Rapid static adhesion of human naïve neutrophil to naïve xenoendothelium under physiologic flow is independent of Galα1,3-gal structures

Journal of Leukocyte Biology

Volumn 71, Issue 6, 2002, Pages 932-940

  Sheikh, Sajila ^a   Parhar, Ranjit ^a   Al Mohanna, Futwan ^a  

^a KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

Author keywords

Calcium; Flow stress; Xenotransplantation

Indexed keywords

CD11B ANTIGEN; GALACTOSYLGALACTOSE; INTERCELLULAR ADHESION MOLECULE 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CARBOHYDRATE ANALYSIS; CELL ADHESION; CELL INTERACTION; CONTROLLED STUDY; ENDOTHELIUM; HUMAN; HUMAN CELL; HYDRODYNAMICS; NATURAL KILLER CELL; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; SHEAR STRESS; SWINE; XENOGRAFT; XENOTRANSPLANTATION;

ANIMALS; AORTA; CALCIUM SIGNALING; CELL ADHESION; CELLS, CULTURED; DISACCHARIDES; ENDOTHELIUM, VASCULAR; HUMANS; NEUTROPHILS; SWINE; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA; SUS SCROFA;

EID: 0036622715     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (70)

1. Sachs, D. H., Winn, H. J., Russell, P. S. (1971) The immunologic response to xenografts. Recognition of mouse H-2 histocompatibility antigens by the rat. J. Immunol. 107, 481-492.
2. Auchincloss Jr., H. (1988) Xenogeneic transplantation. Transplantation 46, 1-20.
3. Bouwman, E., de Bruin, R. W. F., Marquet, R. L., Jeekel, J. (1989) Prolongation of graft survival in sensitized xenotransplantation. Transplant. Proc. 21, 551-552.
4. Platt, J. L., Lindman, B. J., Chen, H., Spitalnik, S. L., Bach, F. H. (1990) Endothelial cell antigens recognized by xenoreactive human natural antibodies. Transplantation 50, 817-822.
5. Sandrin, M. S., McKenzie, I. F. (1994) Gal alpha (1,3)gal, the major xenoantigen(s) recognised in pigs by human natural antibodies. Immunol. Rev. 141, 169-190.
6. Cooper, D. K., Koren, E., Oriol, R. (1994) Oligosaccharides and discordant xenotransplantation. Immunol. Rev. 141, 31-58.
7. Galili, U., Mather, B. A., Buehler, J., Shohet, S. B. (1985) Human natural anti-alpha-galactosyl IgG. II. The specific recognition of alpha (1-3)-linked galactose residues. J. Exp. Med. 162, 573-582.
8. Collins, B. H., Cotterell, A. H., McCurry, K. R., Alvarado, C. G., Magee, J. C., Parker, W., Platt, J. L. (1995) Cardiac xenografts between primate species provide evidence for the importance of the alpha-galactosyl determinant in hyperacute rejection. J. Immunol. 154, 5500-5510.
9. Vaughan, H. A., Loveland, B, E., Sandrin, M. S. (1994) Gal alpha(1,3)gal is the major xenoepitope expressed on pig endothelial cells recognized by naturally occurring cytotoxic human antibodies. Transplantation 58, 879-882.
10. Sandrin, M. S., Vaughan, H. A., Dabkowski, P. L., McKenzie, I. F. (1993) Anti-pig IgM antibodies in human serum react predominantly with Gal-(alpha 1-3)gal epitopes. Proc. Natl. Acad. Sci. USA 90, 11391-11395.
11. Galili, U., Clark, M. R., Shohet, S. B., Buehler, J., Macher, B. A. (1987) Evolutionary relationship between the natural anti-Gal antibody and the Gal-alpha 1-3gal epitope in primates. Proc. Natl. Acad. Sci. USA 84, 1369-1373.
12. Galili, U., Anaraki, F., Thall, A., Hill-Black, C., Radic, M. (1993) One percent of human circulating B lymphocytes are capable of producing the natural anti-Gal antibody. Blood 82, 2485-2493.
13. Good, A. H., Cooper, D. K., Malcolm, A. J., Ippolito, R. M., Koren, E., Neethling, F. A., Ye, Y., Zuhdi, N., Lamontagne, L. R. (1994) Identification of carbohydrate structures that bind human antiporcine antibodies: implications for discordant xenografting in humans. Transplant. Proc. 24, 59-62.
14. Cooper, D. K., Good, A. H., Koren, E., Oriol, R., Malcolm, A. J., Ippolito, R. M., Neethling, F. A., Ye, Y., Romano, E., Zuhdi, N. (1993) Identification of alpha-galactosyl and other carbohydrate epitopes that are bound by human anti-pig antibodies: relevance to discordant xenografting in man. Transpl. Immunol. 1, 198-205.
15. Platt, J. L., Lindman, B. J., Geller, R. L., Noreen, H. J., Swanson, J. L., Dalmasso, A. P., Bach, F. H. (1991) The role of natural antibodies in the activation of xenogenic endothelial cells. Transplantation 52, 1037-1043.
16. Dalmasso, A. P., Vercellotti, G. M., Fischel, R. J., Bolman, R. M., Bach, F. H., Platt, J. L. (1992) Mechanism of complement activation in the hyperacute rejection of porcine organs transplanted into primate recipients. Am. J. Pathol. 140, 1157-1166.
17. Bach, F. H., Robson, S. C., Ferran, C., Winkler, H., Millan, M. T., Stuhlmeier, K. M., Vanhove, B., Blakely, M. L., van der Werf, W. J., Hofer, E., et al. (1994) Endothelial cell activation and thromboregulation during xenograft rejection. Immunol. Rev. 141, 5-30.
18. Magee, J. C., Platt, J. L. (1994) Xenotransplantation: molecular mechanisms and therapeutic implications. Ther. Immunol. 1, 45-58.
19. Artrip, J. H., Itescu, S., Minanov, O. P., Kwiatkowski, P. A., Michler, R. E. (1997) Cardiac transplantation. Curr. Opin. Cardiol. 12, 172-178.
20. Al-Mohanna, F. A., Collisons, K. S., Parhar, R. S., Kwaasi, A. A., Meyer, B. F., Saleh, S. S., Allen, S. R., Al-Sedairy, S. T., Stem, D. M., Yacoub, M. H. (1997) Activation of naive xenogeneic but not allogeneic endothelial cells by human naive neutrophils: a potential occult barrier to xenotransplantation. Am. J. Pathol. 151, 111-120.
21. Sheikh, S., Parhar, R., Kwaasi, A., Collison, K., Yacoub, M., Stern, D., Al-Mohanna, F. (2000) Alpha-gal-independent dual recognition and activation of xenogeneic endothelial cells and human naïve natural killer cells. Transplantation 70, 917-928.
22. Smith, C. W., Kishimoto, T. K., Abbassi, O., Hughes, B., Rothlein, R., McIntire, L. V., Butcher, E., Anderson, D. C., Abbass, O. (1991) Chemotactic factors regulate lectin adhesion molecule 1 (LECAM-1)-dependent neutrophil adhesion to cytokine-stimulated endothelial cells in vitro. J. Clin. Investig. 87, 609-618.
23. Williams, A. F. (1991) Out of equilibrium. Nature 352, 473-474.
24. Tozeren, A., Ley, K. (1992) How do selectins mediate leukocyte rolling in venules? Biophys. J. 63, 700-709.
25. Hammer, D. A., Apte, S. M. (1992) Simulation of cell rolling and adhesion on surfaces in shear flow: general results and analysis of selectin-mediated adhesion. Biophys. J. 63, 35-57.
26. Springer, T. A. (1994) Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76, 301-314.
27. Carlos, T. M., Harlan, J. M. (1994) Leukocyte-endothelial adhesion molecules. Blood 84, 2068-2101.
28. Vestweber, D., Blanks, J. E. (1.999) Mechanisms that regulate the function of the selectins and their ligands. Physiol. Rev. 79, 181-213.
29. Pober, J. S., Cotran, R. S. (1990) The role of endothelial cells in inflammation. Transplantation 50, 537-544.
30. Adams, D. H., Nash, G. B. (1996) Disturbance of leucocyte circulation and adhesion to the endothelium as factors in circulatory pathology. Br. J. Anaesth. 77, 17-31.
31. Robinson, L. A., Tu, L., Steeber, D. A., Preis, O., Platt, J. L., Tedder, T. F. (1998) The role of adhesion molecules in human leukocyte attachment to porcine vascular endothelium: implications for xenotransplantation. J. Immunol. 161, 6931-6938.
32. Morigi, M., Zoja, C., Colleoni, S., Angioletti, S., Imberti, B., Remuzzi, A., Remuzzi, G. (1998) Xenogeneic human serum promotes leukocyte adhesion to porcine endothelium under flow conditions, possible through the activation of the transcription factor NF-kappa B. Xenotransplantation 5, 57-60.
33. Kishimoto, T. K. (1991) A dynamic model for neutrophil localization to inflammatory sites. J. NIH Res. 3, 75-77.
34. Tsukurov, O. I., Kwolek, C. J., L'Italien, G. J., Benbrahim, A., Milinazzo, B. B., Conroy, N. E., Gertler, J. P., Orkin, R. W., Abbott, W. M. (2000) The response of adult human saphenous vein endothelial cells to combined pressurized pulsatile flow and cyclic strain, in vitro. Ann. Vasc. Surg. 14, 260-267.
35. Lum, R. M., Wiley, L. M., Barakat, A. I. (2000) Influence of different forms of fluid shear stress on vascular endothelial TGF-beta1 mRNA expression. Int. J. Mol. Med. 5, 635-641.
36. Al-Mohanna, F. A., Hallett, M. B. (1987) Actin polymerisation modifies stimulus-oxidase coupling in neutrophils. Biochem. Biophys. Acta 927, 366-371.
37. Jaffe, E. A., Nachman, R. L., Becker, C. G., Minick, C. R. (1973) Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J. Clin. Investig. 52, 2745-2756.
38. Cooke, B. M., Usami, S., Perry, I., Nash, G. B. (1993) A simplified method for culture of endothelial cells and analysis of adhesion of blood cells under conditions of flow. Microvasc. Res. 45, 33-45.
39. Buttrum, S. M., Hatton, R., Nash, G. B. (1993) Selectin-mediated rolling of neutrophils on immobilised platelets. Blood 82, 1165-1174.
40. Sheikh, S., Nash, G. B. (1996) Continuous activation and deactivation of integrin cd11b/cd18 during de novo expression enables rolling neutrophils to immobilize on platelets. Blood 87, 5040-5050.
41. Collison, K. S., Kwaasi, A. A., Parhar, R. S., Al-Sedairy, S. T., AlMohanna, F. A. (1995) Monomeric human IgE evokes a transient calcium rise in individual human neutrophils. J. Leukoc. Biol. 58, 459-467.
42. Grynikiewicz, G., Poenie, M., Tsien, R. Y. (1985) A new generation of Ca+ indicators with greatly improved florescence properties. J. Biol. Chem. 260, 3440-3450.
43. Al-Mohanna, F. A., Caddy, K. W. T., Bolsover, S. R. (1994) The nucleus is insulated from large cytosolic calcium changes. Nature 367, 745-750.
44. Rainger, G. E., Fisher, A., Shearman, C., Nash, G. B. (1995) Adhesion of flowing neutrophils to cultured endothelial cells after hypoxia and reoxygenation in vitro. Am. J. Physiol. 269. H1398-H1406.
45. Tanemura, M., Maruyama, S., Galili, U. (2000) Differential expression of alpha-gal epitopes (Galalpha1-3galbeta1-4GlcNAc-R) on pig and mouse organs. Transplantation 69, 187-190.
46. Tanemura, M., Yin, D., Chong, A. S., Galili, U. (2000) Differential immune responses to alpha-gal epitopes on xenografts and allografts: implications for accommodation in xenotransplantation. J. Clin. Investig. 105, 301-310.
47. Maruyama, S., Cantu 3rd, E., Pernis, B., Galili, U., Godman, G., Stern, D. M., Andres, G. (1999) Alpha-galactosyl antibody redistributes alphagalactosyl at the surface of pig blood and endothelial cells. Transpl. Immunol. 7, 101-106.
48. Fryer, J., Firca, J., Leventhal, J., Blondin, B., Malcolm, A., lvancic, D., Gandhi, R., Shah, A., Pao, W., Abecassis, M., Kaufman, D., Stuart, F., Anderson, B. (1999) IgY antiporcine endothelial cell antibodies effectively block human antiporcine xenoantibody binding. Xenotransplantation 6, 98-109.
49. Romano, E., Neethling, F. A., Nilsson, K., Kosanke, S., Shimizu, A., Magnusson, S., Svensson, L., Samuelsson, B., Cooper, D. K. (1999) Intravenous synthetic alphaGal saccarides delay hyperacute rejection following pig-to-baboon heart transplantation. Xenotransplantation 6, 36-42.
50. Luo, Y., Wen, J., Luo, C., Cummings, R. D., Cooper, D. K. (199) Pig xenogeneic antigen modification with green coffee bean alpha-galactoside. Xenotransplantation 6, 238-248.
51. Miyagawa, S., Tanemura, M., Koyota, S., Koma, M., Ikeda, Y., Shirakura, R., Taniguchi, N. (1999) Masking and reduction of the Galactose-alpha1,3-galactose (alpha-Gal) epitope, the major xenoantigen in swine, by the glycosyltransferase gene transfection. Biochem. Biophys. Res. Commun. 264, 611-614.
52. Pearse, M. J., Cowan, P. J., Shinkel, T. A., Chen, C. G., d'Apice, A. J. (1999) Anti-xenograft immune responses in alpha 1,3-galactoyltransferase knock-out mice. Subcell Biochem. 32, 281-310.
53. Kirk, A. D., Heinle, J. S., Mault, J. R., Sanfilippo, F. (1993) Ex vivo characterisation of human anti-porcine hyperacute cardiac rejection. Transplantation 56, 785-793.
54. Inveradi, L., Samaja, M., Motterlini, R., Mangili, F., Bender, J. R., Pardi, R. (1992) Early recognition of a discordant xenogeneic organ by human circulating lymphoytes. J. Immunol. 149, 1416-1423.
55. Binnele, B., Thibault, G., Nivet, H., Gruel, Y., Bardos, P. Lebranchu, Y. (1996) Human lymphocyte adhesion to xenogeneic porcine endothelial cells: modulation by human TNF-alpha and involvement of VLA-4 and LFA-1. Transpl. Immunol. 4, 265-270.
56. Smith, C. W., Marlin, S. D., Rothlein, R., Toman, C., Anderson, D. C. (1989) Cooperative interactions of LFA-1 and Mac-1 with intercellular adhesion molecule-1 in facilitating adherence and transendothelial migration of human neutrophils in vitro. J. Clin. Investig. 83, 2008-2017.
57. Linke, R., Wagner, F., Hammer, C. (1998) Analysis of the microcirculation during xenogeneic liver perfusion in the guinea pig-rat model. The contribution of leukocytes to the rejection process. Transpl. Int. 11, S457-S460.
58. Woods, N. M., Cuthbertson, K. S., Cobbold, P. H. (1986) Repetitive transient rises in cytoplasmic free calcium in hormone-stimulated hepatocytes. Nature 319, 600-602.
59. Oancea, E., Meyer, T. (1998) Protein kinase C as a molecular machine for decoding calcium and diacylglycerol signals. Cell 95, 307-318.
60. De Koninck, P., Schulman, H. (1998) Sensitivity of CaM kinase 11 to the frequency of Ca2+ oscillations. Science 279, 227-230.
61. Pober, J. S., Gimbrone Jr., M. A., Lapierre, L. A., Mendrick, D. L., Fiers, W., Rothlein, R., Springer, T. A. (1986) Overlapping patterns of activation of human endothelial cells by interleukin 1, tumour necrosis factor, and immune interferon. J. Immunol. 137, 1893-1896.
62. Rainger, G. E., Wautier, M. P., Nash, G. B., Wautier, J. L. (1996) Prolonged E-selectin induction by monocytes potentiates the adhesion of flowing neutrophils to cultured endothelial cells. Br. J. Haematol. 92, 192-199.
63. Batten, P., Yacoub, M. H., Rose, M. L. (1996) Effect of human cytokines (IFN-gamma, TNF-alpha, IL-1beta, IL-4) on porcine endothelial cells: induction of MHC and adhesion molecules and functional significance of these changes. Immunology 87, 127-133.
64. Vallee, I., Watier, H., Thibault, G., Lalmanach, A. C., Lacord, M., Gruel, Y., Lebranchu, Y., Salmon, H., Bardos, P. (1995) Human TNF-alpha induces major histocompatibility complex class-II molecules on porcine endothelial cells without affecting the proliferative response of human lymphocytes. Transplant. Proc. 27, 1678-1679.
65. Watier, H., Vallee, I., Thibault, G., Lalmanach, A. C., Lacord, M., Gruel, Y., Lebranchu, Y., Salmon, H., Bardos, P. (1994) Effect of human inflammatory cytokines on porcine endothelial cell MHC molecule expression: unique role for TNF-α in MHC class II induction. Transplant. Proc. 26, 1152-1155.
66. Marinos, G., Rossol, S., Carucci, P., Wong, P. Y., Donaldson, P., Hussain, M. J., Vergani, D., Portmann, B. C., Williams R., Naoumov, N. V. (2000) Immunopathogenesis of hepatits B virus recurrence after liver transplantation. Transplantation 69, 559-568.
67. Nordoy, I., Muller, F., Nordal, K. P., Rollag, H., Lien, E., Aukrust, P., Froland, S. S. (2000) The role of the tumour necrosis factor system and interleukin-10 during cytomegalovirus infection in renal transplant recipients. J. Infect. Dis. 181, 51-57.
68. Saumweber, D. M., Bergmann, R., Gokal, M., Hammer, C. (1994) Hyperacute rejection in an ex vivo model of renal xenografting. Role of the mediator response and its pharmacologic manipulation by the specific platelet-activating factor antagonist WEB 2086BS. Transplantation 57, 358-363.
69. Kovarik, J., Koulmanda, M., Madel, T. E. (1997) The role of cytokines during rejection of foetal pig and foetal mouse pancreas grafts in nonobese diabetic mice, Transpl. Immunol. 5, 307-314.
70. Wooley, S. T., Whyte, A., Licence, S. T. K., Haskard, D. O., Wooding, F. B. P., Binns, R. M. (1995) Differences in E-selectin expression and leucocyte infiltration induced by inflammatory agents in a novel subcutaneous sponge matrix model. Immunology 84, 55-63.