Measurements of weak interactions between truncated substrates and a hammerhead ribozyme by competitive kinetic analysis: Implications for the design of new and efficient ribozymes with high sequece specificity

Nucleic Acids Research

Volumn 30, Issue 11, 2002, Pages 2383-2389

  Kasai, Yasuhiro ^a,b   Shizuku, Hideki ^a,b   Takagi, Yasuomi ^b   Warashina, Masaki ^b   Taira, Kazunari ^b,c  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

RIBOZYME;

ARTICLE; COMPETITION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BINDING; ENZYME DEGRADATION; ENZYME INHIBITION; ENZYME KINETICS; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN MOTIF; TRANSPORT KINETICS;

BASE PAIR MISMATCH; BASE SEQUENCE; BINDING, COMPETITIVE; CATALYSIS; GENETIC ENGINEERING; HYDROLYSIS; KINETICS; MUTATION; NUCLEIC ACID CONFORMATION; RNA, CATALYTIC; SUBSTRATE SPECIFICITY; THERMODYNAMICS;

EID: 0036606177     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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