu. Rev. Immunol. 18, 165-184.
14. Saint-Ruf, C., Panigada, M., Azogul, O., Debey, P., von Boehmer, H., Grassi, F. (2000) Different initiation of pre-TCR and γδ TCR signaling. Nature 406, 524-527.
15. Marmor, M. D., Bachmann, M. F., Ohashi, P. S., Malek, T. R., Julius, M. (1999) Immobilization of glycosylphosphatidylinositol-anchored proteins inhibits T cell growth but not function. Int. Immunol. 11, 1381-1393.
16. Marmor, M. D., Julius, M. (2001) Role of lipid rafts in regulating interleukin-2 signaling. Blood 98, 1489-1497.
17. Lamaze, C., Dujeancourt, A., Baba, T., Lo, C. G., Benmerah, A., Dautry-Versat, A. (2001) Interleukin 2 receptors and detergent-resistant membrane domains define a clathrin-independent endocytic pathway. Mol. Cell 7, 661-671.
18. Lin, J. X., Migone, T. S., Tsang, M., Friedmann, M., Weatherbee, J. A., Zhou, L., Yamauchi, A., Bloom, E. T., Mietz, J., John, S., Leonard, W. J. (1995). The role of shared R motifs and common stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15. Immunity 2, 331-339.
19. Elliot, L. H., Carlson, S. L., Morford, L. A., McGillis, J. P. (1995). Preparation, characterization and use of human and rodent lymphocytes, monocytes, and neutrophils. In Methods of Neuroscience and Neuroimmunology (M. I. Phillips, D. Evans, eds.), San Diego, CA, Academic, 115-150.
20. lck. Transplant. Proc. 31, 822-824.
21. Bacon, C. M., McVicar, D. W., Ortaldo, J. R., Rees, R. C., O'Shea, J. J., Johnston, J. A. (1995) IL-12 (IL-12) induces tyrosine phosphorylation of JAK-2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12. J. Exp. Med. 181, 399-404.
22. Sundvold, V., Torgersen, K. M., Post, N. H., Marti, F., King, P. D., Røttingen, J. A., Spurkland, A., Lea, T. (2000) T cell-specific adapter protein inhibits T cell activation by modulating Lck activity. J. Immunol. 165, 2927-2931.
23. Xavier, R., Brennan, T., Li, Q., McCormack, C., Seed, B. (1998) Membrane compartmentation is required for efficient T cell activation. Immunity 8, 723-732.
24. Rock, M. T., Brooks, W. H., Roszman, T. L. (1997) Calcium-dependent signaling pathways in T cells. Potential role of calpain, protein tyrosine phosphatase 1b, and p130Cas in integrin-mediated signaling events. J. Biol. Chem. 272, 33377-33383.
25. Tuosto, L., Parolini, I., Schröder, S., Sargiacomo, M., Lanzavecchia, A., Viola, A. (2001) Organization of plasma membrane functional rafts upon T cell activation. Eur. J. Immunol. 31, 345-349.
26. Lin, J-X., Bhat, N. K., John, S., Quele, W. S., Leonard, W. J. (1993) Characterization of the human interleukin-2 receptor beta-chain gene promoter: regulation of promoter activity by ets gene products. Mol. Cell. Biol. 13, 6201-6210.
27. Kabouridis, P. S., Janzen, J., Magee, A., Ley, S. C. (2000) Cholesterol depletion disrupts lipid rafts and modulates the activity of multiple signaling pathways in T lymphocytes. Eur. J. Immunol. 30, 954-963.
28. Simons, K., Toomre, D. (2000) Lipid rafts and signal transduction. Nat. Rev. Mol. Cell Biol. 1, 31-39.
29. Resh, M. D. (1993) Interaction of tyrosine kinase oncoproteins with cellular membranes. Biochem. Biophys. Acta 1155, 307-322.
30. Johnston, J. A., Bacon, C. M., Riedy, M. C., O'Shea, J. J. (1996) Signaling by IL-2 and related cytokines: JAKs, STATs, and relationship to immunodeficiency. J. Leukoc. Biol. 60, 441-452.
31. Prior, I. A., Harding, A., Yan, J., Sluimer, J., Parton, R. G., Hancock, J. F. (2001) GTP-dependent segregation of H-ras from lipid rafts is required for biological activity. Nat. Cell Biol. 3, 368-375.
32. Goldman, F., Crabtree, J., Hollenback, C., Koretzky, G. (1997) Sequestration of p56(lck) by gp120, a model for TCR desensitization. J. Immunol. 158, 2017-2024.
33. Turner, C. E., Newton, M. R., Shotton, D. M. (1988) Cytoskeletal involvement in the sequential capping of rat thymocyte surface glycoproteins. J. Cell Sci. 89, 309-319.
34. Deckert, M., Ticchioni, M., Bernard, A. (1996) Endocytosis of GPI-anchored proteins in human lymphocytes: role of glycolipid-based domains, actin cytoskelton, and protein kinases. J. Cell Biol. 133, 791-799.
35. Harder, T., Simons, K. (1999) Clusters of glycolipid and glycophosphatidylinositol-anchored proteins in lymphoid cells: accumulation of actin regulated by local tyrosine phosphorylation. Eur. J. Immunol. 29, 556-562.
36. Goebel, J., Forrest, K., Roszman, T. L. (1999) Tubulin polymerization modulates IL-2 R signaling in T cells. FASEB J. 13, A950 (abstract).
37. Palestini, P., Pitto, M., Tedeschi, G., Ferraretto, A., Parenti, M., Brunner, J., Masserini, M. (2000) Tubulin anchoring to glycolipid-enriched, detergent-resistant domains of the neuronal plasma membrane. J. Biol. Chem. 275, 9978-9985.
38. Thatte, H., Bridges, K. R., Golan, D. E. (1994) Microtubule inhibitors differentially affect translational movement, cell surface expression, and endocytosis of transferrin Rs in K562 cells. J. Cell. Physiol. 160, 345-357.
39. Jin, M., Snider, M. D. (1993) Role of microtubules in transferrin R complex transport from the cell surface to endosomes and the Golgi complex. J. Biol. Chem. 268, 18390-18397.
40. Kelly, R. B. (1990) Microtubules, membrane traffic, and cell organization. Cell 61, 5-7.
41. 2-Adrenergic R internalization, endosomal sorting, and plasma membrane recycling are regulated by rab GTPases. J. Biol. Chem. 275, 27221-27228.
42. Hémar, A., Subtil, A., Lieb, M., Morelon, E., Hellio, R., Dautry-Varsat, A. (1995) Endocytosis of IL 2 Rs in human T lymphocytes: distinct intracellular localization and fate of the R α, β, and γ chains. J. Cell Biol. 129, 55-64.
43. Ilangumaran, S., Hoessli, D. C. (1998) Effects of cholesterol depletion by cyclodextrin on the sphingolipid microdomains of the plasma membrane. Biochem. J. 335, 433-440.