Intramuscular fatty acid metabolism in contracting and non-contracting human skeletal muscle

Journal of Physiology

Volumn 540, Issue 1, 2002, Pages 387-395

  Sacchetti, M ^a,b   Saltin, B ^a   Osada, T ^a   Van Hall, G ^a  

^a Mental Health Services CPH   (Denmark)

^b Rigshospitalet   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON 13; FATTY ACID; PALMITIC ACID C 13; RADIOPHARMACEUTICAL AGENT; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CONTROLLED STUDY; EXTENSOR MUSCLE; FATTY ACID METABOLISM; FATTY ACID OXIDATION; FATTY ACID SYNTHESIS; FATTY ACID TRANSPORT; FOREARM; HUMAN; HUMAN EXPERIMENT; KINETICS; KNEE; LIPID STORAGE; MALE; MUSCLE CONTRACTION; MUSCLE EXERCISE; MUSCLE METABOLISM; NORMAL HUMAN; PRIORITY JOURNAL; SKELETAL MUSCLE; VEIN; WORK CAPACITY; BLOOD SAMPLING; FATTY ACID ANALYSIS; HUMAN TISSUE; KNEE EXTENSOR MUSCLE; LIPID TRANSPORT; MOLECULAR DYNAMICS;

ADULT; CARBON ISOTOPES; ENERGY METABOLISM; EXERTION; FATTY ACIDS, NONESTERIFIED; HUMANS; MALE; MUSCLE CONTRACTION; MUSCLE, SKELETAL; OXIDATION-REDUCTION; PALMITATES; TRIGLYCERIDES;

EID: 0036554698     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.2001.013912     Document Type: Article

References (33)

1. ANDERSSON, A., SJODIN, A., HEDMAN, A., OLSSON, R. & VESSBY, B. (2000). Fatty acid profile of skeletal muscle phospholipids in trained and untrained young men. American Journal of Physiology 279, E744-751.
2. BODEN, G., LEBED, B., SCHATZ, M., HOMKO, C. & LEMIEUX, S. (2001). Effects of acute changes of plasma free fatty acids on intramyocellular fat content and insulin resistance in healthy subjects. Diabetes 50, 1612-1617.
3. BUDOHOSKI, L., GORSKI, J., NAZAR, K., KACIUBA-USCILKO, H. & TERJUNG, R. L. (1996). Triacylglycerol synthesis in the different skeletal muscle fiber sections of the rat. American Journal of Physiology 271, E574-581.
4. CARLSON, L. A., EKELUND, L. G. & FRÖBERG, S. O. (1971). Concentration of triglycerides, phospholipids and glycogen in skeletal muscle and of free fatty acids and beta-hyroxybutyric acid in blood in man in response to exercise. Acta Physiologica Scandinavica 89, 374-383.
5. COLEMAN, R. A., LEWIN, T. M. & MUOIO, D. M. (2000). Physiological and nutritional regulation of enzymes of triacylglycerol synthesis. Annual Review of Nutition 20, 77-103.
6. COSTILL, D. L., GOLLNICK, P. D., JANSSON, E. D., SALTIN, B. & STEIN, E. M. (1973). Glycogen depletion pattern in human muscle fibres during distance running. Acta Physiologica Scandinavica 89, 374-383.
7. DYCK, D. J. & BONEN, A. (1998). Muscle contraction increases palmitate esterification and oxidation and triacylglycerol oxidation. American Journal of Physiology 275, E888-896.
8. DYCK, D. J., PETERS, S. J., GLATZ, J., GORSKI, J., KEIZER, H., KIENS, B., LIU S., RICHTER, E. A., SPRIET, L. L., VAN DER VUSSE, G. J. & BONEN, A. (1997). Functional differences in lipid metabolism in resting skeletal muscle of various fiber types. American Journal of Physiology 272, E340-351.
9. DYCK, D. J., STEINBERG, G. & BONEN, A. (2001). Insulin increases FA uptake and esterification but reduces lipid utilization in isolated contracting muscle. American Journal of Physiology 281, E600-607.
10. FOLCH, J., LEES, M. & STANLEY, G. H. (1957). A simple method for the isolation and purification of total lipids from animal tissues. Journal of Biological Chemistry 226, 497-510.
11. FROBERG, S. O. & MOSSFELDT, F. (1971). Effect of prolonged strenuous exercise on the concentration of triglycerides, phospholipids and glycogen in muscle of man. Acta Physiologica Scandinavica 82, 167-171.
12. GORSKI, J. (1992). Muscle triglyceride metabolism during exercise. Canadian Journal of Physiology and Pharmacology 70, 123-131.
13. GORSKI, J. & BONEN, A. (1997). Palmitate incorporation into lipids pools of contracting red and white muscles. Molecular and Cellular Biochemistry 166, 73-83.
14. GUO, Z., BURGUERA, B. & JENSEN, M. D. (2000). Kinetics of intramuscular triglyceride fatty acids in exercising humans. Journal of Applied Physiology 89, 2057-2064.
15. GUO, Z. & JENSEN, M. D. (1998). Intramuscular fatty acid metabolism evaluated with stable isotopic tracers. Journal of Applied Physiology 84, 1674-1679.
16. GUO, Z., MISHRA, P. & MACURA, S. (2001). Sampling the intramyocellular triglycerides from skeletal muscle. Journal of Lipid Research 42, 1041-1048.
17. HOLM, C., OSTERLUND, T., LAURELL, H. & CONTRERAS, J. A. (2000). Molecular mechanisms regulating hormone-sensitive lipase and lipolysis. Annual Review of Nutrition 20, 365-393.
18. HOPP, J. F. & PALMER, W. K. (1990). Electrical stimulation alters fatty acid metabolism in isolated skeletal muscle. Journal of Applied Physiology 68, 2473-2481.
19. HURLEY, B. F., NEMETH, P. M., MARTIN, W. H. 3RD, HAGBERG, J. M., DALSKY, G. P. & HOLLOSZY, J. O. (1986). Muscle triglyceride utilization during exercise: effect of training. Journal of Applied Physiology 60, 562-567.
20. KIENS, B., ESSEN-GUSTAVSSON, B., CHRISTENSEN, N. J. & SALTIN, B. (1993).Skeletal muscle substrate utilization during submaximal exercise in man: effect of endurance training. Journal of Physiology 469, 459-478.
21. KIENS, B. & RICHTER, E. A. (1998).Utilization of skeletal muscle triacylglycerol during postexercise recovery in humans. American Journal of Physiology 275, E332-337.
22. KIENS, B., ROEMEN, T. H. & VAN DER VUSSE, G. J. (1999). Muscular long-chain fatty acid content during graded exercise in humans. American Journal of Physiology 276, E352-357.
23. KJAER, M., HOWLETT, K., LANGFORT, J., ZIMMERMAN-BELSING, T., LORENTSEN, J., BULOW, J., IHLEMANN, J., FELDT-RASMUSSEN, U. & GALBO, H. (2000). Adrenaline and glycogenolysis in skeletal muscle during exercise: a study in adrenalectomised humans. Journal of Physiology 528, 371-378.
24. LANGFORT, J., PLOUG, T., IHLEMANN, J., SALDO, M., HOLM, C.& GALBO, H. (1999). Expression of hormone-sensitive lipase and its regulation by adrenaline in skeletal muscle. Biochemical Journal 340, 459-465.
25. MORGAN, T. E., SHORT, F. A. & COBB, L. A. (1969). Effect of long-term exercise on skeletal muscle lipid composition. American Journal of Physiology 216, 82-86.
26. PATTERSON, B. W., ZHAO, G., ELIAS, N., HACHEY, D. L. & KLEIN, S. (1999). Validation of a new procedure to determine plasma fatty acid concentration and isotopic enrichment. Journal of Lipid Research 40, 2118-2124.
27. RÅDEGRAN, G. (1997). Ultrasound Doppler estimates of femoral artery blood flow during dynamic knee extensor exercise in humans. Journal of Applied Physiology 83, 1383-1388.
28. RÅDEGRAN, G., BLOMSTRAND, E. & SALTIN, B. (1999). Peak muscle perfusion and oxygen uptake in humans: importance of precise estimates of muscle mass. Journal of Applied Physiology 87, 2375-2380.
29. STARLING, R. D., TRAPPE, T. A., PARCELL, A. C., KERR, C. G., FINK, W. J. & COSTILL, D. L. (1997).Effects of diet on muscle triglyceride and endurance performance. Journal of Applied Physiology 82, 1185-1189.
30. VAN DER VUSSE, G. J. & RENEMAN, R. S.(1996). Lipid metabolism in muscle. In Handbook of Physiology, section 12, Exercise: Regulation and Integration of Multiple Sytems, ed. ROWELL, L. B. & SHEPARD, J. T., pp. 952-994. Oxford Univeristy Press, New York.
31. VAN HALL, G. (1999). Correction factors for 13C-labelled substrate oxidation at whole-body and muscle level. Proceedings of the Nutrition Society 58, 979-86.
32. VAN HALL, G., GONZALEZ-ALONSO, J., SACCHETTI, M. & SALTIN, B. (1999). Skeletal muscle substrate metabolism during exercise: methodological considerations. Proceedings of the Nutrition Society 58, 899-912.
33. 2 background enrichment during exercise: diet related differenced between Europe and America. Journal of Applied Physiology 74, 2353-2357.