Novel strategy for the selection of human recombinant Fab fragments to membrane proteins from a phage-display library

Journal of Immunological Methods

Volumn 261, Issue 1-2, 2002, Pages 37-48

  Labrijn, Aran F ^a,b   Koppelman, Marco H G M ^a   Verhagen, Janneke ^a   Brouwer, Mieke C ^a   Schuitemaker, Hanneke ^a   Hack, C Erik ^a   Huisman, Han G ^a,b  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b CENTRAL LABORATORY   (Netherlands)

Author keywords

HIV 1; Membrane proteins; n Octyl D glucopyranoside; Phage display libraries; Recombinant Fab; Selection

Indexed keywords

AGGLUTININ; ANTIGEN; ENVELOPE PROTEIN; IMMUNOGLOBULIN F(AB) FRAGMENT; MEMBRANE PROTEIN; OCTYL GLUCOSIDE; TRITON X 114;

ANIMAL CELL; ARTICLE; CELL STRAIN; CONTROLLED STUDY; GEL FILTRATION; GENE EXPRESSION; GENE LIBRARY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; KIDNEY CELL; MEMBRANE VESICLE; MICROTITER PLATE ASSAY; MOLECULAR CLONING; MOUSE; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL; RABBIT; SOLUBILIZATION; SURFACE PROPERTY; VACCINIA VIRUS;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS; BASE SEQUENCE; CELL LINE; DETERGENTS; DNA; DNA FINGERPRINTING; GENE PRODUCTS, ENV; HIV ANTIBODIES; HIV ANTIGENS; HIV SEROPOSITIVITY; HIV-1; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; RABBITS; RECOMBINANT PROTEINS; SOLUBILITY;

GALANTHUS; GALANTHUS NIVALIS; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; ORYCTOLAGUS CUNICULUS; VACCINIA VIRUS;

EID: 0036499304     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-1759(01)00542-7     Document Type: Article

References (52)

1. The interaction of Sendai virus glycoprotein-bearing recombinant vesicles with cell surfaces
2. Major glycoprotein antigens that induce antibodies in AIDS patients are encoded by HTLV-III
3. Molecular profile of an antibody response to HIV-1 as probed by combinatorial libraries
4. Human antibody responses to HIV type 1 glycoprotein 41 cloned in phage display libraries suggest three major epitopes are recognized and give evidence for conserved antibody motifs in antigen binding
5. A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits is an antigenic mimic of the trimeric virion-associated structure
6. Ubiquitination of the human immunodeficiency virus type 1 env glycoprotein
7. Human antibodies from combinatorial libraries
8. A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic seropositive individuals
9. Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody
10. Anti-melanoma antibodies from melanoma patients immunized with genetically modified autologous tumor cells: Selection of specific antibodies from single-chain Fv fusion phage libraries
11. CD4 is retained in the endoplasmic reticulum by the human immunodeficiency virus type 1 glycoprotein precursor
12. Rapid selection of cell subpopulation-specific human monoclonal antibodies from a synthetic phage antibody library
13. Mapping the protein surface of human immunodeficiency virus type 1 gp120 using human monoclonal antibodies from phage display libraries
14. Folding, interaction with GRP78-BiP, assembly, and transport of the human immunodeficiency virus type 1 envelope protein
15. pH-dependent fusion induced by vesicular stomatitis virus glycoprotein reconstituted into phospholipid vesicles
16. Phenotype-associated sequence variation in the third variable domain of the human immunodeficiency virus type 1 gp120 molecule
17. Neutralization of the human immunodeficiency virus type 1 primary isolate JR-FL by human monoclonal antibodies correlates with antibody binding to the oligomeric form of the envelope glycoprotein complex
18. Envelope glycoproteins of HIV-1, HIV-2, and SIV purified with Galanthus nivalis agglutinin induce strong immune responses
19. Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gp160
20. Reconstitution and fusogenic properties of Sendai virus envelopes
21. Formation of polymeric glycoprotein complexes from a flavivirus: Tick-borne encephalitis virus
22. Selection of cell binding and internalizing epidermal growth factor receptor antibodies from a phage display library
23. The effects of octylglucoside on the Semliki forest virus membrane. Evidence for a spike-protein-nucleocapsid interaction
24. Enzyme immunoassay (ELISA) for the evaluation of antibodies directed to the CD4 receptor-binding site of the HIV gp120 molecule
25. Natural and designer binding sites made by phage display technology
26. Fusion between cell membrane and liposomes containing the glycoproteins of influenza virus
27. In vivo selection of sFv from phage display libraries
28. Selection procedures for nonmatured phage antibodies: A quantitative comparison and optimization strategies
29. A trimeric structural domain of the HIV-1 transmembrane glycoprotein
30. An ELISA utilizing immobilised snowdrop lectin GNA for the detection of envelope glycoproteins of HIV and SIV
31. By-passing immunization. Human antibodies from V-gene libraries displayed on phage
32. Human antibody fragments specific for human blood group antigens from a phage display library
33. Model systems to study the parameters determining the success of phage antibody selections on complex antigens
34. Pathfinder selection: In situ isolation of novel antibodies
35. In vitro antigen challenge of human antibody libraries for vaccine evaluation: The human immunodeficiency virus type 1 envelope
36. HIV-1 antibody-debris or virion?
37. Neutralization of human immunodeficiency virus type 1 by antibody to gp120 is determined primarily by occupancy of sites on the virion irrespective of epitope specificity
38. Solubilization and reconstitution of vesicular stomatitis virus envelope using octylglucoside
39. Generation of diverse high-affinity human monoclonal antibodies by repertoire cloning
40. Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human immunodeficiency virus type 1
41. Characterization of envelope and core structural gene products of HTLV-III with sera from AIDS patients
42. Directed selection of recombinant human monoclonal antibodies to herpes simplex virus glycoproteins from phage display libraries
43. Human immunodeficiency virus type 1 neutralization is determined by epitope exposure on the gp120 oligomer
44. Methodology for selection of human antibodies to membrane proteins from a phage-display library
45. Preparation and characterization of F-protein vesicles isolated from Sendai virus by means of octyl glucoside
46. Isolation of cell surface-specific human monoclonal antibodies using phage display and magnetically-activated cell sorting: Applications in immunohematology
47. Generation and structural analysis of soluble oligomeric gp140 envelope proteins derived from neutralization-resistant and neutralization-susceptible primary HIV type 1 isolates
48. Functional reconstitution of influenza virus envelopes
49. Efficient selection of scFv antibody phage by adsorption to in situ expressed antigens in tissue sections
50. Biosynthesis, cleavage, and degradation of the human immunodeficiency virus 1 envelope glycoprotein gp160
51. Making antibodies by phage display technology
52. The HIV-1 envelope glycoproteins: Fusogens, antigens, and immunogens