Correction factors for 13C-labelled substrate oxidation at whole-body and muscle level

Proceedings of the Nutrition Society

Volumn 58, Issue 4, 1999, Pages 979-986

  Van Hall, Gerrit ^a  

^a Rigshospitalet   (Denmark)

Author keywords

Acetate; Bicarbonate; Carbohydrate; Exercise; Fatty acids

Indexed keywords

CARBON 13; ACETIC ACID DERIVATIVE; BICARBONATE; CARBON; CARBON DIOXIDE;

AMINO ACID METABOLISM; CARBOHYDRATE METABOLISM; CONFERENCE PAPER; EXERCISE; FATTY ACID OXIDATION; HUMAN; ISOTOPE LABELING; MUSCLE METABOLISM; OXIDATION; METABOLISM; OXIDATION REDUCTION REACTION; REVIEW; SKELETAL MUSCLE;

ACETATES; BICARBONATES; CARBON DIOXIDE; CARBON ISOTOPES; HUMANS; ISOTOPE LABELING; MUSCLE, SKELETAL; OXIDATION-REDUCTION;

EID: 0033237419     PISSN: 00296651     EISSN: None     Source Type: Journal    
DOI: 10.1017/s0029665199001299     Document Type: Article

References (33)

1. Balasse EO (1970) Kinetics of ketone body metabolism in fasting humans. Metabolism 28, 41-50.
2. 13C]bicarbonate washout kinetics. American Journal of Physiology 259, R163-R171.
3. Bleiberg B, Beers TR, Persson M & Miles JM (1992) Systemic and regional acetate kinetics in dogs. American Journal of Physiology 262, E197-E202.
4. Bowtell JL, Leese GP, Smith K, Watt PW, Nevill A, Rooyackers O, Wagenmakers AJM & Rennie MJ (1998) Modulation of whole body protein metabolism, by variation of dietary protein. Journal of Applied Physiology 85, 1744-1752.
5. Bowtell JL, Reynolds N & Rennie MJ (1994) Differential modulation of 13C recovery during 13C bicarbonate infusion, by dietary protein and glucose supplementation, at rest and during exercise. Clinical Science 87, 57-58.
6. Coyle EF, Jeukendrup AE, Wagenmakers AJM & Saris WHM (1997) Fatty acid oxidation is directly regulated by carbohydrate metabolism during exercise. American Journal of Physiology 273, E268-E275.
7. Dagenais GR, Tancredi RG & Zierler KL (1976) Free fatty acid oxidation by forearm muscle at rest, and evidence for an intramuscular lipid pool in the human forearm. Journal of Clinical Investigation 58, 421-431.
8. Elia M, Fuller NJ & Murgatroyd PR (1993) Measurement of bicarbonate turnover in humans applicability to estimation of energy expenditure. American Journal of Physiology 263, E676-E687.
9. 3 infusion. American Journal of Physiology 269, E172-E182.
10. Hagenfeldt L & Wahren J (1968) Human forearm metabolism during exercise. Uptake, release and oxidation of individual fatty acids and glycerol. Scandinavian Journal of Clinical and Laboratory Investigation 21, 263-276.
11. Havel RJ, Pernow B & Jones NL (1967) Uptake and release of free fatty acids and other metabolites in the legs of exercising men. Journal of Applied Physiology 23, 90-99.
12. Heiling VJ, Miles JM & Jensen MD (1991) How valid are isotopic measurements of fatty acids? American Journal of Physiology 261, E572-E577.
13. Hellerstein MK, Christiansen M, Kaempfer S, Kletke C, Wu K, Reid JS, Mulligan K, Hellerstein NS & Shackleton CHL (1991a) Measurement of de novo hepatic lipogenesis in humans using stable isotopes. Journal of Clinical Investigation 87, 1841-1852.
14. Hellerstein MK, Kletke C, Kaempfer S, Wu K & Shackleton CHL (1991b) Use of mass isotopomer distributions in secreted lipids to sample lipogenic acetyl-CoA pool in vivo in humans. American Journal of Physiology 261, E479-E486.
15. 13C]bicarbonate kinetics in humans: intra- vs inter-individual variations. American Journal of Physiology 245, R190-R202.
16. Irving CS, Wong WW, Wong WM, Boutton TW, Shulman RJ, Lifschitz CL, Malphus EW, Helge H & Klein PD (1984) Rapid determination of whole-body bicarbonate kinetics by use of digital infusion. American Journal of Physiology 247, R709-R716.
17. 14C-labelled bicarbonate in the cat. Biochemical Journal 51, 351-357.
18. 13C bicarbonate: the effects of exercise and acid base balance. European Journal of Clinical Investigation 24, 818-823.
19. 2 in human bicarbonate studies: a critical review with original data. Clinical Science 91, 665-677.
20. Mittendorfer B, Sidossis LS, Walser E, Chinkes DL & Wolfe RR (1998) Regional acetate kinetics and oxidation in human volunteers. American Journal of Physiology 274, E978-E983.
21. 13C]acetate. American Journal of Physiology 271,E58-E64.
22. 13C]palmitate oxidation rates in humans. Journal of Physiology 513, 215-223.
23. 14C studies in carbohydrate metabolism. IV. Characteristics of bicarbonate pool system in the rat. American Journal of Physiology 197, 41-46.
24. Sidossis LS, Coggan AR, Gastaldelli A & Wolfe RR (1995a) A new correction factor for use in a tracer estimations of plasma fatty acid oxidation. American Journal of Physiology 269, E649-E656.
25. Sidossis LS, Coggan AR, Gastaldelli A & Wolfe RR (1995b) Pathways of free fatty acid oxidation in human subjects - Implications for tracer studies. Journal of Clinical Investigation 95, 278-284.
26. Sidossis LS, Stuart CA, Shulman GI, Lopaschuk GD & Wolfe RR (1996) Glucose plus insulin regulate fat oxidation by controlling the rate of fatty acid entry into mitochondria. Journal of Clinical Investigation 98, 2244-2250.
27. 3- kinetics. Journal of Nuclear Medicine 11, 716-718.
28. Steel R (1955) The retention of metabolic radioactive carbonate. Biochemical Journal 60, 447-552.
29. Tamopolsky MA, Atkinson SA, MacDougall JD, Senor BB, Lemon PWR & Schwarcz H (1991) Whole body leucine metabolism during and after resistance exercise in fed humans. Medicine and Science in Sports and Exercise 23, 326-333.
30. Tounian P, Schneiter P, Henry S & Tappy L (1996) Effect of infused glucose on glycogen metabolism. Clinical Physiology 16, 403-416.
31. 13C]acetate infusion. Proceedings of the Nutrition Society 58, 166A.
32. 2 during the infusion of C-1 vs C-2-labeled acetate: implication for tracer studies of substrate oxidation. American Journal of Clinical Nutrition 51, 248-252.
33. Wolfe RR, Wolfe MH, Nadel ER & Shaw JHF (1984) Isotopic determination of amino acid-urea interaction in exercise in humans. Journal of Applied Physiology 52, 221-224.