Nε-carboxymethyllysine in diabetic and non-diabetic polyneuropathies

Acta Neuropathologica

Volumn 104, Issue 1, 2002, Pages 45-52

  Haslbeck, K M ^a   Schleicher, E D ^b   Fries, U ^b   Kirchner, A ^a   Neundorfer B ^a   Heuss, D ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Advanced glycosylation; N Carboxymethyllysine; Oxidative stress; Polyneuropathies

Indexed keywords

6 N CARBOXYMETHYLLYSINE; ANTIOXIDANT; BIOLOGICAL MARKER; REACTIVE OXYGEN METABOLITE; DRUG DERIVATIVE; LYSINE; N(6) CARBOXYMETHYLLYSINE; N(6)-CARBOXYMETHYLLYSINE;

ADULT; AGED; ALCOHOLISM; ANTIOXIDANT ACTIVITY; CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY; CLINICAL ARTICLE; CONTROLLED STUDY; CYANOCOBALAMIN DEFICIENCY; DIABETIC NEUROPATHY; DISEASE CLASSIFICATION; FEMALE; GLYCOSYLATION; HEREDITARY MOTOR SENSORY NEUROPATHY; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INFLAMMATORY CELL; MALE; MONONUCLEAR CELL; NEOVASCULARIZATION (PATHOLOGY); NERVE BIOPSY; OXIDATIVE STRESS; PATHOGENESIS; POLYNEUROPATHY; PRIORITY JOURNAL; REVIEW; SURAL NERVE; ARTICLE; BIOPSY; CHEMISTRY; METABOLISM; MIDDLE AGED; PATHOLOGY; POLYRADICULONEUROPATHY; WESTERN BLOTTING;

ADULT; AGED; BIOPSY; BLOTTING, WESTERN; CHARCOT-MARIE-TOOTH DISEASE; DIABETIC NEUROPATHIES; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LYSINE; MALE; MIDDLE AGED; OXIDATIVE STRESS; POLYRADICULONEUROPATHY, CHRONIC INFLAMMATORY DEMYELINATING; SURAL NERVE;

EID: 0036634467     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-002-0518-8     Document Type: Review

References (65)

1. Ames PR, Alves J, Murat I, Isenberg DA, Noorooz-Zadeh J (1999) Oxidative stress in systemic lupus erythematosus and allied conditions with vascular involvement. Rheumatology 38:529-534
2. ε-carboxymethyllysine on proteins. A mechanism for producing advanced glycation end products at sites of inflammation. J Clin Invest 104:103-113
3. Baeurle PA, Henkel T (1994) Function and activation of NF-κB in the immune system. J Clin Invest 12:141-179
4. Baichwal VR, Baeurle PA (1997) Apoptosis: activate NF-kappa B or die? Curr Biol 7:94-96
5. Baynes JW (1991) Perspectives in diabetes. Role of oxidative stress in development of complications in diabetes. Diabetes 40:405-412
6. Beamish NG, Stolinski C, Thomas PK, King RBM (1991) Freeze fracture observations on normal and abnormal human perineurial tight junctions: alterations in diabetic polyneuropathy. Acta Neuropathol 81:269-279
7. Bierhaus A, Chevion S, Chevinon M, Hofmann M, Quenhenberger P, Illmer T, Luther T, Berentshtein E, Tritschler H, Müller M, Wahl P, Ziegler R, Nawroth P (1997) Advanced glycation end product-induced activation of NF-κB is suppressed by α-lipoic acid in cultured endothelial cells. Diabetes 46:1481-1490
8. Bischoff A (1971) Die alkoholische Polyneuropathie: Klinische, ultrastrukturelle und pathogenetische Aspekte. Dtsch Med Wochenschr 96:317-322
9. Bosch-Morell F, Martinez-Soriano F, Colell A, Fernandez-Checa JC, Romero FJ (1998) Chronic ethanol feeding induces cellular antioxidants decrease and oxidative stress in rat peripheral nerves. Effect of S-adenosyl-L-methionine and N-acetyl-L-cysteine. Free Radic Biol Med 25:365-368
10. Botez MI, Peyronnard JM, Bachevalier J, Charron L (1978) Polyneuropathy and folate deficiency. Arch Neurol 35:581-584
11. Both AA, Khalifah RG, Hudson BG (1996) Thiamine pyrophosphate and pyridoxamine inhibit the formation of antigenic advanced glycation end-products: comparison with aminoguanidine. Biochem Biophys Res Commun 220:113-119
12. Brownlee M (1992) Glycation products and the pathogenesis of diabetic complications. Diabetes Care 15:1835-1843
13. Brownlee M, Vlassara H, Cerami A (1988) Advanced glycosylation end products in tissue and in the biochemical basis of diabetic complications. N Engl J Med 318:1315-1321
14. Cameron NE, Cotter MA (1997) The etiopathogenesis of diabetic neuropathy: vascular and metabolic theories. In: Boulton AJM (ed) Diabetic neuropathy. Marius Press, Camforth, pp 121-146
15. Cameron NE, Cotter MA, Archibald V, Dines KC, Maxfield EK (1994) Anti-oxidant and pro-oxidant effects on nerve conduction velocity, endoneurial blood flow and oxygen tension in non-diabetic and streptozotocin-diabetic rats. Diabetologia 37:449-459
16. Chambers JC, McGregor A, Jean-Marie J, Obeid OA, Kooner JS (1999) Demonstration of rapid onset vascular endothelial dysfunction after hyperhomocysteinemia: an effect reversible with vitamin C therapy. Circulation 9:1156-1160
17. Claus D (1987) Mangelneuropathien. In: Neundörfer B, Schimrigk K, Soyka D (eds) Polyneuritiden und Polyneuropathien. VCH, Weinheim, pp 410-442
18. Claus D, Egers R, Engelhardt A, Neundörfer B, Warecka K (1985) Ethanol and polyneuropathy. Acta Neurol Scand 72: 312-316
19. Consensus Panel (1988) Report and recommendations of the San Antonio conference on diabetic neuropathy. Diabetes Care 11:592-597
20. Cordell JL, Falini B, Erber WN, Ghosh AK, Abdulaziz Z, MacDonald S, Pulford KA, Stein H, Mason DY (1984) Immunoenzymatic labelling of monoclonal antibodies using immune complex of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes). J Histochem Cytochem 32: 219-229
21. Cotter MA, Cameron NE (1997) The aetiopathogenesis of diabetic neuropathy: metabolic theories. In: Boulton AJM (ed) Diabetic neuropathy. Marius press, Camforth, pp 121-146
22. Dyck PJ, Chance P, Labedo R, Carney JA (1993) Hereditary motor and sensory neuropathies. In: Dyck PJ, Thomas PK, et al (eds) Peripheral neuropathy, 3rd edn. Saunders, Philadephia, pp 1094-1113
23. Eaton RP, Qualls C, Bicknell J, Sibbitt WL, King MK, Griffey RH (1996) Structure-function relationships within peripheral nerves in diabetic neuropathy: the hydration hypothesis. Diabetologia 39:439-446
24. Engelhardt A, Lörler H, Neundörfer B (1993) Immunohistochemical findings in vasculitic neuropathies. Acta Neurol Scand 87:318-321
25. Feldman EL, Stevens MJ, Greene DA (1997) Pathogenesis of diabetic neuropathy. Clin Neurosci 4:365-370
26. E-carboxymethyllysine independently of glycohemoglobin concentrations. Diabetologia 42:603-607
27. Heuss D, Probst-Cousin S, Kayser C, Neundörfer B (2000) Cell death in vasculitic neuropathy Muscle Nerve 23:999-1004
28. Jackson E, Amato AA, Barohn RJ (1996) Isolated vitamin E deficiency. Muscle Nerve 19:1161-1165
29. Jacobsen DW (1998) Homocysteine and vitamins in cardiovascular disease. Clin Chem 44:1833-43
30. Kanani PM, Sinkey CA, Browning RL, Allaman M, Knapp HR, Haynes WG (1999) Role of oxidant stress in endothelial dysfunction produced by experimental hyperhomocyst(e)inemia in humans. Circulation 100:1161-1168
31. Kaspar M, Roehlecke C, Witt M, Fehrenbach H, Hofer A, Miyata T, Weigert C, Funk RHW, Schleicher ED (2000) Induction of apoptosis by glyoxal in human embryonic lung epithelial cell line L132. Am J Respir Cell Mol Biol 23:485-491
32. E-Carboxymethyllysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression. J Biol Chem 44:31740-31749
33. Lightfoot RW, Michel BA, Bloch DA, et al (1990) The American College of Rheumatology criteria for classification of polyarteritis nodosa. Arthritis Rheum 33:1088-1093
34. Ligier S, Fortin PR, Newkirk MM (1998) A new antibody in rheumatoid arthritis targeting glycated IgG: IgM anti-IgG-AGE. Br J Rheumatol 37:1307-14
35. Low PA, Nickander KK, Tritschler HJ (1997) The roles of oxidative stress and antioxidant treatment in experimental diabetic neuropathy. Diabetes 46:38-42
36. Lyons TJ, Jenkins AJ (1997) Glycation, oxidation, and lipoxidation in the development of complications of diabetes: a carbonyl stress hypothesis. Diabetes Rev 5:365-391
37. Masi AT, Hunder GG, Lie JT, et al (1990) The American College of Rheumatology criteria for classification of Churg-Strauss syndrome (allergic granulomatosis and angiitis). Arthritis Rheum 33:1094-1100
38. McCombe PA, Mc Leod JG (1984) The peripheral neuropathy of vitamin B12 deficiency. J Neurol Sci 66:117-126
39. Nerlich AG, Schleicher ED (1999) N(epsilon)-carboxymethyllysine in atherosclerotic vascular lesions as a marker for local oxidative stress. Arteriosclerosis 144:41-47
40. Neundörfer B (1998) Klinik und Diagnose der Polyneuropathien. Dtsch Med Wochenschr 23:1519-1522
41. Newkirk MM, Le Page K, Niwa T, Rubin L (1998) Advanced glycation endproducts (AGE) on IgG, a target for circulating antibodies in North American Indians with rheumatoid arthritis (RA). Cell Mol Biol 44:1129-38
42. Olsson Y (1990) Microenvironment of peripheral nerve system under normal and pathological conditions. Crit Rev Neurobiol 5:265-311
43. Podusolo JF, Curran GL (1992). Increased permeability over the blood-nerve barrier of albumin glycated in vitro and in vivo from patients with diabetic neuropathy. Proc Natl Acad Sci USA 89:2218-2222
44. Prasad K(I 999) Homocysteine, a risk factor for cardiovascular disease. Int J Angiol 8:76-86
45. Report from an ad hoc subcommittee of American Academy of Neurology AIDS Task Force (1991) Research criteria for diagnosis of chronic inflammatory demyelinating polyneuropathy (CIDP). Neurology 41:617-618
46. Rittner HL, Hafner V, Klimiuk PA, Szweda LI, Goronzy JJ, Weyand CM (1999) Aldose reductase functions as a detoxification system for lipid peroxidation products in vasculitis. J Clin Invest 103:1007-1013
47. Satoi H, Oka N, Kawasaki T, Miyamoto K, Akiguchi I, Kimura J (1998) Mechanisms of tissue injury in vasculitic neuropathy. Neurology 50:492-496
48. E-(carboxymethyl)lysine in human tissue in diabetes and aging. J Clin Invest 99: 457-468
49. E-carboxymethyllysine in normal and inflamed human intestinal tissues. In: O'Brien J, Nurston HE, Crabbe MJC, Ames JA (eds) Maillard reactions in foods and medicine. Royal Society of Chemistry, Cambridge, pp 316-321
50. Schmidt AM, Hori O, Chen JX, Li JF, Crandall J, Zhang J, Cao R, Yan SD, Brett J, Stern D (1995) Advanced glycated end-products interacting with their endothelial receptor induce expression of vascular cell adhesion molecule 1 (VCAM 1) in cultured human endothelial cells and in mice: a potential mechanism for accelerated vasculopathy of diabetes. J Clin Invest 96:1395-1403
51. Scott JM (1999) Folate and vitamin B12. Proc Nutr Soc 58:441-448
52. Sinatra ST, DeMarco J (1995) Free radicals, oxidative stress, oxidized low density lipoprotein (LDL), and the heart: antioxidants and other strategies to limit cardiovascular damage. Conn Med 59:579-88
53. Stevens MJ, Obrosova I, Cao X, Van Huysen C, Greene DA (2000) Effects of DL-alpha-lipoic acid on peripheral nerve conduction, blood flow, energy metabolism, and oxidative stress in experimental diabetic neuropathy. Diabetes 49:1006-15
54. E-carboxymethyllysine-protein adducts, an advanced glycation endproduct. Diabetologia 40:1380-1387
55. Takeuchi M, Makita Z, Yanagisawa K, Kameda Y, Koike T (1999) Detecting of noncarboxymethyllysine and carboxymethyllysine advanced glycation end products (AGE) in serum of diabetic patients. Mol Med 5:393-405
56. Thiele K, Bierhaus A, Autschbach F, Hofmann M, Stremel W, Thiele K, Ziegler R, Nawroth PP (1999) Cell specific effects of glucocorticoid treatment on the NF-kappa Bp65/I kappa B alpha system in patients with Crohn's disease. Gut 45:693-704
57. Thomas PK, Tomlinson DR (1993) Diabetic and hypoglycemic neuropathy. In: Dyck PJ, Thomas PK, et al (eds) Peripheral neuropathy, 3rd edn. Saunders, Philadelphia, pp 1219-1250
58. Thomas PK, Berthold CH, Ochoa J (1993) Microscopic anatomy of the peripheral nervous system. In: Dyck PJ, Thomas PK, et al (eds.) Peripheral neuropathy, 3rd edn. Saunders, Philadelphia, pp 30-32
59. Thome J, Zang J, Davids E, Weijers HG, Wiesbeck GA, Boning J, Riederer P, Gerlach M.(1997) Evidence for increased oxidative stress in alcohol dependent patients provided by quantification of in vivo salicylate hydroxylation. Alcohol Clin Exp Res 21:82-85
60. Van Dam PS, Bravenboer B (1997) Oxidative stress and antioxidant treatment in diabetic neuropathy. Neurosci Res Commun 21:21-28
61. Wang XL, Duarte N, Cai H, Adachi T, Sim AS, Cranney G, Wilcken DE (1999) Relationship between total plasma homocysteine, polymorphisms of homocysteine metabolism related enzymes, risk factors and coronary artery disease in the Australian hospital-based population. Arteriosclerosis 146:133-140
62. Wautier JL, Wautier MP, Schmidt AM, et al (1996) Receptor mediated cell dysfunction in diabetic vasculopathy. Soluble receptor for advanced glycosylated endproducts blocks hypermeability in diabetic rats. J Clin Invest 97:238-243
63. Weir DG, Scott JM (1995) The biochemical basis of the neuropathy in cobalamin deficiency. Baillieres Clin Haematol 8:479-497
64. Windebank AJ (1993) Polyneuropathy due to nutritional deficiency and alcoholism. In: Dyck PJ, Thomas PK, et al (eds) Peripheral neuropathy, 3rd edn. Saunders, Philadephia, pp 1310-1313
65. Yan SD, Schmidt AM, Anderson GM, Zhang J, Brett J, Zou YS, Pinsky D, Stern D (1994) Enhanced cellular oxidant stress by interaction of advanced glycosylated endproducts with their receptor/binding proteins. J Biol Chem 269:9889-9897