Different Gi-coupled chemoattractant receptors signal qualitatively different functions in human neutrophils

Journal of Leukocyte Biology

Volumn 71, Issue 5, 2002, Pages 798-806

  Berger, Miles ^a   Budhu, Sadna ^a   Lu, Emily ^a   Li, Yongmei ^a   Loike, Devora ^a   Silverstein, Samuel C ^a   Loike, John D ^a  

^a College of Physicians and Surgeons ^*  (United States)

Author keywords

Fibrin; fMLP; H2O2; Integrins; LTB4

Indexed keywords

BETA2 INTEGRIN; CHEMOATTRACTANT; COLLAGEN; COLLAGEN TYPE 1; COLLAGEN TYPE 4; FIBRINOGEN; FORMYLMETHIONYLLEUCYLPHENYLALANINE; GUANINE NUCLEOTIDE BINDING PROTEIN; HYDROGEN PEROXIDE; INTERLEUKIN 8; LEUKOTRIENE B4; MATRIGEL; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CHEMOTAXIS; EXTRACELLULAR MATRIX; FLUORESCENCE ACTIVATED CELL SORTER; HUMAN; HUMAN CELL; LEUKOCYTE ADHERENCE; NEUTROPHIL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANTIGENS, CD18; CELL ADHESION; CELLS, CULTURED; CHEMOTACTIC FACTORS; CHEMOTAXIS, LEUKOCYTE; EXTRACELLULAR MATRIX PROTEINS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; HYDROGEN PEROXIDE; KINETICS; NEUTROPHILS; PERTUSSIS TOXIN; RECEPTORS, IMMUNOLOGIC; SIGNAL TRANSDUCTION; VIRULENCE FACTORS, BORDETELLA;

EID: 0036587679     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. Bokoch, G. M. (1995) Chemoattractant signaling and leukocyte activation. Blood 86, 1649-1660.
2. Loike, J. D., el Khoury, J., Cao, L., Richards, C. P., Rascoff, H., Mandeville, J. T., Maxfield, F. R., Silverstein, S. C. (1995) Fibrin regulates neutrophil migration in response to interleukin 8, leukotriene B4, tumor necrosis factor, and formyl-methionyl-leucyl-phenylalanine. J. Exp. Med. 181, 1763-1772.
3. Loike, J. D., Cao, L., Budhu, S., Marcantonio, E. E., El Khoury, J., Hoffman, S., Yednock, T. A., Silverstein, S. C. (1999) Differential regulation of betaintegrins by chemoattractants regulates neutrophil migration through fibrin. J. Cell Biol. 144, 1047-1056.
4. Weber, C., Katayama, J., Springer, T. A. (1996) Differential regulation of beta 1 and beta 2 integrin avidity by chemoattractants in eosinophils. Proc. Natl. Acad. Sci. USA 93, 10939-10944.
5. Nathan, C. F. (1987) Neutrophil activation on biological surfaces. Massive secretion of hydrogen peroxide in response to products of macrophages and lymphocytes. J. Clin. Investig. 80, 1550-1560.
6. Nathan, C., Srimal, S., Farber, C., Sanchez, E., Kabbash, L., Asch, A., Gailit, J., Wright, S. D. (1989) Cytokine-induced respiratory burst of human neutrophils: dependence on extracellular matrix proteins and CD11/CD18 integrins. J. Cell Biol. 109, 1341-1349.
7. Wright, S. D., Rao, P. E., Van Voorhis, W. C., Craigmyle, L. S., Iida, K., Talle, M. A., Westberg, E. F., Goldstein, G., Silverstein, S. C. (1983) Identification of the C3bi receptor of human monocytes and macrophages by using monoclonal antibodies. Proc. Natl. Acad. Sci. USA 80, 5699-5703.
8. Sadhu, C., Masinovsky, B., Staunton, D. E. (1998) Differential regulation of chemoattractant-stimulated beta 2, beta 3, and beta 7 integrin activity. J. Immunol. 160, 5622-5628.
9. Wright, S. D., Weitz, J. I., Huang, A. J., Levin, S. M., Silverstein, S. C., Loike, J. D. (1988) Complement receptor type three (CD11h/CD18) of human polymorphonuclear leukocytes recognizes fibrinogen. Proc. Natl. Acad. Sci. USA 85, 7734-7738.
10. Zhou, M., Diwu, Z., Panchuk-Voloshina, N., Haugland, R. P. (1997) A stable nonfluorescent derivative of resorufin for the fluorometric determination of trace hydrogen peroxide: applications in detecting the activity of phagocyte NADPH oxidase and other oxidases. Anal. Biochem. 253, 162-168.
11. Diamond, M. S., Staunton, D. E., Marlin, S. D., Springer, T. A. (1991) Binding of the integrin Mac-1 (CD11b/CD18) to the third immunoglobulin-like domain of ICAM-1 (CD54) and its regulation by glycosylation. Cell 65, 961-971.
12. Diamond, M. S., Springer, T. A. (1993) A subpopulation of Mac-1 (CD11b/CD18) molecules mediates neutrophil adhesion to ICAM-1 and fibrinogen. J. Cell Biol. 120, 545-556.
13. Avdi, N. J., Winston, B. W., Russel, M., Young, S. K., Johnson, G. L., Worthen, G. S. (1996) Activation of MEKK by formyl-methionyl-leucylphenylalanine in human neutrophils. Mapping pathways for mitogen-activated protein kinase activation. J. Biol. Chem. 271, 33598-33606.
14. Downey, G. P., Butler, J. R., Brumell, J., Borregaard, N., Kjeldsen, L., Sue, A. Q. A. K., Grinstein, S. (1996) Chemotactic peptide-induced activation of MEK-2, the predominant isoform in human neutrophils. Inhibition by wortmannin. J. Biol. Chem. 271, 21005-21011.
15. Huang, R., Lian, J. P., Robinson, D., Badwey, J. A. (1998) Neutrophils stimulated with a variety of chemoattractants exhibit rapid activation of p21-activated kinases (Paks): separate signals are required for activation and inactivation of paks. Mol. Cell. Biol. 18, 7130-7138.
16. Lian, J. P., Huang, R., Robinson, D., Badwey, J. A. (1999) Activation of p90RSK and cAMP response element binding protein in stimulated neutrophils: novel effects of the pyridinyl imidazole SB 203580 on activation of the extracellular signal-regulated kinase cascade. J. Immunol. 163, 4527-4536.
17. Pillinger, M. H., Feoktistov, A. S., Capodici, C., Solitar, B., Levy, J., Oei, T. T., Philips, M. R. (1996) Mitogen-activated protein kinase in neutrophils and enucleate neutrophil cytoplasts: evidence for regulation of cell-cell adhesion. J. Biol. Chem. 271, 12049-12056.
18. Thompson, H. L., Marshall, C. J., Saklatvala, J. (1994) Characterization of two different forms of mitogen-activated protein kinase kinase induced in polymorphonuclear leukocytes following stimulation by N-formylmethionyl-leucyl-phenylalanine or granulocyte-macrophage colony-stimulating factor. J. Biol. Chem. 269, 9486-9492.
19. Torres, M., Hall, F. L., O'Neill, K., (1993) Stimulation of human neutrophils with formyl-methionyl-leucyl-phenylalanine induces tyrosine phosphorylation and activation of two distinct mitogen-activated protein-kinases. J. Immunol. 150, 1563-1577.
20. Worthen, G. S., Avdi, N., Buhl, A. M., Suzuki, N., Johnson, G. L. (1994) FMLP activates Ras and Raf in human neutrophils. Potential role in activation of MAP kinase. J. Clin. Investig. 94, 815-823.
21. Zu, Y. L., Qi, J., Gilchrist, A., Fernandez, G. A., Vazquez-Abad, D., Kreutzer, D. L., Huang, C. K., Sha'afi, R. I. (1998) p38 Mitogen-activated protein kinase activation is required for human neutrophil function triggered by TNF-alpha or FMLP stimulation. J. Immunol. 160, 1982-1989.
22. Menegazzi, R., Busetto, S., Decleva, E., Cramer, R., Dri, P., Patriarca, P. (1999) Triggering of chloride ion efflux from human neutrophils as a novel function of leukocyte beta 2 integrins: relationship with spreading and activation of the respiratory burst. J. Immunol. 162, 423-434.
23. Gresham, H. D., Graham, I. L., Anderson, D. C., Brown, E. J. (1991) Leukocyte adhesion-deficient neutrophils fail to amplify phagocytic function in response to stimulation. Evidence for CD11b/CD18-dependent and -independent mechanisms of phagocytosis. J. Clin. Investig. 88, 588-597.
24. Dougherty, G. J., Dransfield, I., Hogg, N. (1988) Identification of a novel monocyte cell surface molecule involved in the generation of antigen-induced proliferative responses. Eur. J. Immunol. 18, 2067-2071.
25. Bohnsack, J. F., Akiyama, S. K., Damsky, C. H., Knape, W. A., Zimmerman, G. A. (1990) Human neutrophil adherence to laminin in vitro. Evidence for a distinct neutrophil integrin receptor for laminin. J. Exp. Med. 171, 1221-1237.
26. Carter, W. G., Wayner, E. A., Bouchard, T. S., Kaur, P. (1990) The role of integrins alpha 2 beta 1 and alpha 3 beta 1 in cell-cell and cell-substrate adhesion of human epidermal cells. J. Cell Biol. 110, 1387-1404.
27. Damaj, B. B., McColl, S. R., Mahana, W., Crouch, M. F., Naccache, P. H. (1996) Physical association of Gi2alpha with interleukin-8 receptors. J. Biol. Chem. 271, 12783-12789.
28. Igarashi, T., Yokomizo, T., Tsutsumi, O., Taketani, Y., Shimizu, T., Izumi, T. (1999) Characterization of the leukotriene B4 receptor in porcine leukocytes. Separation and reconstitution with heterotrimeric GTP-binding proteins. Eur. J. Biochem. 259, 419-425.
29. Wenzel-Seifert, K., Hurt, C. M., Seifert, R. (1998) High constitutive activity of the human formyl peptide receptor. J. Biol. Chem. 273, 24181-24189.
30. Yokomizo, T., Izumi, T., Chang, K., Takuwa, Y., Shimizu, T. (1997) A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis. Nature 387, 620-624.
31. Lad, P. M., Olson, C. V., Smiley, P. A. (1985) Association of the N-formyl-Met-Leu-Phe receptor in human neutrophils with a GTP-binding protein sensitive to pertussis toxin. Proc. Natl. Acad. Sci. USA 82, 869-873.
32. Klinker, J. F., Wenzel-Seifert, K., Seifert, R. (1996) G-protein-coupled receptors in HL-60 human leukemia cells. Gen. Pharmacol. 27, 33-54.
33. Shappell, S. B., Toman, C., Anderson, D. C., Taylor, A. A., Entman, M. L., Smith, C. W. (1990) Mac-1 (CD11b/CD18) mediates adherence-dependent hydrogen peroxide production by human and canine neutrophils. J. Immunol. 144, 2702-2711.
34. Liu, Y., Janeway Jr., C. A. (1992) Cells that present both specific ligand and costimulatory activity are the most efficient inducers of clonal expansion of normal CD4 T cells. Proc. Natl. Acad. Sci. USA 89, 3845-3849.
35. Ashton-Rickardt, P. G., Bandeira, A., Delaney, J. R., Van Kaer, L., Pircher, H. P., Zinkernagel, R. M., Tonegawa, S. (1994) Evidence for a differential avidity model of T cell selection in the thymus. Cell 76, 651-663.
36. Schepers, T. M., Brier, M. E., McLeish, K. R. (1992) Quantitative and qualitative differences in guanine nucleotide binding protein activation by formyl peptide and leukotriene B4 receptors. J. Biol. Chem. 267, 159-165.
37. Senogles, S. E. (1994) The D2 dopamine receptor isoforms signal through distinct Gi alpha proteins to inhibit adenylyl cyclase. A study with site-directed mutant Gi alpha proteins. J. Biol. Chem. 269, 23120-23127.
38. Didsbury, J. R., Snyderman, R. (1987) Molecular cloning of a novel human GTP-binding protein and its potential role in chemoattractant stimulusresponse coupling. Trans. Assoc. Am. Physicians 100, 99-108.
39. Beals, C. R., Wilson, C. B., Perlmutter, R. M. (1987) A small multigene family encodes Gi signal-transduction proteins. Proc. Natl. Acad. Sci. USA 84, 7886-7890.
40. Downes, G. B., Gautam, N. (1999) The G protein subunit gene families. Genomics 62, 544-552.
41. Kleuss, C., Scherubl, H., Hescheler, J., Schultz, G., Wittig, B. (1992) Different beta-subunits determine G-protein interaction with transmembrane receptors. Nature 358, 424-426.
42. Kleuss, C., Scherubl, H., Hescheler, J., Schultz, G., Wittig, B. (1993) Selectivity in signal transduction determined by gamma subunits of heterotrimeric G proteins. Science 259, 832-834.
43. Azpiazu, I., Cruzblanca, H., Li, P., Linder, M., Zhuo, M., Gautam, N. (1999) A G protein gamma subunit-specific peptide inhibits muscarinic receptor signaling. J. Biol. Chem. 274, 35305-35308.
44. Maier, U., Babich, A., Macrez, N., Leopoldt, D., Gierschik, P., Illenberger, D., Nurnberg, B. (2000) Gbeta 5gamma 2 is a highly selective activator of phospholipid-dependent enzymes. J. Biol. Chem. 275, 13746-13754.
45. Virchow, S., Ansorge, N., Rubben, H., Siffert, G., Siffert, W. (1998) Enhanced fMLP-stimulated chemotaxis in human neutrophils from individuals carrying the G protein beta3 subunit 825 T-allele. FEBS Lett. 436, 155-158.
46. Virchow, S., Ansorge, N., Rosskopf, D., Rubben, H., Siffert, W. (1999) The G protein beta3 subunit splice variant Gbeta3-s causes enhanced chemotaxis of human neutrophils in response to interleukin-8. Naunyn-Schmiedeberg's Arch. Pharmacol. 360, 27-32.
47. Luttrell, L. M., Ferguson, S. S., Daaka, Y., Miller, W. E., Maudsley, S., Della Rocca, G. J., Lin, F., Kawakatsu, H., Owada, K., Luttrell, D. K., Caron, M. G., Lefkowitz, R. J. (1999) Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes. Science 283, 655-661.
48. McDonald, P. H., Chow, C. W., Miller, W. E., Laporte, S. A., Field, M. E., Lin, F. T., Davis, R. J., Lefkowitz, R. J. (2000) Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3. Science 290, 1574-1577.
49. Neptune, E. R., Iiri, T., Bourne, H. R. (1999) Galphai is not required for chemotaxis mediated by Gi-coupled receptors. J. Biol. Chem. 274, 2824-2828.