Melphalan availability in hypoxia-inducible factor-1α+/+ and factor-1α-/- tumors is independent of tumor vessel density and correlates with melphalan erythrocyte transport

International Journal of Cancer

Volumn 99, Issue 4, 2002, Pages 514-519

  Wildiers, Hans ^a,b   Guetens, Gunter ^a   De Boeck, Gert ^a   Landuyt, Willy ^a   Verbeken, Eric ^a   Highley, Martin ^a   De Bruijn, Ernst A ^a   Van Oosterom, Allan T ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

Erythrocyte; Hypoxia; Melphalan; Transport; Tumor availability

Indexed keywords

ANTINEOPLASTIC AGENT; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MELPHALAN;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CHEMOTHERAPY; DRUG ERYTHROCYTE LEVEL; DRUG TRANSPORT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPOXIA; MOUSE; NONHUMAN; OXYGEN TRANSPORT; PLASMA; PRIORITY JOURNAL; SOLID TUMOR; TISSUE DISTRIBUTION; TUMOR BLOOD FLOW; TUMOR MODEL;

ANIMALS; ANTIGENS, CD34; ANTINEOPLASTIC AGENTS, ALKYLATING; BIOLOGICAL TRANSPORT; DISEASE MODELS, ANIMAL; ERYTHROCYTES; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LINEAR MODELS; MALE; MELPHALAN; MICE; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 0036605051     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.10391     Document Type: Article

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