Induction of oral tolerance in mice by continuous feeding with β-lactoglobulin and milk

Bioscience, Biotechnology and Biochemistry

Volumn 66, Issue 6, 2002, Pages 1287-1294

  Mizumachi, Koko ^a   Kurisaki, Jun Ichi ^b  

^a NATIONAL INSTITUTE OF LIVESTOCK AND GRASSLAND SCIENCE   (Japan)

^b NATIONAL INSTITUTE OF AGROBIOLOGICAL SCIENCES   (Japan)

Author keywords

Epitope; Oral tolerance; Synthetic peptide; lactoglobulin

Indexed keywords

ANTIBODY; ANTIGEN; CYTOKINE; EPITOPE; LACTOGLOBULIN;

ANIMAL; ANTIBODY SPECIFICITY; ARTICLE; BAGG ALBINO MOUSE; BIOSYNTHESIS; CHEMISTRY; CYTOLOGY; FEMALE; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; LYMPH NODE; LYMPHOCYTE ACTIVATION; MILK; MILK ALLERGY; MOUSE; ORAL DRUG ADMINISTRATION; T LYMPHOCYTE;

ADMINISTRATION, ORAL; ANIMALS; ANTIBODIES; ANTIBODY SPECIFICITY; ANTIGENS; CYTOKINES; EPITOPES, T-LYMPHOCYTE; FEMALE; IMMUNE TOLERANCE; LACTOGLOBULINS; LYMPH NODES; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MILK; MILK HYPERSENSITIVITY; T-LYMPHOCYTES;

EID: 0036616352     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.66.1287     Document Type: Article

References (25)

1. Faria, A. M. and Weiner, H. L., Oral tolerance: mechanisms and therapeutic applications. Adv. Immunol., 73, 153-264 (1999).
2. Strobel, S. and Mowat, A. M., Immune responses to dietary antigens: oral tolerance. Immunol. Today, 19, 173-181 (1998).
3. Whitacre, C. C., Gienapp, I. E., Orosz, C. G., and Bitar, D. M., Oral tolerance in experimental autoimmune encephalomyelitis. III. Evidence for clonal anergy. J. Immunol., 147, 2155-2163 (1991).
4. Chen, Y., Inobe, J., Marks, R., Gonnella, P., Kuchroo, V. K., and Weiner, H. L., Peripheral deletion of antigen-reactive T cells in oral tolerance. Nature, 376, 177-180 (1995).
5. Weiner, H. L., Oral tolerance: immune mechanisms and treatment of autoimmune diseases. Immunol. Today, 18, 335-343 (1997).
6. Chen, Y., Kuchroo, V. K., Inobe, J., Hafler, D. A., and Weiner, H. L., Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science, 265, 1237-1240 (1994).
7. Friedman, A. and Weiner, H. L., Induction of anergy or active suppression following oral tolerance is determined by antigen dosage. Proc. Natl. Acad. Sci. U S A, 91, 6688-6692 (1994).
8. Hoyne, G. F. and Thomas, W. R., T-cell responses to orally administered antigens. Study of the kinetics of lymphokine production after single and multiple feeding. Immunology, 84, 304-309 (1995).
9. Melamed, D., Fishman-Lovell, J., Uni, Z., Weiner, H. L., and Friedman, A., Peripheral tolerance of Th2 lymphocytes induced by continuous feeding of ovalbumin. Int. Immunol., 8, 717-724 (1996).
10. Aschaffenburg, R. and Drewry, J., Improved method for the preparation of crystalline β-lactoglobulin and a-lactoalbulin from cow’s milk. Biochem. J., 65, 273-277 (1957).
11. Tsuji, N. M., Kurisaki, J., Mizumachi, K., and Kaminogawa, S., Localization of T-cell determinants on bovine β-lactoglobulin. Immunol. Lett., 37, 215-221 (1993).
12. Mosmann, T. R. and Coffman, R. L., Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol., 7, 145-173 (1989).
13. Steavens, T. L., Bossie, A., Sanders, V. M., Fernandez-Botran, R., Coffman, R. L., Mosmann, T. R., and Vitetta, E. S., Regulation of antibody isotype secretion by subsets of antigen-specific helper T cells. Nature, 334, 255 (1988).
14. Fritsche, R., Pahud, J. J., Pecquet, S., and Pfeifer, A., Induction of systemic immunologic tolerance to β-lactoglobulin by oral administration of a whey protein hydrolysate. J. Allergy Clin. Immunol., 100, 266-273. (1997).
15. Kato, C., Sato, K., Eishi, Y., and Nakamura, K., The influence of initial exposure timing to β-lactoglobulin on oral tolerance induction. J. Allergy Clin. Immunol., 104, 870-878 (1999).
16. Pecquet, S., Pfeifer, A., Gauldie, S., and Fritsche, R., Immunoglobulin E suppression and cytokine modulation in mice orally tolerized to β-lactoglobu-lin. Immunology, 96, 278-285 (1999).
17. Mizumachi, K., Kurisaki, J., and Kaminogawa, S., Localization of sequential antigenic determinants on bovine β-casein with synthetic peptides and antisera from mouse, rabbit, and goat. Biosci. Biotechnol. Biochem., 63, 911-916 (1999).
18. Ametani, A., Kim, S. M., Kaminogawa, S., and Yamauchi, K., Antibody response of three different strains of mice to as1-casein analyzed by using proteolytic and synthetic peptides. Biochem. Biophys. Res. Commun., 154, 876-882 (1988).
19. Kaminogawa, S. and Ametani, A., Milk proteins. In “Structure of Antigens,” Regenmortel, M.H.V., CRC Press, Florida, pp. 387-411 (1996).
20. Grivel, J.-C. and Smith-Gill, S. J. Lysozyme: Antigenic structure as defined by antibody and T cell responses. In “Structure of Antigens,” Regenmortel, M.H.V., CRC Press, Frorida, pp. 91-154 (1996).
21. Kim, S. M., Enomoto, A., Hachimura, S., Yamauchi, K., and Kaminogawa, S., Serum antibody response elicited by a casein diet is directed to only limited determinants of as1-casein. Int. Arch. Allergy Immunol., 101, 260-265 (1993).
22. Hachimura, S., Fujikawa, Y., Enomoto, A., Kim, S. M., Ametani, A., and Kaminogawa, S., Differential inhibition of T and B cell responses to individual antigenic determinants in orally tolerized mice. Int. Immunol., 6, 1791-1797 (1994).
23. Gammon, G. and Sercarz, E., How some T cells escape tolerance induction. Nature, 342, 183-185 (1989).
24. Tsuji, N. M., Mizumachi, K., and Kurisaki, J., Interleukin-10-secreting Peyer’s patch cells are responsible for active suppression in low-dose oral tolerance. Immunology, 103, 458-464 (2001).
25. Marth, T., Ring, S., Schulte, D., Klensch, N., Strober, W., Kelsall, B. L., Stallmach, A., and Zeitz, M., Antigen-induced mucosal T cell activation is followed by Th1 T cell suppression in continuously fed ovalbumin TCR-transgenic mice. Eur. J. Immunol, 30, 3478-3486 (2000).