Depot-specific expression of fibroblast growth factors in human adipose tissue

Obesity Research

Volumn 10, Issue 7, 2002, Pages 608-616

  Gabrielsson, Britt G ^a   Johansson, Jenny M ^a   Jennische, Eva ^b   Jernås, Margareta ^a   Itoh, Yoshiaki ^a   Peltonen, Markku ^b   Olbers, Torsten ^b   Lönn, Lars ^b   Lönroth, Hans ^b   Sjöström, Lars ^b   Carlsson, Björn ^a,b   Carlsson, Lena M S ^a   Lönn, Malin ^a,c  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

DNA microarray; Immunohistochemistry; Mesothelial cells; Quantitative polymerase chain reaction

Indexed keywords

FGF9 PROTEIN, HUMAN; FGFR1 PROTEIN, HUMAN; FGFR2 PROTEIN, HUMAN; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 1; FIBROBLAST GROWTH FACTOR 9; FIBROBLAST GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR RECEPTOR 1; FIBROBLAST GROWTH FACTOR RECEPTOR 2; PROTEIN TYROSINE KINASE;

ADIPOCYTE; ADIPOSE TISSUE; ADULT; ARTICLE; BODY COMPOSITION; CHEMISTRY; DNA MICROARRAY; GENE EXPRESSION; GENETICS; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; MIDDLE AGED; NUCLEIC ACID HYBRIDIZATION; OBESITY; OMENTUM; POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADIPOCYTES; ADIPOSE TISSUE; ADULT; BODY COMPOSITION; FIBROBLAST GROWTH FACTOR 1; FIBROBLAST GROWTH FACTOR 9; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; NUCLEIC ACID HYBRIDIZATION; OBESITY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OMENTUM; POLYMERASE CHAIN REACTION; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 1; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 2; RECEPTORS, FIBROBLAST GROWTH FACTOR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 0036635942     PISSN: 10717323     EISSN: None     Source Type: Journal    
DOI: 10.1038/oby.2002.83     Document Type: Article

References (41)

1. Powers CJ, McLeskey SW, Wellstein A. Fibroblast growth factors, their receptors and signaling. Endocr Relat Can. 2000; 7:165-97.
2. Crandall DL, Hausman GJ, Kral JG. A review of the microcirculation of adipose tissue: anatomic, metabolic, and angiogenic perspectives. Microcirculation. 1997;4:211-32.
3. Hecht JT, Hood OJ, Schwartz RJ, Hennessey JC, Bernhardt BA, Horton WA. Obesity in achondroplasia. Am J Med Genet. 1988;31:597-602.
4. Vajo Z, Francomano CA, Wilkin DJ. The molecular and genetic basis of fibroblast growth factor receptor 3 disorders: the achondroplasia family of skeletal dysplasias, Muenke craniosynostosis, and Crouzon syndrome with acanthosis nigricans. Endocr Rev. 2000;21:23-39.
5. Kawaguchi N, Toriyama K, Nicodemou-Lena E, Inou K, Torii S, Kitagawa Y. De novo adipogenesis in mice at the site of injection of basement membrane and basic fibroblast growth factor. Proc Natl Acad Sci USA. 1998;95:1062-6.
6. Kissebah AH. Intra-abdominal fat: is it a major factor in developing diabetes and coronary artery disease? Diabetes Res Clin Pract. 1996;30(Suppl):25-30.
7. Krotkiewski M, Björntorp P, Sjöström L, Smith U. Impact of obesity on metabolism in men and women. Importance of regional adipose tissue distribution. J Clin Invest. 1983;72: 1150-62.
8. Larsson B, Svärdsudd K, Welin L, Wilhelmsen L, Björntorp P, Tibblin G. Abdominal adipose tissue distribution, obesity, and risk of cardiovascular disease and death: 13 year follow up of participants in the study of men born in 1913. Br Med J (Clin Res Ed). 1984;288;1401-4.
9. Carey DG, Nguyen TV, Campbell LV, Chisholm DJ, Kelly P. Genetic influences on central abdominal fat: a twin study. Int J Obes Relat Metab Disord. 1996;20:722-6.
10. Perusse L, Després JP, Lemieux S, Rice T, Rao DC, Bouchard C. Familial aggregation of abdominal visceral fat level: results from the Quebec family study. Metabolism. 1996;45: 378-82.
11. DiGirolamo M, Fine JB, Tagra K, Rossmanith R. Qualitative regional differences in adipose tissue growth and cellularity in male Wistar rats fed ad libitum. Am J Physiol. 1998;274:R1460-R7.
12. Marques BG, Hausman DB, Martin RJ. Association of fat cell size and paracrine growth factors in development of hyperplastic obesity. Am J Physiol. 1998;275:R1898-R1908.
13. Varzaneh FE, Shillabeer G, Wong KL, Lau DC. Extracellular matrix components secreted by microvascular endothelial cells stimulate preadipocyte differentiation in vitro. Metabolism. 1994;43:906-12.
14. Hutley LJ, Herington AC, Shurety W, et al. Human adipose tissue endothelial cells promote preadipocyte proliferation. Am J Physiol. 2001;281:E1037-E44.
15. Ornitz DM, Itoh N. Fibroblast growth factors. Genome Biol. 2001;2:REVIEWS3005.
16. Kim I, Moon S, Yu K, Kim U, Koh GY. A novel fibroblast growth factor receptor-5 preferentially expressed in the pancreas(1). Biochim Biophys Acta. 2001;1518:152-6.
17. Sleeman M, Fraser J, McDonald M, et al. Identification of a new fibroblast growth factor receptor, FGFR5. Gene. 2001; 271:171-82.
18. Teichert-Kuliszewska K, Hamilton BS, Deitel M, Roncari DA. Augmented production of heparin-binding mitogenic proteins by preadipocytes from massively obese persons. J Clin Invest. 1992;90:1226-31.
19. Gabrielsson BG, Carlsson B, Carlsson LMS. Partial genome scale analysis of gene expression in human adipose tissue using DNA array. Obes Res. 2000;8:374-84.
20. Yamasaki M, Emoto H, Konishi M, et al. FGF-10 is a growth factor for preadipocytes in white adipose tissue. Biochem Biophys Res Commun. 1999;258:109-12.
21. Smith U, Sjöström L, Björntorp P. Comparison of two methods for determining human adipose cell size. J Lipid Res. 1972;13:822-4.
22. Chowdhury B, Sjöström L, Alpsten M, Kostanty J, Kvist H, Löfgren R. A multicompartment body composition technique based on computerized tomography. Int J Obes Relat Metab Disord. 1994;18:219-34.
23. Tartaglia M, Fragale A, Battaglia PA. A competitive PCR-based method to measure human fibroblast growth factor receptor 1-4 (FGFR 1-4) gene expression. DNA Cell Biol. 2001;20:367-79.
24. Miller DL, Ortega S, Bashayan O, Basch R, Basilico C. Compensation by fibroblast growth factor 1 (FGF1) does not account for the mild phenotypic defects observed in FGF2 null mice. Mol Cell Biol. 2000;20:2260-8.
25. Guo L, Degenstein L, Fuchs E. Keratinocyte growth factor is required for hair development but not for wound healing. Genes Dev. 1996;10:165-75.
26. Min H, Danilenko DM, Scully SA, et al. Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless. Genes Dev. 1998;12:3156-61.
27. Colvin JS, White AC, Pratt SJ, Ornitz DM. Lung hypoplasia and neonatal death in Fgf9-null mice identify this gene as an essential regulator of lung mesenchyme. Development. 2001;128:2095-106.
28. Colvin JS, Green RP, Schmahl J, Capel B, Ornitz DM. Male-to-female sex reversal in mice lacking fibroblast growth factor 9. Cell. 2001;104:875-89.
29. van Hinsbergh VWH, Kooistra T, Scheffer MA, van Bockel JH, van Muijen GNP. Characterization and fibrinolytic properties of human omental tissue mesothelial cells. Comparison with endothelial cells. Blood. 1990;75:1490-7.
30. Cronauer MV, Stadlmann S, Klocker H, et al. Basic fibroblast growth factor synthesis by human peritoneal mesothelial cells. Am J Pathol. 1999;155:1977-84.
31. Giri D, Ropiquet F, Ittmann M. FGF9 is an autocrine and paracrine prostatic growth factor expressed by prostatic stromal cells. J Cell Physiol. 1999;180:53-60.
32. Krieger-Brauer HI, Kather H. Antagonistic effects of different members of the fibroblast and platelet-derived growth factor families on adipose conversion and NADPH-dependent H2O2 generation in 3T3 L1-cells. Biochem J. 1995;307:549-56.
33. Ornitz DM, Xu J, Colvin JS, et al. Receptor specificity of the fibroblast growth factor family. J Biol Chem. 1996;271: 15292-7.
34. Kan M, Wu X, Wang F, McKeehan WL. Specificity for fibroblast growth factors determined by heparan sulfate in a binary complex with the receptor kinase. J Biol Chem. 1999; 274:15947-52.
35. Fernig DG, Chen HL, Rahmoune H, Descamps S, Boilly B, Hondermarck H. Differential regulation of FGF-1 and -2 mitogenic activity is related to their kinetics of binding to heparan sulfate in MDA-MB-231 human breast cancer cells. Biochem Biophys Res Commun. 2000;267:770-6.
36. Lefebvre AM, Laville M, Vega N, et al. Depot-specific differences in adipose tissue gene expression in lean and obese subjects. Diabetes. 1998;47:98-103.
37. Montague CT, Prins JB, Sanders L, et al. Depot-related gene expression in human subcutaneous and omental adipocytes. Diabetes. 1998;47:1384-91.
38. Montague CT, Prins JB, Sanders L, Digby JE, O'Rahilly S. Depot-and sex-specific differences in human leptin mRNA expression: implications for the control of regional fat distribution. Diabetes. 1997;46:342-7.
39. Shimomura I, Funahashi T, Takahashi M, et al. Enhanced expression of PAI-1 in visceral fat: possible contributor to vascular disease in obesity. Nat Med. 1996;2:800-3.
40. Eriksson P, Van Harmelen V, Hoffstedt J, et al. Regional variation in plasminogen activator inhibitor-1 expression in adipose tissue from obese individuals. Thromb Haemost. 2000;83:545-8.
41. Dusserre E, Moulin P, Vidal H. Differences in mRNA expression of the proteins secreted by the adipocytes in human subcutaneous and visceral adipose tissues. Biochim Biophys Acta. 2000;1500:88-96.