Purα: A multifunctional single-stranded DNA- and RNA-binding protein

Nucleic Acids Research

Volumn 28, Issue 17, 2000, Pages 3197-3205

  Gallia, Gary L ^a,b   Johnson, Edward M ^c   Khalili, Kamel ^a  

^a Temple University   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; CYCLIN A; DNA; REGULATOR PROTEIN; RNA; RNA BINDING PROTEIN; SINGLE STRANDED DNA BINDING PROTEIN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR E2F; TRANSCRIPTION FACTOR SP1; VIRUS LARGE T ANTIGEN; VIRUS PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DNA BINDING PROTEIN; PURA PROTEIN, HUMAN; SINGLE STRANDED DNA; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL FUNCTION; CELL GROWTH; CELL PROLIFERATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DNA SEQUENCE; EUKARYOTIC CELL; GENE DELETION; GENE LOCUS; GENE TARGETING; GENETIC CODE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; JC VIRUS; LYMPHATIC SYSTEM TUMOR; MOUSE; MYELOID LEUKEMIA; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYOMA VIRUS; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN STRUCTURE; RNA TRANSLATION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; VIRUS GENE; VIRUS REPLICATION; AMINO ACID SEQUENCE; ANIMAL; CELL DIVISION; CHEMISTRY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; MOLECULAR EVOLUTION; MOLECULAR GENETICS; REVIEW; SEQUENCE ALIGNMENT;

ANIMALIA; DNA VIRUSES; EUKARYOTA; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; JC VIRUS; POLYOMAVIRUS; RNA VIRUSES;

AMINO ACID SEQUENCE; ANIMALS; CELL DIVISION; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DNA, SINGLE-STRANDED; DNA-BINDING PROTEINS; EVOLUTION, MOLECULAR; GENE EXPRESSION REGULATION; HUMANS; MOLECULAR SEQUENCE DATA; RNA-BINDING PROTEINS; SEQUENCE ALIGNMENT; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 0034257920     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (65)

1. Sequence of cDNA comprising the human pur gene and sequence-specific single-stranded-DNA-binding properties of the encoded protein
2. Cooperative action of cellular proteins YB-1 and Purα with the tumor antigen of the human JC polyomavirus determines their interaction with the viral lytic control element
3. Association of human Purα with the retinoblastoma protein, Rb, regulates binding to the single-stranded DNA Purα recognition element
4. Interaction of the single-stranded DNA-binding protein Purα with the human polyomavirus JC virus early protein T-antigen
5. Reciprocal interaction between two cellular proteins, Purα and YB-1, modulates transcriptional activity of JCVCY in glial cells
6. Self-association of Purα is mediated by RNA
7. Activation of the JC virus Tat-responsive transcriptional control element by association of the Tat protein of human immunodeficiency virus 1 with cellular protein Purα
8. Conservation in human and mouse Purα of a motif common to several proteins involved in initiation of DNA replication
9. SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene
10. Amino acid sequences common to rapidly degraded proteins: The PEST hypothesis
11. Transcriptional activation: A complex puzzle with few easy pieces
12. Transcriptional regulation of human JC polyomavirus promoters by cellular proteins YB-1 and Purα in glial cells
13. A 39-kDa DNA-binding protein from mouse brain stimulates transcription of myelin basic protein gene in oligodendrocytes
14. DNA-binding protein Purα and transcription factor YY1 function as transcription activators of the neuron-specific FE65 gene promoter
15. Sequence of cDNAs encoding components of vascular actin single-stranded DNA-binding factor 2 establish identity to Purα and Purβ
16. Identification of (CAG)(n) and (CGG)(n) repeat-binding proteins, CAGERs expressed in mature neurons of the mouse brain
17. The HeLa pur factor binds single-stranded DNA at a specific element conserved in gene flanking regions and origins of DNA replication
18. Association of Purα with RNAs homologous to 7SL determines its binding ability to the myelin basic protein promoter DNA sequence
19. Evidence that replication of human neurotropic JC virus DNA in glial cells is regulated by the sequence-specific single-stranded DNA-binding protein Purα
20. Association of Purα and E2F-1 suppresses transcriptional activity of E2F-1
21. Transcriptional regulation of neuronal nicotinic acetylcholine receptor genes. A possible role for the DNA-binding protein Purα
22. A developmentally regulated DNA-binding protein from mouse brain stimulates myelin basic protein gene expression
23. Characterization of the single-strand-specific BPV-1 origin binding protein, SPSF I, as the HeLa Purα factor
24. Identification of a cellular protein that binds to Tat-responsive element of TGFβ-1 promoter in glial cells
25. Plant interstitial telomere motifs participate in the control of gene expression in root meristems
26. Evidence for inhibition of MyEF-2 binding to MBP promoter by MEF-1/Purα
27. The single-stranded DNA binding protein, Pur-α, binds HIV-1 TAR RNA and activates HIV-1 transcription
28. Association of HIV-1 Tat with the cellular protein, Purα, is mediated by RNA
29. RNA-dependent DNA binding activity of the Pur factor, potentially involved in DNA replication and gene transcription
30. Cellular and molecular aspects of myelin protein gene expression
31. Analysis of the proximal transcriptional element of the myelin basic protein gene
32. Myelin basic protein gene transcription: Identification of proximal and distal cis-acting regulatory elements
33. Regulation of myelin basic protein gene transcription by Sp1 and Purα: Evidence for association of Sp1 and Purα in brain
34. Identification of a sequence-specific single-stranded DNA binding protein that suppresses transcription of the mouse myelin basic protein gene
35. Plasticity of vascular smooth muscle alpha-actin gene transcription. Characterization of multiple, single-and double-strand specific DNA-binding proteins in myoblasts and fibroblasts
36. Activation of muscle-specific actin gene promoter in serum-stimulated fibroblasts
37. Negative regulation of the vascular smooth muscle alpha-actin gene in fibroblasts and myoblasts: Disruption of enhancer function by sequence-specific single-stranded-DNA-binding proteins
38. Repression of transcriptional enhancer factor-1 and activator protein-1-dependent enhancer activity by vascular actin single-stranded DNA binding factor 2
39. Molecular interactions between single-stranded DNA-binding proteins associated with an essential MCAT element in the mouse smooth muscle α-actin promoter
40. The single-stranded DNA-binding proteins, Purα, Purβ and MSY1 specifically interact with an exon 3-derived mouse vascular smooth muscle α-actin messenger RNA sequence
41. A novel regulatory element of a nicotinic acetylcholine receptor gene interacts with a DNA binding activity enriched in rat brain
42. Transcriptional regulation of neuronal nicotinic acetylcholine receptor genes. Functional interactions between Sp1 and the rat beta 4 subunit gene promoter
43. Effects of chronic exposure of NG108-15 cells to morphine or ethanol on binding of nuclear factors to cAMP-response element
44. Modulation by chronic morphine administration of single-stranded cAMP response element (ssCRE) binding proteins in the mouse cerebellum
45. Involvement of a single-stranded DNA binding protein, ssCRE-BP/Puraα, in morphine dependence
46. Characterization of a nuclear factor that enhances DNA binding activity of ssCRE-BP/Purα, a single-stranded DNA binding protein
47. Calmodulin functions as an activator of Purα binding to single-stranded purine-rich DNA elements (PUR elements)
48. A single stranded DNA-binding protein, ssCRE-BP/Purα, in rat lung and its increase in allergic airway inflammation
49. The PUR element stimulates transcription and is a target for single strand-specific binding factors conserved among vertebrate classes
50. The far upstream element-binding proteins comprise an ancient family of single-strand DNA-binding transactivators
51. Loss of FBP function arrests cellular proliferation and extinguishes c-myc expression
52. Unrestraining genetic processes with a protein-DNA hinge
53. Transcriptional regulation: Lessons from the human neurotropic polyomavirus, JCV
54. A novel sequence-specific DNA-binding protein, LCP-1, interacts with single-stranded DNA and differentially regulates early gene expression of the human neurotropic JC virus
55. Evidence that a sequence similar to TAR is important for induction of the JC virus late promoter by human immunodeficiency virus type 1 Tat
56. GC/GA rich sequence confers Tat-responsiveness to human neurotropic virus promoter, JCVL, in cells derived from CNS
57. Taking a new TAK on Tat transactivation
58. Alterations in Purα levels and intracellular localization in the CV-1 cell cycle
59. Cell cycle arrest and morphological alterations following microinjection of NIH3T3 cells with Purα
60. Localization of PURA, the gene encoding the sequence-specific single-stranded-DNA-binding protein Purα, to chromosome band 5q31
61. Cytogenetic and molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases
62. 5q-:Pathogenic importance of the common deleted region and clinical consequences of the entire deleted segment
63. The PURA gene, encoding the single-stranded DNA-binding protein Purα, as a marker for 5q31 alteration in myeloproliferative disorders, a potentially early step in induction of AML
64. The retinoblastoma protein and cell cycle control
65. Association of JC virus large T-antigen with myelin basic protein transcription factor (MEF-1/Purα) in hypomyelinated brains of mice transgenically expressing T antigen