Distinct proteins encoded by alternative transcripts of the PURG gene, located contrapodal to WRN on chromosome 8, determined by differential termination/polyadenylation

Nucleic Acids Research

Volumn 30, Issue 11, 2002, Pages 2417-2426

  Liu, Hong ^a   Johnson, Edward M ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; COMPLEMENTARY DNA; CYTOSINE; DNA BINDING PROTEIN; HELICASE; MESSENGER RNA; PUR GAMMA PROTEIN; TRANSCRIPTION FACTOR SP1; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; CANCER TISSUE; CARBOXY TERMINAL SEQUENCE; CHROMOSOME 8P; CONTROLLED STUDY; DNA SEQUENCE; GENE CLUSTER; GENE LOCATION; GENE SWITCHING; GENETIC CODE; GENETIC TRANSCRIPTION; HELA CELL; HUMAN; HUMAN CELL; INTRON; MALE; NUCLEOTIDE SEQUENCE; POLYADENYLATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN FAMILY; REPORTER GENE; RNA SPLICING; TESTIS; TRANSCRIPTION INITIATION; TRANSCRIPTION TERMINATION; WERNER SYNDROME;

EID: 0036606423     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/30.11.2417     Document Type: Article

References (49)

1. Sequence of cDNA comprising the human pur gene and sequence-specific single-stranded-DNA-binding properties of the encoded protein
2. The single-stranded DNA binding protein, Pur-alpha, binds HIV-1 TAR RNA and activates HIV-1 transcription
3. Puralpha: A multifunctional single-stranded DNA- and RNA-binding protein
4. Alterations in Pur(alpha) levels and intracellular localization in the CV-1 cell cycle
5. Activation of the JC virus Tat-responsive transcriptional control element by association of the Tat protein of human immunodeficiency virus 1 with cellular protein Pur alpha
6. Neural BC1 RNA associates with pur alpha, a single-stranded DNA and RNA binding protein, which is involved in the transcription of the BC1 RNA gene
7. Association of Puralpha with RNAs homologous to 7 SL determines its binding ability to the myelin basic protein promoter DNA sequence
8. Transcriptional regulation of neuronal nicotinic acetylcholine receptor genes. A possible role for the DNA-binding protein Puralpha
9. The PUR element stimulates transcription and is a target for single strand-specific binding factors conserved among vertebrate classes
10. Repression of transcriptional enhancer factor-1 and activator protein-1-dependent enhancer activity by vascular actin single-stranded DNA binding factor 2
11. The single-stranded DNA- and RNA-binding proteins pur alpha and pur beta link BC1 RNA to microtubules through binding to the dendrite-targeting RNA motifs
12. DNA-binding protein Pur alpha and transcription factor YY1 function as transcription activators of the neuron-specific FE65 gene promoter
13. Sequence of cDNAs encoding components of vascular actin single-stranded DNA-binding factor 2 establish identity to Puralpha and Purbeta
14. Deletions of PURA, at 5q31, and PURB, at 7p13, in myelodysplastic syndrome and progression to acute myelogenous leukemia
15. Ras-induced colony formation and anchorage-independent growth inhibited by elevated expression of Puralpha in NIH3T3 cells
16. Cell cycle arrest and morphological alterations following microinjection of NIH3T3 cells with Pur alpha
17. Association of human Pur alpha with the retinoblastoma protein, Rb, regulates binding to the single-stranded DNA Pur alpha recognition element
18. Basic local alignment search tool
19. Sp1-mediated transcription of the Werner helicase gene is modulated by Rb and p53
20. Structure and function of the human Werner syndrome gene promoter: Evidence for transcriptional modulation
21. Werner's syndrome a review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process
22. Family analysis of Werner's syndrom: A survey of 42 Japanese families with a review of the literature
23. Excess of rare cancers in Werner syndrome (adult progeria)
24. Positional cloning of the Werner's syndrome gene
25. The Werner syndrome protein: An update
26. Rapid production of full-length cDNAs from rare transcripts: Amplification using a single gene-specific oligonucleotide primer
27. Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs
28. MatInd and MatInspector: New fast and versatile tools for detection of consensus matches in nucleotide sequence data
29. Regulation of Puralpha gene transcription: Evidence for autoregulation of Puralpha promoter
30. Coordinate regulation of the human TAP1 and LMP2 genes from a shared bidirectional promoter
31. Identification of two initiator elements in the bidirectional promoter of the human dihydrofolate reductase and mismatch repair protein 1 genes
32. A bidirectional promoter connects the p14.5 gene to the gene for RNase P and RNase MRP protein subunit hPOP1
33. Mouse cdc21 only 0.5 kb upstream from dna-pkcs in a head-to-head organization: An implication of co-evolution of ATM family members and cell cycle regulating genes
34. The bidirectional promoter of the divergently transcribed mouse Surf-1 and Surf-2 genes
35. Identification and characterization of a bidirectional promoter from the intergenic region between the human DDX13 and RD genes
36. Identification of functional elements in the bidirectional promoter of the mouse Nthl1 and Tsc2 genes
37. Characterization of the bi-directional transcriptional control region between the human UFD1L and CDC45L genes
38. Expression of the murine RanBP1 and Htf9-c genes is regulated from a shared bidirectional promoter during cell cycle progression
39. A GC box in the bidirectional promoter is essential for expression of the human dihydrofolate reductase and mismatch repair protein 1 genes
40. Identification of a novel sequence element in the common promoter region of human collagen type IV genes, involved in the regulation of divergent transcription
41. Expression profiles and intergenic structure of head-to-head oriented Brca1 and Nbr1 genes
42. A bidirectional promoter connects the poly(ADP-ribose) polymerase 2 (PARP-2) gene to the gene for RNase P RNA. Structure and expression of the mouse PARP-2 gene
43. Soggy, a spermatocyte-specific gene, lies 3.8 kb upstream of and antipodal to TEAD-2, a transcription factor expressed at the beginning of mouse development
44. CpG-rich islands and the function of DNA methylation
45. DNA methylation from embryo to adult
46. Interaction of HIV-1 Tat with Puralpha in nuclei of human glial cells: Characterization of RNA-mediated protein-protein binding
47. Conservation in human and mouse Pur alpha of a motif common to several proteins involved in initiation of DNA replication
48. Evolutionarily conserved interaction between CstF-64 and PC4 links transcription, polyadenylation and termination
49. Transcriptional termination and coupled polyadenylation in vitro